Epidemic Spreading Model to Characterize Misfolded Proteins Propagation in Aging and Associated Neurodegenerative Disorders

Immunotherapy for Alzheimer's disease

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The hubs of the human connectome are generally implicated in the anatomy of brain disorders

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Spreading of amyloid-β peptides via neuritic cell-to-cell transfer is dependent on insufficient cellular clearance

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Aβ and tau toxicities in Alzheimer’s are linked via oxidative stress-induced p38 activation: Protective role of vitamin E

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β-Amyloid is transmitted via neuronal connections along axonal membranes

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Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

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APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study

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Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

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Microstructural grey matter parcellation and its relevance for connectome analyses

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Networks of anatomical covariance

(2013) Alan C. Evans   NEUROIMAGE

Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta

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Increased Amyloid-β Peptide-Induced Memory Deficits in Phospholipid Transfer Protein (PLTP) Gene Knockout Mice

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Neuron-to-Neuron Transmission of Neurodegenerative Pathology

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The Hidden Geometry of Complex, Network-Driven Contagion Phenomena

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Increased in Vivo Amyloid- 42 Production, Exchange, and Loss in Presenilin Mutation Carriers

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Network hubs in the human brain

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Evidence for impaired amyloid β clearance in Alzheimer's disease

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Apolipoprotein E4 effects in Alzheimer’s disease are mediated by synaptotoxic oligomeric amyloid-β

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Corruption and Spread of Pathogenic Proteins in Neurodegenerative Diseases

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Spreading of Neurodegenerative Pathology via Neuron-to-Neuron Transmission of  -Amyloid

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Gender Modulates the APOE  4 Effect in Healthy Older Adults: Convergent Evidence from Functional Brain Connectivity and Spinal Fluid Tau Levels

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A Network Diffusion Model of Disease Progression in Dementia

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Predicting Regional Neurodegeneration from the Healthy Brain Functional Connectome

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ApoE-Directed Therapeutics Rapidly Clear  -Amyloid and Reverse Deficits in AD Mouse Models

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Activity Dependent Degeneration Explains Hub Vulnerability in Alzheimer's Disease

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Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI

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APOE and Alzheimer disease: a major gene with semi-dominant inheritance

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The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

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NTU-90: A high angular resolution brain atlas constructed by q-space diffeomorphic reconstruction

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Weight-conserving characterization of complex functional brain networks

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Alzheimer's Disease: The Challenge of the Second Century

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Human apoE Isoforms Differentially Regulate Brain Amyloid-  Peptide Clearance

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Misfolded protein aggregates: Mechanisms, structures and potential for disease transmission

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The Alzheimer's Disease Neuroimaging Initiative positron emission tomography core

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Autophagy and misfolded proteins in neurodegeneration

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Evidence for the Default Network's Role in Spontaneous Cognition

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11C-PiB PET assessment of change in fibrillar amyloid-β load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study

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Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

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Prion-like transmission of protein aggregates in neurodegenerative diseases

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Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

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Twenty-five pitfalls in the analysis of diffusion MRI data

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The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide

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The Concentration of Soluble Extracellular Amyloid-β Protein in Acute Brain Slices from CRND8 Mice

(2010) Jack Waters   PLoS One

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

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Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

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Immune defects in Alzheimer's disease: new medications development

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Biomarkers in Relation to Cognitive Reserve in Patients with Mild Cognitive Impairment – Proof of Concept

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Propagation of Tau Misfolding from the Outside to the Inside of a Cell

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Cortical Hubs Revealed by Intrinsic Functional Connectivity: Mapping, Assessment of Stability, and Relation to Alzheimer's Disease

(2009) R. L. Buckner et al.   JOURNAL OF NEUROSCIENCE

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

(2009) Clifford R Jack et al.   LANCET NEUROLOGY

Whole-brain anatomical networks: Does the choice of nodes matter?

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Neurodegenerative Diseases Target Large-Scale Human Brain Networks

(2009) William W. Seeley et al.   NEURON

Beta-Amyloid Deposition and the Aging Brain

(2009) Karen M. Rodrigue et al.   NEUROPSYCHOLOGY REVIEW

The Brain's Default Network

(2008) Randy L. Buckner et al.   Annals of the New York Academy of Sciences

Frequent Amyloid Deposition Without Significant Cognitive Impairment Among the Elderly

(2008) Howard Jay Aizenstein et al.   ARCHIVES OF NEUROLOGY

Graph theoretical analysis of magnetoencephalographic functional connectivity in Alzheimer's disease

(2008) C. J. Stam et al.   BRAIN

Gender and age-dependent differences in the mitochondrial apoptogenic pathway in Alzheimer's disease

(2008) Ana Lloret et al.   FREE RADICAL BIOLOGY AND MEDICINE

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

Linking Aβ and Tau in Late-Onset Alzheimer's Disease: A Dual Pathway Hypothesis

(2008) Scott A. Small et al.   NEURON

Cognitive reserve hypothesis: Pittsburgh Compound B and fluorodeoxyglucose positron emission tomography in relation to education in mild Alzheimer's disease

(2007) Nina M. Kemppainen et al.   ANNALS OF NEUROLOGY