标题
Strong Purifying Selection at Synonymous Sites in D. melanogaster
作者
关键词
-
出版物
PLoS Genetics
Volume 9, Issue 5, Pages e1003527
出版商
Public Library of Science (PLoS)
发表日期
2013-05-31
DOI
10.1371/journal.pgen.1003527
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Differential requirements for mRNA folding partially explain why highly expressed proteins evolve slowly
- (2013) C. Park et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Strong association between mRNA folding strength and protein abundance in S. cerevisiae
- (2012) Hadas Zur et al. EMBO REPORTS
- Unconstrained evolution in short introns? - An analysis of genome-wide polymorphism and divergence data from Drosophila
- (2012) F. Clemente et al. JOURNAL OF EVOLUTIONARY BIOLOGY
- Evidence for complex selection on four-fold degenerate sites inDrosophila melanogaster
- (2012) F. Clemente et al. JOURNAL OF EVOLUTIONARY BIOLOGY
- Selection on Synonymous Sites for Increased Accessibility around miRNA Binding Sites in Plants
- (2012) Wanjun Gu et al. MOLECULAR BIOLOGY AND EVOLUTION
- Good Codons, Bad Transcript: Large Reductions in Gene Expression and Fitness Arising from Synonymous Mutations in a Key Enzyme
- (2012) Deepa Agashe et al. MOLECULAR BIOLOGY AND EVOLUTION
- The Drosophila melanogaster Genetic Reference Panel
- (2012) Trudy F. C. Mackay et al. NATURE
- Evolutionary conservation of codon optimality reveals hidden signatures of cotranslational folding
- (2012) Sebastian Pechmann et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The UCSC Genome Browser database: extensions and updates 2013
- (2012) Laurence R. Meyer et al. NUCLEIC ACIDS RESEARCH
- Nucleosomes Suppress Spontaneous Mutations Base-Specifically in Eukaryotes
- (2012) Xiaoshu Chen et al. SCIENCE
- The allele-frequency spectrum in a decoupled Moran model with mutation, drift, and directional selection, assuming small mutation rates
- (2012) Claus Vogl et al. THEORETICAL POPULATION BIOLOGY
- Speeding with control: codon usage, tRNAs, and ribosomes
- (2012) Eva Maria Novoa et al. TRENDS IN GENETICS
- Global Analysis of RNA Secondary Structure in Two Metazoans
- (2012) Fan Li et al. Cell Reports
- Nucleoid-Associated Proteins Affect Mutation Dynamics in E. coli in a Growth Phase-Specific Manner
- (2012) Tobias Warnecke et al. PLoS Computational Biology
- Balanced Codon Usage Optimizes Eukaryotic Translational Efficiency
- (2012) Wenfeng Qian et al. PLoS Genetics
- Genome-wide DNA sequence polymorphisms facilitate nucleosome positioning in yeast
- (2011) Zhiming Dai et al. BIOINFORMATICS
- Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes
- (2011) Nicholas T. Ingolia et al. CELL
- Inference of Site Frequency Spectra From High-Throughput Sequence Data: Quantification of Selection on Nonsynonymous and Synonymous Sites in Humans
- (2011) Peter D. Keightley et al. GENETICS
- Significant Selective Constraint at 4-Fold Degenerate Sites in the Avian Genome and Its Consequence for Detection of Positive Selection
- (2011) Axel Künstner et al. Genome Biology and Evolution
- Faster than Neutral Evolution of Constrained Sequences: The Complex Interplay of Mutational Biases and Weak Selection
- (2011) David S. Lawrie et al. Genome Biology and Evolution
- Selection for Translation Efficiency on Synonymous Polymorphisms in Recent Human Evolution
- (2011) Yedael Y. Waldman et al. Genome Biology and Evolution
- Widespread signatures of recent selection linked to nucleosome positioning in the human lineage
- (2011) J. G. D. Prendergast et al. GENOME RESEARCH
- High sensitivity to aligner and high rate of false positives in the estimates of positive selection in the 12 Drosophila genomes
- (2011) P. Markova-Raina et al. GENOME RESEARCH
- A synonymous polymorphism of the Tristetraprolin (TTP) gene, an AU-rich mRNA-binding protein, affects translation efficiency and response to Herceptin treatment in breast cancer patients
- (2011) Paola Griseri et al. HUMAN MOLECULAR GENETICS
- Genome-Wide Survey of Natural Selection on Functional, Structural, and Network Properties of Polymorphic Sites in Saccharomyces paradoxus
- (2011) A. Vishnoi et al. MOLECULAR BIOLOGY AND EVOLUTION
- Understanding the contribution of synonymous mutations to human disease
- (2011) Zuben E. Sauna et al. NATURE REVIEWS GENETICS
- FlyBase 101 - the basics of navigating FlyBase
- (2011) P. McQuilton et al. NUCLEIC ACIDS RESEARCH
- Wobble base-pairing slows in vivo translation elongation in metazoans
- (2011) M. Stadler et al. RNA
- Composite effects of gene determinants on the translation speed and density of ribosomes
- (2011) Tamir Tuller et al. GENOME BIOLOGY
- An Evolutionarily Conserved Mechanism for Controlling the Efficiency of Protein Translation
- (2010) Tamir Tuller et al. CELL
- Folding at the birth of the nascent chain: coordinating translation with co-translational folding
- (2010) Gong Zhang et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Effective Population Size and the Efficacy of Selection on the X Chromosomes of Two Closely Related Drosophila Species
