Drug enrichment and discovery from schizophrenia genome-wide association results: an analysis and visualisation approach

The druggable genome and support for target identification and validation in drug development

(2017) Chris Finan et al.   Science Translational Medicine

Gene-set analysis based on the pharmacological profiles of drugs to identify repurposing opportunities in schizophrenia

(2016) Simone de Jong et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Chromosome conformation elucidates regulatory relationships in developing human brain

(2016) Hyejung Won et al.   NATURE

Translating genome-wide association findings into new therapeutics for psychiatry

(2016) Gerome Breen et al.   NATURE NEUROSCIENCE

Open Targets: a platform for therapeutic target identification and validation

(2016) Gautier Koscielny et al.   NUCLEIC ACIDS RESEARCH

GTM-Based QSAR Models and Their Applicability Domains

(2015) H. A. Gaspar et al.   Molecular Informatics

Targeting the schizophrenia genome: a fast track strategy from GWAS to clinic

(2015) T Lencz et al.   MOLECULAR PSYCHIATRY

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

The support of human genetic evidence for approved drug indications

(2015) Matthew R Nelson et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

DGIdb 2.0: mining clinically relevant drug–gene interactions

(2015) Alex H. Wagner et al.   NUCLEIC ACIDS RESEARCH

Ensembl 2016

(2015) Andrew Yates et al.   NUCLEIC ACIDS RESEARCH

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

The role of L-type voltage-gated calcium channels Cav1.2 and Cav1.3 in normal and pathological brain function

(2014) Stefan M. Berger et al.   CELL AND TISSUE RESEARCH

Maintenance Treatment With Varenicline for Smoking Cessation in Patients With Schizophrenia and Bipolar Disorder

(2014) A. Eden Evins et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Genenames.org: the HGNC resources in 2015

(2014) Kristian A. Gray et al.   NUCLEIC ACIDS RESEARCH

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Antipsychotic-Induced Insulin Resistance and Postprandial Hormonal Dysregulation Independent of Weight Gain or Psychiatric Disease

(2013) Karen L. Teff et al.   DIABETES

Rational drug repositioning by medical genetics

(2013) Zhong-Yi Wang et al.   NATURE BIOTECHNOLOGY

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

(2013) Stephan Ripke et al.   NATURE GENETICS

Major channels involved in neuropsychiatric disorders and therapeutic perspectives

(2013) Paola Imbrici et al.   Frontiers in Genetics

Five Years of GWAS Discovery

(2012) Peter M. Visscher et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Use of genome-wide association studies for drug repositioning

(2012) Philippe Sanseau et al.   NATURE BIOTECHNOLOGY

Mining for Bioactive Scaffolds with Scaffold Networks: Improved Compound Set Enrichment from Primary Screening Data

(2011) Thibault Varin et al.   Journal of Chemical Information and Modeling

Genome-wide association study identifies five new schizophrenia loci

(2011)   NATURE GENETICS

Deficits in GABAB receptor system in schizophrenia and mood disorders: A postmortem study

(2011) S. Hossein Fatemi et al.   SCHIZOPHRENIA RESEARCH

Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study

(2009) Paul Lichtenstein et al.   LANCET

Role of genetic variants in the CHRNA5–CHRNA3–CHRNB4 cluster in nicotine dependence risk: importance of gene–environment interplay

(2009) L Greenbaum et al.   MOLECULAR PSYCHIATRY

Galantamine for the Treatment of Cognitive Impairments in People With Schizophrenia

(2007) Robert W. Buchanan et al.   AMERICAN JOURNAL OF PSYCHIATRY

Inhibition of dipeptidyl peptidase-IV (DPP-IV) by atorvastatin

(2007) Tony Taldone et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS