Transcriptional Associations of Osteoarthritis-Mediated Loss of Epigenetic Control in Articular Cartilage

Knee and hip articular cartilage have distinct epigenomic landscapes: implications for future cartilage regeneration approaches

(2014) W den Hollander et al.   ANNALS OF THE RHEUMATIC DISEASES

Chopping off the chondrocyte proteome

(2014) Mona Dvir-Ginzberg et al.   BIOMARKERS

Chondrocyte hypertrophy in skeletal development, growth, and disease

(2014) Margaret Man-Ger Sun et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

CpG methylation regulates allelic expression of GDF5 by modulating binding of SP1 and SP3 repressor proteins to the osteoarthritis susceptibility SNP rs143383

(2014) Louise N. Reynard et al.   HUMAN GENETICS

Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance

(2014) Yolande F M Ramos et al.   JOURNAL OF MEDICAL GENETICS

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

Genes Involved in the Osteoarthritis Process Identified through Genome Wide Expression Analysis in Articular Cartilage; the RAAK Study

(2014) Yolande F. M. Ramos et al.   PLoS One

IL-6-accelerated calcification by induction of ROR2 in human adipose tissue-derived mesenchymal stem cells is STAT3 dependent

(2014) Shunsuke Fukuyo et al.   RHEUMATOLOGY

Genome-Wide DNA Methylation Study Identifies Significant Epigenomic Changes in Osteoarthritic Cartilage

(2014) Matlock A. Jeffries et al.   Arthritis & Rheumatology

Characterization of the Cartilage DNA Methylome in Knee and Hip Osteoarthritis

(2014) Michael D. Rushton et al.   Arthritis & Rheumatology

Genome-wide DNA methylation analysis of articular chondrocytes reveals a cluster of osteoarthritic patients

(2013) Juan Fernández-Tajes et al.   ANNALS OF THE RHEUMATIC DISEASES

Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray

(2013) Yi-an Chen et al.   Epigenetics

Regulated Transcription of Human Matrix Metalloproteinase 13 (MMP13) and Interleukin-1β (IL1B) Genes in Chondrocytes Depends on Methylation of Specific Proximal Promoter CpG Sites

(2013) Ko Hashimoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

To Wnt or not to Wnt: the bone and joint health dilemma

(2013) Rik J. Lories et al.   Nature Reviews Rheumatology

Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development

(2013) Y. Hosaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array

(2013) Roderick C Slieker et al.   Epigenetics & Chromatin

Osteoarthritis: A disease of the joint as an organ

(2012) Richard F. Loeser et al.   ARTHRITIS AND RHEUMATISM

Gremlin 1, Frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis

(2012) J. C. H. Leijten et al.   ARTHRITIS AND RHEUMATISM

Wnt-mediated reciprocal regulation between cartilage and bone development during endochondral ossification

(2012) Cheng Lu et al.   BONE

The dual role of the novel Wnt receptor tyrosine kinase, ROR2, in human carcinogenesis

(2012) Caroline E. Ford et al.   INTERNATIONAL JOURNAL OF CANCER

Functional characterization of mammalian Wntless homolog in mammalian system

(2012) Li-Ting Wang et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

(2012)   LANCET

Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis

(2012) M. C. Castano Betancourt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osteoarthritis: an update with relevance for clinical practice

(2011) Johannes WJ Bijlsma et al.   LANCET

Changes in the Chondrocyte and Extracellular Matrix Proteome during Post-natal Mouse Cartilage Development

(2011) Richard Wilson et al.   MOLECULAR & CELLULAR PROTEOMICS

A significant association exists between receptor tyrosine kinase-like orphan receptor 2 gene variants and the OPG/RANKL ratio in human plasma

(2011) S. Ermakov et al.   OSTEOPOROSIS INTERNATIONAL

Correction: DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines

(2011) Jordana T Bell et al.   GENOME BIOLOGY

Dynamic changes in the human methylome during differentiation

(2010) L. Laurent et al.   GENOME RESEARCH

Expression of Cartilage Developmental Genes in Hoxc8- and Hoxd4-Transgenic Mice

(2010) Claudia Kruger et al.   PLoS One

Large-scale analysis of association betweenGDF5andFRZBvariants and osteoarthritis of the hip, knee, and hand

(2009) Evangelos Evangelou et al.   ARTHRITIS AND RHEUMATISM

DNA demethylation at specific CpG sites in theIL1Bpromoter in response to inflammatory cytokines in human articular chondrocytes

(2009) Ko Hashimoto et al.   ARTHRITIS AND RHEUMATISM

New insights into osteoarthritis: early developmental features of an ageing-related disease

(2008) Steffan Daniël Bos et al.   CURRENT OPINION IN RHEUMATOLOGY

Transcriptome-based systematic identification of extracellular matrix proteins

(2008) R.-i. Manabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA