Amyloid-β Peptide Aβ3pE-42 Induces Lipid Peroxidation, Membrane Permeabilization, and Calcium Influx in Neurons
出版年份 2015 全文链接
标题
Amyloid-β Peptide Aβ3pE-42 Induces Lipid Peroxidation, Membrane Permeabilization, and Calcium Influx in Neurons
作者
关键词
-
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 291, Issue 12, Pages 6134-6145
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2016-03-18
DOI
10.1074/jbc.m115.655183
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Astrocytes and microglia but not neurons preferentially generate N-terminally truncated Aβ peptides
- (2015) Timo Jan Oberstein et al. NEUROBIOLOGY OF DISEASE
- Brain Amyloid-Beta Fragment Signatures in Pathological Ageing and Alzheimer's Disease by Hybrid Immunoprecipitation Mass Spectrometry
- (2015) Erik Portelius et al. Neurodegenerative Diseases
- Do current therapeutic anti-Aβ antibodies for Alzheimer’s disease engage the target?
- (2014) Andrew D. Watt et al. ACTA NEUROPATHOLOGICA
- Pyroglutamylated amyloid-β is associated with hyperphosphorylated tau and severity of Alzheimer’s disease
- (2014) Markus Mandler et al. ACTA NEUROPATHOLOGICA
- Role of the Fast Kinetics of Pyroglutamate-Modified Amyloid-β Oligomers in Membrane Binding and Membrane Permeability
- (2014) Joon Lee et al. BIOCHEMISTRY
- Activity and Architecture of Pyroglutamate-Modified Amyloid-β (AβpE3-42) Pores
- (2014) Alan L. Gillman et al. JOURNAL OF PHYSICAL CHEMISTRY B
- N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits
- (2013) Yvonne Bouter et al. ACTA NEUROPATHOLOGICA
- Abeta, oxidative stress in Alzheimer disease: Evidence based on proteomics studies
- (2013) Aaron M. Swomley et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- A central role for dityrosine crosslinking of Amyloid-β in Alzheimer’s disease
- (2013) Youssra K Al-Hilaly et al. Acta Neuropathologica Communications
- Intracellular accumulation of aggregated pyroglutamate amyloid beta: convergence of aging and Aβ pathology at the lysosome
- (2012) Line De Kimpe et al. AGE
- Copper Coordination to Native N-Terminally Modified versus Full-Length Amyloid-β: Second-Sphere Effects Determine the Species Present at Physiological pH
- (2012) Bruno Alies et al. INORGANIC CHEMISTRY
- Differential toxicity, conformation and morphology of typical initial aggregation states of Aβ1-42 and Aβpy3-42 beta-amyloids
- (2012) Denise Galante et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- The Metalloprotease Meprin β Generates Amino Terminal-truncated Amyloid β Peptide Species
- (2012) Jessica Bien et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pyroglutamate Amyloid β (Aβ) Aggravates Behavioral Deficits in Transgenic Amyloid Mouse Model for Alzheimer Disease
- (2012) Jessica L. Wittnam et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- N-Terminal pyroglutamate formation of Aβ38 and Aβ40 enforces oligomer formation and potency to disrupt hippocampal long-term potentiation
- (2012) Dagmar Schlenzig et al. JOURNAL OF NEUROCHEMISTRY
- A Reversible Early Oxidized Redox State That Precedes Macromolecular ROS Damage in Aging Nontransgenic and 3xTg-AD Mouse Neurons
- (2012) D. Ghosh et al. JOURNAL OF NEUROSCIENCE
- Structural analysis of the pyroglutamate-modified isoform of the Alzheimer's disease-related amyloid-β using NMR spectroscopy
- (2012) Na Sun et al. JOURNAL OF PEPTIDE SCIENCE
- Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β
- (2012) Justin M. Nussbaum et al. NATURE
- A neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptors
- (2012) H. You et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Amyloid beta peptide 1–42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures
- (2011) I.L. Ferreira et al. CELL CALCIUM
- Selective Hippocampal Neurodegeneration in Transgenic Mice Expressing Small Amounts of Truncated A Is Induced by Pyroglutamate-A Formation
- (2011) A. Alexandru et al. JOURNAL OF NEUROSCIENCE
- Pyroglutamate-Aβ 3 and 11 colocalize in amyloid plaques in Alzheimer's disease cerebral cortex with pyroglutamate-Aβ 11 forming the central core
- (2011) Christopher P. Sullivan et al. NEUROSCIENCE LETTERS
- Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer’s disease
- (2010) Erik Portelius et al. ACTA NEUROPATHOLOGICA
- Oxidative Stress in the Progression of Alzheimer Disease in the Frontal Cortex
- (2010) Mubeen A. Ansari et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Alzheimer's Aβ Peptides with Disease-Associated N-Terminal Modifications: Influence of Isomerisation, Truncation and Mutation on Cu2+ Coordination
- (2010) Simon C. Drew et al. PLoS One
- Biological metals and Alzheimer's disease: Implications for therapeutics and diagnostics
- (2010) James A. Duce et al. PROGRESS IN NEUROBIOLOGY
- Intraneuronal pyroglutamate-Abeta 3–42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model
- (2009) Oliver Wirths et al. ACTA NEUROPATHOLOGICA
- Pyroglutamate Formation Influences Solubility and Amyloidogenicity of Amyloid Peptides
- (2009) Dagmar Schlenzig et al. BIOCHEMISTRY
- N-terminal truncated pyroglutamyl β amyloid peptide Aβpy3-42 shows a faster aggregation kinetics than the full-length Aβ1-42
- (2009) Cristina D'Arrigo et al. BIOPOLYMERS
- The Caenorhabditis elegans Aβ1–42Model of Alzheimer Disease Predominantly Expresses Aβ3–42
- (2009) Gawain McColl et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amyloid-beta peptide Aβp3-42 affects early aggregation of full-length Aβ1-42
- (2009) Hiromi M. Sanders et al. PEPTIDES
- Amyloidogenic Processing of Amyloid Precursor Protein: Evidence of a Pivotal Role of Glutaminyl Cyclase in Generation of Pyroglutamate-Modified Amyloid-β†
- (2008) Holger Cynis et al. BIOCHEMISTRY
- Malondialdehyde, carbonyl proteins and albumin-disulphide as useful oxidative markers in mild cognitive impairment and Alzheimer's disease
- (2008) J. Greilberger et al. FREE RADICAL RESEARCH
- Glutaminyl cyclase inhibition attenuates pyroglutamate Aβ and Alzheimer's disease–like pathology
- (2008) Stephan Schilling et al. NATURE MEDICINE
- Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial Aβ
- (2008) Paul A. Adlard et al. NEURON
- N-truncated amyloid-β oligomers induce learning impairment and neuronal apoptosis
- (2007) Ihsen Youssef et al. NEUROBIOLOGY OF AGING
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started