- (2010) Peter Andolfatto et al. Genome Biology and Evolution
- On the Utility of Short Intron Sequences as a Reference for the Detection of Positive and Negative Selection in Drosophila
- (2010) J. Parsch et al. MOLECULAR BIOLOGY AND EVOLUTION
- Determinants of Synonymous and Nonsynonymous Variability in Three Species of Drosophila
- (2010) Penelope R. Haddrill et al. MOLECULAR BIOLOGY AND EVOLUTION
- Detecting Positive and Purifying Selection at Synonymous Sites in Yeast and Worm
- (2010) T. Zhou et al. MOLECULAR BIOLOGY AND EVOLUTION
- The developmental transcriptome of Drosophila melanogaster
- (2010) Brenton R. Graveley et al. NATURE
- Synonymous but not the same: the causes and consequences of codon bias
- (2010) Joshua B. Plotkin et al. NATURE REVIEWS GENETICS
- Translation efficiency is determined by both codon bias and folding energy
- (2010) Tamir Tuller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Control of translation efficiency in yeast by codon-anticodon interactions
- (2010) D. P. Letzring et al. RNA
- New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0
- (2010) Stéphane Guindon et al. SYSTEMATIC BIOLOGY
- A Universal Trend of Reduced mRNA Stability near the Translation-Initiation Site in Prokaryotes and Eukaryotes
- (2010) Wanjun Gu et al. PLoS Computational Biology
- Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP++
- (2010) Eugene V. Davydov et al. PLoS Computational Biology
- Evidence of Selection upon Genomic GC-Content in Bacteria
- (2010) Falk Hildebrand et al. PLoS Genetics
- Evidence That Mutation Is Universally Biased towards AT in Bacteria
- (2010) Ruth Hershberg et al. PLoS Genetics
- MicroRNAs: Target Recognition and Regulatory Functions
- (2009) David P. Bartel CELL
- Estimating Selection Intensity on Synonymous Codon Usage in a Nonequilibrium Population
- (2009) K. Zeng et al. GENETICS
- Locus-Specific Decoupling of Base Composition Evolution at Synonymous Sites and Introns along the Drosophila melanogaster and Drosophila sechellia Lineages
- (2009) Vanessa L. Bauer DuMont et al. Genome Biology and Evolution
- Detection of nonneutral substitution rates on mammalian phylogenies
- (2009) K. S. Pollard et al. GENOME RESEARCH
- Studying Patterns of Recent Evolution at Synonymous Sites and Intronic Sites in Drosophila melanogaster
- (2009) Kai Zeng et al. JOURNAL OF MOLECULAR EVOLUTION
- Natural Selection on Synonymous and Nonsynonymous Mutations Shapes Patterns of Polymorphism in Populus tremula
- (2009) P. K. Ingvarsson MOLECULAR BIOLOGY AND EVOLUTION
- Distributions of Selectively Constrained Sites and Deleterious Mutation Rates in the Hominid and Murid Genomes
- (2009) L. Eory et al. MOLECULAR BIOLOGY AND EVOLUTION
- Strong Evidence for Lineage and Sequence Specificity of Substitution Rates and Patterns in Drosophila
- (2009) N. D. Singh et al. MOLECULAR BIOLOGY AND EVOLUTION
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- Transient ribosomal attenuation coordinates protein synthesis and co-translational folding
- (2009) Gong Zhang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Coding-Sequence Determinants of Gene Expression in Escherichia coli
- (2009) G. Kudla et al. SCIENCE
- Pervasive Natural Selection in the Drosophila Genome?
- (2009) Guy Sella et al. PLoS Genetics
- General Rules for Optimal Codon Choice
- (2009) Ruth Hershberg et al. PLoS Genetics
- Selection on Codon Bias
- (2008) Ruth Hershberg et al. Annual Review of Genetics
- Conflicting selection pressures on synonymous codon use in yeast suggest selection on mRNA secondary structures
- (2008) Nina Stoletzki BMC EVOLUTIONARY BIOLOGY
- Mistranslation-Induced Protein Misfolding as a Dominant Constraint on Coding-Sequence Evolution
- (2008) D. Allan Drummond et al. CELL
- Developmental Stage and Level of Codon Usage Bias in Drosophila
- (2008) Saverio Vicario et al. MOLECULAR BIOLOGY AND EVOLUTION
- Mutation-Selection Models of Codon Substitution and Their Use to Estimate Selective Strengths on Codon Usage
- (2008) Z. Yang et al. MOLECULAR BIOLOGY AND EVOLUTION
- Nucleosome organization in the Drosophila genome
- (2008) Travis N. Mavrich et al. NATURE
- Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists
- (2008) Da Wei Huang et al. NUCLEIC ACIDS RESEARCH
- A genome-wide view of the spectrum of spontaneous mutations in yeast
- (2008) M. Lynch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phylogeny-Aware Gap Placement Prevents Errors in Sequence Alignment and Evolutionary Analysis
- (2008) A. Loytynoja et al. SCIENCE
- The Impact of the Nucleosome Code on Protein-Coding Sequence Evolution in Yeast
- (2008) Tobias Warnecke et al. PLoS Genetics
- Assessing the Evolutionary Impact of Amino Acid Mutations in the Human Genome
- (2008) Adam R. Boyko et al. PLoS Genetics
- Contrasting the Efficacy of Selection on the X and Autosomes in Drosophila
- (2007) N. D. Singh et al. MOLECULAR BIOLOGY AND EVOLUTION
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started