Parkinson Disease: A Role for Autophagy?

Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress

(2014) Ruben K. Dagda et al.   Autophagy

Autophagy protects against hypoxic injury inC. elegans

(2014) Victor Samokhvalov et al.   Autophagy

Gangliosides protection against lysosomal pathology of synucleinopathies

(2014) Jianshe Wei et al.   Autophagy

Metabolic Activity Determines Efficacy of Macroautophagic Clearance of Pathological Oligomeric α-Synuclein

(2009) Wai Haung Yu et al.   AMERICAN JOURNAL OF PATHOLOGY

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Olomoucine inhibits cathepsin L nuclear translocation, activates autophagy and attenuates toxicity of 6-hydroxydopamine

(2009) Xi-Feng Fei et al.   BRAIN RESEARCH

LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model

(2009) Javier Alegre-Abarrategui et al.   HUMAN MOLECULAR GENETICS

Rapamycin protects against rotenone-induced apoptosis through autophagy induction

(2009) T. Pan et al.   NEUROSCIENCE

DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses

(2009) S. Vasseur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Neuronal Survival Factor MEF2D by Chaperone-Mediated Autophagy

(2009) Q. Yang et al.   SCIENCE

Autophagy: Principles and significance in health and disease

(2008) Virginia Todde et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Aberrant molecular properties shared by familial Parkinson’s disease-associated mutant UCH-L1 and carbonyl-modified UCH-L1

(2008) Tomohiro Kabuta et al.   HUMAN MOLECULAR GENETICS

Aberrant Interaction between Parkinson Disease-associated Mutant UCH-L1 and the Lysosomal Receptor for Chaperone-mediated Autophagy

(2008) Tomohiro Kabuta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and Macroautophagy in Neuronal Cells

(2008) Tereza Vogiatzi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells

(2008) Edward D. Plowey et al.   JOURNAL OF NEUROCHEMISTRY

Small molecule enhancers of autophagy for neurodegenerative diseases

(2008) Sovan Sarkar et al.   Molecular BioSystems

Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function

(2008) Cong Zhang et al.   NATURE MEDICINE