Fibrils of Truncated Pyroglutamyl-Modified Aβ Peptide Exhibit a Similar Structure as Wildtype Mature Aβ Fibrils
出版年份 2016 全文链接
标题
Fibrils of Truncated Pyroglutamyl-Modified Aβ Peptide Exhibit a Similar Structure as Wildtype Mature Aβ Fibrils
作者
关键词
-
出版物
Scientific Reports
Volume 6, Issue 1, Pages -
出版商
Springer Nature
发表日期
2016-09-21
DOI
10.1038/srep33531
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Enhanced Fibril Fragmentation of N-Terminally Truncated and Pyroglutamyl-Modified Aβ Peptides
- (2016) Melanie Wulff et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Amyloid-β Peptide Aβ3pE-42 Induces Lipid Peroxidation, Membrane Permeabilization, and Calcium Influx in Neurons
- (2015) Adam P. Gunn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Analysis and Aggregation Propensity of Pyroglutamate Aβ(3-40) in Aqueous Trifluoroethanol
- (2015) Christina Dammers et al. PLoS One
- Purification and Characterization of Recombinant N-Terminally Pyroglutamate-Modified Amyloid-β Variants and Structural Analysis by Solution NMR Spectroscopy
- (2015) Christina Dammers et al. PLoS One
- Significant Structural Differences between Transient Amyloid-β Oligomers and Less-Toxic Fibrils in Regions Known To Harbor Familial Alzheimer′s Mutations
- (2014) Bidyut Sarkar et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Atomic-Resolution Three-Dimensional Structure of Amyloid β Fibrils Bearing the Osaka Mutation
- (2014) Anne K. Schütz et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Pyroglutamylated Amyloid-β Peptide Reverses Cross β-Sheets by a Prion-Like Mechanism
- (2014) Jason O. Matos et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Local interactions influence the fibrillation kinetics, structure and dynamics of Aβ(1–40) but leave the general fibril structure unchanged
- (2014) Juliane Adler et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue
- (2013) Jun-Xia Lu et al. CELL
- Dual Acquisition Magic-Angle Spinning Solid-State NMR-Spectroscopy: Simultaneous Acquisition of Multidimensional Spectra of Biomacromolecules
- (2012) T. Gopinath et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Solid-state NMR Reveals a Close Structural Relationship between Amyloid-β Protofibrils and Oligomers
- (2012) Holger A. Scheidt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- N-Terminal pyroglutamate formation of Aβ38 and Aβ40 enforces oligomer formation and potency to disrupt hippocampal long-term potentiation
- (2012) Dagmar Schlenzig et al. JOURNAL OF NEUROCHEMISTRY
- Structural analysis of the pyroglutamate-modified isoform of the Alzheimer's disease-related amyloid-β using NMR spectroscopy
- (2012) Na Sun et al. JOURNAL OF PEPTIDE SCIENCE
- Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β
- (2012) Justin M. Nussbaum et al. NATURE
- NIH Image to ImageJ: 25 years of image analysis
- (2012) Caroline A Schneider et al. NATURE METHODS
- Solid-State NMR Spectroscopic Investigation of Aβ Protofibrils: Implication of a β-Sheet Remodeling upon Maturation into Terminal Amyloid Fibrils
- (2011) Holger A. Scheidt et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Solid-State NMR Studies of Amyloid Fibril Structure
- (2011) Robert Tycko Annual Review of Physical Chemistry
- Dynamics of Amyloid β Fibrils Revealed by Solid-state NMR
- (2011) Holger A. Scheidt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pyroglutamate Amyloid-β (Aβ): A Hatchet Man in Alzheimer Disease
- (2011) Sadim Jawhar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A New Structural Model of Aβ40Fibrils
- (2011) Ivano Bertini et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Conformational Flexibility of Y145Stop Human Prion Protein Amyloid Fibrils Probed by Solid-State Nuclear Magnetic Resonance Spectroscopy
- (2010) Jonathan J. Helmus et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils
- (2010) Mahiuddin Ahmed et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Stabilization of neurotoxic Alzheimer amyloid- oligomers by protein engineering
- (2010) A. Sandberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural and Dynamical Characterization of Fibrils from a Disease-Associated Alanine Expansion Domain Using Proteolysis and Solid-State NMR Spectroscopy
- (2008) Mirko Sackewitz et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Glutaminyl cyclase inhibition attenuates pyroglutamate Aβ and Alzheimer's disease–like pathology
- (2008) Stephan Schilling et al. NATURE MEDICINE
- Stabilization of a β-hairpin in monomeric Alzheimer's amyloid-β peptide inhibits amyloid formation
- (2008) Wolfgang Hoyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular structural basis for polymorphism in Alzheimer's -amyloid fibrils
- (2008) A. K. Paravastu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More