CCN2 Is Required for the TGF-β Induced Activation of Smad1 - Erk1/2 Signaling Network

CCN2 is required for bleomycin-induced skin fibrosis in mice

(2010) Shangxi Liu et al.   ARTHRITIS AND RHEUMATISM

Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis

(2010) Sonali Sonnylal et al.   ARTHRITIS AND RHEUMATISM

Akt inhibition up-regulates MMP1 through a CCN2-dependent pathway in human dermal fibroblasts

(2010) Andreea M. Bujor et al.   EXPERIMENTAL DERMATOLOGY

Genetic variant in the promoter of connective tissue growth factor gene confers susceptibility to nephropathy in type 1 diabetes

(2010) B. Wang et al.   JOURNAL OF MEDICAL GENETICS

Transforming Growth Factor β Can Stimulate Smad1 Phosphorylation Independently of Bone Morphogenic Protein Receptors

(2009) Katharine H. Wrighton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduced Expression of Connective Tissue Growth Factor (CTGF/CCN2) Mediates Collagen Loss in Chronologically Aged Human Skin

(2009) TaiHao Quan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Sp1 Phosphorylation and Its Regulation of Gene Transcription

(2009) N. Y. Tan et al.   MOLECULAR AND CELLULAR BIOLOGY

Phosphorylation of Fli1 at Threonine 312 by Protein Kinase C   Promotes Its Interaction with p300/CREB-Binding Protein-Associated Factor and Subsequent Acetylation in Response to Transforming Growth Factor  

(2009) Y. Asano et al.   MOLECULAR AND CELLULAR BIOLOGY

Smad-Independent Transforming Growth Factor-β Regulation of Early Growth Response-1 and Sustained Expression in Fibrosis

(2008) Swati Bhattacharyya et al.   AMERICAN JOURNAL OF PATHOLOGY

Endoglin in angiogenesis and vascular diseases

(2008) Peter ten Dijke et al.   ANGIOGENESIS

Smad1 pathway is activated in systemic sclerosis fibroblasts and is targeted by imatinib mesylate

(2008) Jaspreet Pannu et al.   ARTHRITIS AND RHEUMATISM

Src kinases in systemic sclerosis: Central roles in fibroblast activation and in skin fibrosis

(2008) Catherine Skhirtladze et al.   ARTHRITIS AND RHEUMATISM

Regulation of Id1 Expression by Src: Implications for Targeting of the Bone Morphogenetic Protein Pathway in Cancer

(2008) O. Gautschi et al.   CANCER RESEARCH

Non-Smad pathways in TGF-β signaling

(2008) Ying E Zhang   CELL RESEARCH

Regulation and function of connective tissue growth factor/CCN2 in tissue repair, scarring and fibrosis

(2008) Xu Shi-Wen et al.   CYTOKINE & GROWTH FACTOR REVIEWS

TGFβ-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFβ switch

(2008) Irwin M Liu et al.   EMBO JOURNAL

Dynamic control of TGF-β signaling and its links to the cytoskeleton

(2008) Aristidis Moustakas et al.   FEBS LETTERS

uPAR promotes formation of the p130Cas–Crk complex to activate Rac through DOCK180

(2008) Harvey W. Smith et al.   JOURNAL OF CELL BIOLOGY

Connective tissue growth factor: growth factor, matricellular organizer, fibrotic biomarker or molecular target for anti-fibrotic therapy in SSc?

(2008) D. Abraham   RHEUMATOLOGY