Use of genome-wide association studies for drug repositioning

Database identifies FDA-approved drugs with potential to be repurposed for treatment of orphan diseases

(2011) K. Xu et al.   BRIEFINGS IN BIOINFORMATICS

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

Replication of the LINGO1 gene association with essential tremor in a North American population

(2010) Lorraine N Clark et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Multiple common variants for celiac disease influencing immune gene expression

(2010) Patrick C A Dubois et al.   NATURE GENETICS

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

(2010)   NATURE GENETICS

Genome-wide association analysis identifies three psoriasis susceptibility loci

(2010) Philip E Stuart et al.   NATURE GENETICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

E2-2 Protein and Fuchs's Corneal Dystrophy

(2010) Keith H. Baratz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Unraveling the Directional Link between Adiposity and Inflammation: A Bidirectional Mendelian Randomization Approach

(2009) Paul Welsh et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Variant in the sequence of the LINGO1 gene confers risk of essential tremor

(2009) Hreinn Stefansson et al.   NATURE GENETICS

Common variants at five new loci associated with early-onset inflammatory bowel disease

(2009) Marcin Imielinski et al.   NATURE GENETICS

Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways

(2009) Rajan P Nair et al.   NATURE GENETICS

New sequence variants associated with bone mineral density

(2008) Unnur Styrkarsdottir et al.   NATURE GENETICS

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

(2008) Sekar Kathiresan et al.   NATURE GENETICS

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS