标题
β-lactam/β-lactamase inhibitor combinations: an update
作者
关键词
-
出版物
MedChemComm
Volume 9, Issue 9, Pages 1439-1456
出版商
Royal Society of Chemistry (RSC)
发表日期
2018-08-17
DOI
10.1039/c8md00342d
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Meropenem/Vaborbactam, the First Carbapenem/β-Lactamase Inhibitor Combination
- (2018) Jonathan C. Cho et al. ANNALS OF PHARMACOTHERAPY
- Discovery of a Novel Metallo-β-Lactamase Inhibitor That Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacteriaceae
- (2018) Martin Everett et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Comparative In Vitro Activity of Omadacycline against Dog and Cat Bite Wound Isolates
- (2018) Ellie J. C. Goldstein et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Structural and Kinetic Studies of the Potent Inhibition of Metallo-β-lactamases by 6-Phosphonomethylpyridine-2-carboxylates
- (2018) Philip Hinchliffe et al. BIOCHEMISTRY
- Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-β-lactamases
- (2018) Dong Zhang et al. BIOORGANIC & MEDICINAL CHEMISTRY
- NOTA analogue: A first dithiocarbamate inhibitor of metallo-β-lactamases
- (2018) En Zhang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Atomic-Resolution Structure of a Class C β-Lactamase and Its Complex with Avibactam
- (2018) Cecilia Pozzi et al. ChemMedChem
- First identification of isatin- β -thiosemicarbazones as novel inhibitors of New Delhi metallo- β -lactamase-1: Chemical synthesis, biological evaluation and molecular simulation
- (2018) Guo-Qing Song et al. CHINESE CHEMICAL LETTERS
- Meropenem-vaborbactam: a carbapenem and beta-lactamase inhibitor with activity against carbapenem-resistant Enterobacteriaceae
- (2018) Young R. Lee et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- (( S )-3-Mercapto-2-methylpropanamido)acetic acid derivatives as metallo-β-lactamase inhibitors: Synthesis, kinetic and crystallographic studies
- (2018) Sha Liu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Emerging Gram negative resistance to last-line antimicrobial agents fosfomycin, colistin and ceftazidime-avibactam – epidemiology, laboratory detection and treatment implications
- (2018) Norelle Sherry et al. Expert Review of Anti-Infective Therapy
- Ceftolozane/tazobactam: place in therapy
- (2018) Daniele Roberto Giacobbe et al. Expert Review of Anti-Infective Therapy
- Effect of Meropenem-Vaborbactam vs Piperacillin-Tazobactam on Clinical Cure or Improvement and Microbial Eradication in Complicated Urinary Tract Infection
- (2018) Keith S. Kaye et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- In vitro activity of imipenem/relebactam against Gram-negative ESKAPE pathogens isolated in 17 European countries: 2015 SMART surveillance programme
- (2018) James A Karlowsky et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using β-Lactamase Inhibitors and β-Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234
- (2018) Krisztina M. Papp-Wallace et al. JOURNAL OF MEDICINAL CHEMISTRY
- In Silico Fragment-Based Design Identifies Subfamily B1 Metallo-β-lactamase Inhibitors
- (2018) Ricky Cain et al. JOURNAL OF MEDICINAL CHEMISTRY
- Meropenem and Vaborbactam: Stepping up the Battle against Carbapenem-resistant Enterobacteriaceae
- (2018) Sarah Christina Jane Jorgensen et al. PHARMACOTHERAPY
- The Continuing Challenge of Metallo-β-Lactamase Inhibition: Mechanism Matters
- (2018) Lin-Cheng Ju et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Rhodanine as a Potent Scaffold for the Development of Broad-Spectrum Metallo-β-lactamase Inhibitors
- (2018) Yang Xiang et al. ACS Medicinal Chemistry Letters
- Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitors
- (2018) Runming Wang et al. Nature Communications
- Exploring Additional Dimensions of Complexity in Inhibitor Design for Serine β-Lactamases: Mechanistic and Intra- and Inter-molecular Chemistry Approaches
- (2018) Focco van den Akker et al. Frontiers in Microbiology
- Antibacterial Drug Discovery: Some Assembly Required
- (2018) Rubén Tommasi et al. ACS Infectious Diseases
- Vancomycin Analogue Restores Meropenem Activity against NDM-1 Gram-Negative Pathogens
- (2018) Venkateswarlu Yarlagadda et al. ACS Infectious Diseases
- Past and Present Perspectives on β-Lactamases
- (2018) Karen Bush ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Diversity and Proliferation of Metallo-β-Lactamases: a Clarion Call for Clinically Effective Metallo-β-Lactamase Inhibitors
- (2018) Anou M. Somboro et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Structure-activity relationship study and optimisation of 2-aminopyrrole-1-benzyl-4,5-diphenyl-1 H -pyrrole-3-carbonitrile as a broad spectrum metallo-β-lactamase inhibitor
- (2017) Ross P. McGeary et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Metallo-β-lactamase inhibitors by bioisosteric replacement: Preparation, activity and binding
- (2017) Susann Skagseth et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Using β-lactam/β-lactamase inhibitors for infections due to extended-spectrum β-lactamase-producing Enterobacteriaceae to slow the emergence of carbapenem-resistant Enterobacteriaceae
- (2017) Richard R. Watkins et al. Expert Review of Anti-Infective Therapy
- Burden of antimicrobial resistance in an era of decreasing susceptibility
- (2017) Glenn S. Tillotson et al. Expert Review of Anti-Infective Therapy
- Progress toward inhibitors of metallo-β-lactamases
- (2017) Ross P McGeary et al. Future Medicinal Chemistry
- Prospective, randomized, double-blind, Phase 2 dose-ranging study comparing efficacy and safety of imipenem/cilastatin plus relebactam with imipenem/cilastatin alone in patients with complicated urinary tract infections
- (2017) Matthew Sims et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- WCK 5222 (cefepime/zidebactam) antimicrobial activity tested against Gram-negative organisms producing clinically relevant β-lactamases
- (2017) Helio S. Sader et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-β-lactamase-1
- (2017) Allie Y. Chen et al. JOURNAL OF MEDICINAL CHEMISTRY
- Total Syntheses of Natural Metallophores Staphylopine and Aspergillomarasmine A
- (2017) Jian Zhang et al. JOURNAL OF ORGANIC CHEMISTRY
- Oligopeptides as full-length New Delhi metallo-β-lactamase-1 (NDM-1) inhibitors
- (2017) Bingzheng Shen et al. PLoS One
- Exploring the potential of boronic acids as inhibitors of OXA-24/40 β-lactamase
- (2017) Josephine P. Werner et al. PROTEIN SCIENCE
- NMR-filtered virtual screening leads to non-metal chelating metallo-β-lactamase inhibitors
- (2017) Guo-Bo Li et al. Chemical Science
- Carbamylmethyl Mercaptoacetate Thioether: A Novel Scaffold for the Development of L1 Metallo-β-lactamase Inhibitors
- (2017) Ya-Nan Chang et al. ACS Medicinal Chemistry Letters
- Acinetobacter baumannii OmpA Is a Selective Antibiotic Permeant Porin
- (2017) Ramkumar Iyer et al. ACS Infectious Diseases
- Thiol-Containing Metallo-β-Lactamase Inhibitors Resensitize Resistant Gram-Negative Bacteria to Meropenem
- (2017) Kamaleddin Haj Mohammad Ebrahim Tehrani et al. ACS Infectious Diseases
- Structure-Based Analysis of Boronic Acids as Inhibitors of Acinetobacter-Derived Cephalosporinase-7, a Unique Class C β-Lactamase
- (2017) Alexandra A. Bouza et al. ACS Infectious Diseases
- Reversibility of Covalent, Broad-Spectrum Serine β-Lactamase Inhibition by the Diazabicyclooctenone ETX2514
- (2017) Adam B. Shapiro et al. ACS Infectious Diseases
- Probing the Interaction of Aspergillomarasmine A with Metallo-β-lactamases NDM-1, VIM-2, and IMP-7
- (2017) Alexander Bergstrom et al. ACS Infectious Diseases
- Challenges in the Development of a Thiol-Based Broad-Spectrum Inhibitor for Metallo-β-Lactamases
- (2017) Dominik Büttner et al. ACS Infectious Diseases
- Game Changers: New β-Lactamase Inhibitor Combinations Targeting Antibiotic Resistance in Gram-Negative Bacteria
- (2017) Karen Bush ACS Infectious Diseases
- ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii
- (2017) Thomas F. Durand-Réville et al. Nature Microbiology
- Total Synthesis of Aspergillomarasmine A and Related Compounds: A Sulfamidate Approach Enables Exploration of Structure-Activity Relationships
- (2016) Silvia A. Albu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of the β-Lactamase Inhibitor Vaborbactam (RPX7009) in Healthy Adult Subjects
- (2016) David C. Griffith et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Phase 2, Dose-Ranging Study of Relebactam with Imipenem-Cilastatin in Subjects with Complicated Intra-abdominal Infection
- (2016) Christopher Lucasti et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Crystal Structures of KPC-2 and SHV-1 β-Lactamases in Complex with the Boronic Acid Transition State Analog S02030
- (2016) Nhu Q. Nguyen et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- In VitroandIn VivoActivities of OP0595, a New Diazabicyclooctane, against CTX-M-15-Positive Escherichia coli and KPC-Positive Klebsiella pneumoniae
- (2016) Akihiro Morinaka et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- In VitroEvaluation of the Activity of Imipenem-Relebactam against 451 Recent Clinical Isolates of Bacteroides Group and Related Species
- (2016) David R. Snydman et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Effect of the β-Lactamase Inhibitor Vaborbactam Combined with Meropenem against Serine Carbapenemase-Producing Enterobacteriaceae
- (2016) Mariana Castanheira et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Discovery of a novel covalent non-β-lactam inhibitor of the metallo-β-lactamase NDM-1
- (2016) Tony Christopeit et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Captopril analogues as metallo-β-lactamase inhibitors
- (2016) Yusralina Yusof et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Optimization of amino acid thioesters as inhibitors of metallo-β-lactamase L1
- (2016) Xiao-Long Liu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Ceftazidime-avibactam Versus Doripenem for the Treatment of Complicated Urinary Tract Infections, Including Acute Pyelonephritis: RECAPTURE, a Phase 3 Randomized Trial Program
- (2016) Florian M. Wagenlehner et al. CLINICAL INFECTIOUS DISEASES
- Efficacy and Safety of Ceftazidime-Avibactam Plus Metronidazole Versus Meropenem in the Treatment of Complicated Intra-abdominal Infection: Results From a Randomized, Controlled, Double-Blind, Phase 3 Program
- (2016) John E. Mazuski et al. CLINICAL INFECTIOUS DISEASES
- Emergence of antimicrobial resistance among Acinetobacter species
- (2016) Nina M. Clark et al. Current Opinion in Critical Care
- Ceftolozane/Tazobactam: A Review in Complicated Intra-Abdominal and Urinary Tract Infections
- (2016) Lesley J. Scott DRUGS
- Design, synthesis, and in vitro and biological evaluation of potent amino acid-derived thiol inhibitors of the metallo-β-lactamase IMP-1
- (2016) Omid Khalili Arjomandi et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- New Delhi metallo-β-lactamase-1: structure, inhibitors and detection of producers
- (2016) Paul W Groundwater et al. Future Medicinal Chemistry
- In vitro and in vivo activities of the diazabicyclooctane OP0595 against AmpC-derepressed Pseudomonas aeruginosa
- (2016) Akihiro Morinaka et al. JOURNAL OF ANTIBIOTICS
- LN-1-255, a penicillanic acid sulfone able to inhibit the class D carbapenemase OXA-48
- (2016) Juan A. Vallejo et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- In vitroevaluation of metal chelators as potential metallo- β -lactamase inhibitors
- (2016) R. Azumah et al. JOURNAL OF APPLIED MICROBIOLOGY
- Targeting clinically-relevant metallo-β-lactamases: from high-throughput docking to broad-spectrum inhibitors
- (2016) Margherita Brindisi et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Ceftazidime-avibactam or best available therapy in patients with ceftazidime-resistant Enterobacteriaceae and Pseudomonas aeruginosa complicated urinary tract infections or complicated intra-abdominal infections (REPRISE): a randomised, pathogen-directed, phase 3 study
- (2016) Yehuda Carmeli et al. LANCET INFECTIOUS DISEASES
- Development of a Manufacturing Route to Avibactam, a β-Lactamase Inhibitor
- (2016) Matthew Ball et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Synthesis and inhibitory activity of acetamidophosphonic acids against metallo-β-lactamases
- (2016) Yi-Lin Zhang et al. PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
- Cross-class metallo-β-lactamase inhibition by bisthiazolidines reveals multiple binding modes
- (2016) Philip Hinchliffe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In vitro and in vivo activity of ML302F: a thioenolate inhibitor of VIM-subfamily metallo β-lactamases
- (2016) Jonathan W. Betts et al. MedChemComm
- Recent advances in the rational design and optimization of antibacterial agents
- (2016) Jesse A. Jones et al. MedChemComm
- Triazolylthioacetamide: A Valid Scaffold for the Development of New Delhi Metallo-β-Lactmase-1 (NDM-1) Inhibitors
- (2016) Le Zhai et al. ACS Medicinal Chemistry Letters
- Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates
- (2016) Jürgen Brem et al. Nature Communications
- The global epidemiology of carbapenemase-producing Enterobacteriaceae
- (2016) David van Duin et al. Virulence
- Total Synthesis and Activity of the Metallo-β-lactamase Inhibitor Aspergillomarasmine A
- (2015) Kalinka Koteva et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Total Synthesis and Structural Reassignment of Aspergillomarasmine A
- (2015) Daohong Liao et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Ceftolozane/Tazobactam
- (2015) Allana J. Sucher et al. ANNALS OF PHARMACOTHERAPY
- Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers
- (2015) Jürgen Brem et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Activity of Imipenem with Relebactam against Gram-Negative Pathogens from New York City
- (2015) Amabel Lapuebla et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- In VivoActivities of Simulated Human Doses of Cefepime and Cefepime-AAI101 against Multidrug-Resistant Gram-Negative Enterobacteriaceae
- (2015) Jared L. Crandon et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Ceftazidime-Avibactam Activity Tested against Enterobacteriaceae Isolates from U.S. Hospitals (2011 to 2013) and Characterization of β-Lactamase-Producing Strains
- (2015) Mariana Castanheira et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Interactions of OP0595, a Novel Triple-Action Diazabicyclooctane, with β-Lactams against OP0595-Resistant Enterobacteriaceae Mutants
- (2015) David M. Livermore et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Ebselen as a potent covalent inhibitor of New Delhi metallo-β-lactamase (NDM-1)
- (2015) Jiachi Chiou et al. CHEMICAL COMMUNICATIONS
- Ceftolozane/Tazobactam Plus Metronidazole for Complicated Intra-abdominal Infections in an Era of Multidrug Resistance: Results From a Randomized, Double-Blind, Phase 3 Trial (ASPECT-cIAI)
- (2015) Joseph Solomkin et al. CLINICAL INFECTIOUS DISEASES
- Emerging broad-spectrum resistance in Pseudomonas aeruginosa and Acinetobacter baumannii : Mechanisms and epidemiology
- (2015) Anaïs Potron et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Ceftolozane/tazobactam and ceftazidime/avibactam: two novel β-lactam/β-lactamase inhibitor combination agents for the treatment of resistant Gram-negative bacterial infections
- (2015) Jordan L. Liscio et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- NOTA: a potent metallo-β-lactamase inhibitor
- (2015) Anou M. Somboro et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Activity of OP0595/β-lactam combinations against Gram-negative bacteria with extended-spectrum, AmpC and carbapenem-hydrolysing β-lactamases
- (2015) David M. Livermore et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Pharmacokinetics/pharmacodynamics of a β-lactam and β-lactamase inhibitor combination: a novel approach for aztreonam/avibactam
- (2015) Renu Singh et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- OP0595, a new diazabicyclooctane: mode of action as a serine β-lactamase inhibitor, antibiotic and β-lactam ‘enhancer’
- (2015) Akihiro Morinaka et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Approved Drugs Containing Thiols as Inhibitors of Metallo-β-lactamases: Strategy To Combat Multidrug-Resistant Bacteria
- (2015) Franca-M. Klingler et al. JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of a Cyclic Boronic Acid β-Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases
- (2015) Scott J. Hecker et al. JOURNAL OF MEDICINAL CHEMISTRY
- Ceftolozane-tazobactam compared with levofloxacin in the treatment of complicated urinary-tract infections, including pyelonephritis: a randomised, double-blind, phase 3 trial (ASPECT-cUTI)
- (2015) Florian M Wagenlehner et al. LANCET
- Identification and Validation Novel of VIM-2 Metallo-β-lactamase Tripeptide Inhibitors
- (2015) Jing Xiao et al. Molecular Informatics
- Ceftolozane/Tazobactam: A Novel Cephalosporin/β-Lactamase Inhibitor Combination
- (2015) Jonathan C. Cho et al. PHARMACOTHERAPY
- Azolylthioacetamide: A Highly Promising Scaffold for the Development of Metallo-β-lactamase Inhibitors
- (2015) Shao-Kang Yang et al. ACS Medicinal Chemistry Letters
- Amino Acid Thioester Derivatives: A Highly Promising Scaffold for the Development of Metallo-β-lactamase L1 Inhibitors
- (2015) Xiao-Long Liu et al. ACS Medicinal Chemistry Letters
- Bisthiazolidines: A Substrate-Mimicking Scaffold as an Inhibitor of the NDM-1 Carbapenemase
- (2015) Mariano M. González et al. ACS Infectious Diseases
- In VitroSusceptibility of Characterized β-Lactamase-Producing Strains Tested with Avibactam Combinations
- (2014) Henry Li et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Avibactam and Class C β-Lactamases: Mechanism of Inhibition, Conservation of the Binding Pocket, and Implications for Resistance
- (2014) S. D. Lahiri et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Unexpected Challenges in Treating Multidrug-Resistant Gram-Negative Bacteria: Resistance to Ceftazidime-Avibactam in Archived Isolates of Pseudomonas aeruginosa
- (2014) Marisa L. Winkler et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Biochemical and Structural Analysis of Inhibitors Targeting the ADC-7 Cephalosporinase of Acinetobacter baumannii
- (2014) Rachel A. Powers et al. BIOCHEMISTRY
- X-ray crystallographic analysis of IMP-1 metallo-β-lactamase complexed with a 3-aminophthalic acid derivative, structure-based drug design, and synthesis of 3,6-disubstituted phthalic acid derivative inhibitors
- (2014) Yukiko Hiraiwa et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Covalent Inhibition of New Delhi Metallo-β-Lactamase-1 (NDM-1) by Cefaclor
- (2014) Pei W. Thomas et al. CHEMBIOCHEM
- Diaryl-Substituted Azolylthioacetamides: Inhibitor Discovery of New Delhi Metallo-β-Lactamase-1 (NDM-1)
- (2014) Yi-Lin Zhang et al. ChemMedChem
- Ceftazidime/avibactam activity tested against Gram-negative bacteria isolated from bloodstream, pneumonia, intra-abdominal and urinary tract infections in US medical centres (2012)
- (2014) R. K. Flamm et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- New Delhi Metallo-β-Lactamase (NDM-1): An Updates
- (2014) S. Shakil et al. JOURNAL OF CHEMOTHERAPY
- Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance
- (2014) Andrew M. King et al. NATURE
- Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition
- (2014) Jürgen Brem et al. Nature Chemistry
- In VitroActivities of Ceftazidime-Avibactam and Aztreonam-Avibactam against 372 Gram-Negative Bacilli Collected in 2011 and 2012 from 11 Teaching Hospitals in China
- (2013) Xiaojuan Wang et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- In VitroActivity of Ceftolozane-Tazobactam against Pseudomonas aeruginosa Isolates Obtained from Patients in Canadian Hospitals in the CANWARD Study, 2007 to 2012
- (2013) A. Walkty et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Antimicrobial Activity of Ceftolozane-Tazobactam Tested against Enterobacteriaceae and Pseudomonas aeruginosa with Various Resistance Patterns Isolated in U.S. Hospitals (2011-2012)
- (2013) David J. Farrell et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Activity of Ceftolozane-Tazobactam against a Broad Spectrum of Recent Clinical Anaerobic Isolates
- (2013) David R. Snydman et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC β-Lactamases
- (2013) Sushmita D. Lahiri et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Contemporary Diversity of β-Lactamases among Enterobacteriaceae in the Nine U.S. Census Regions and Ceftazidime-Avibactam Activity Tested against Isolates Producing the Most Prevalent β-Lactamase Groups
- (2013) Mariana Castanheira et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Antimicrobial Activity of Ceftazidime-Avibactam against Gram-Negative Organisms Collected from U.S. Medical Centers in 2012
- (2013) Helio S. Sader et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Metallo-β-lactamase: Inhibitors and reporter substrates
- (2013) Walter Fast et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Simplified captopril analogues as NDM-1 inhibitors
- (2013) Ningning Li et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Metallo-β-Lactamases: Structural Features, Antibiotic Recognition, Inhibition, and Inhibitor Design
- (2013) Jing-Fang Wang et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Ceftolozane/Tazobactam: A Novel Cephalosporin/β-Lactamase Inhibitor Combination with Activity Against Multidrug-Resistant Gram-Negative Bacilli
- (2013) George G. Zhanel et al. DRUGS
- Targeting metallo-β-lactamase enzymes in antibiotic resistance
- (2013) Dustin T King et al. Future Medicinal Chemistry
- Kinetics of Avibactam Inhibition against Class A, C, and D β-Lactamases
- (2013) David E. Ehmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Global spread of antibiotic resistance: the example of New Delhi metallo-β-lactamase (NDM)-mediated carbapenem resistance
- (2013) Alan P. Johnson et al. JOURNAL OF MEDICAL MICROBIOLOGY
- Activity of Ceftaroline-Avibactam Tested against Gram-Negative Organism Populations, including Strains Expressing One or More β-Lactamases and Methicillin-Resistant Staphylococcus aureus Carrying Various Staphylococcal Cassette ChromosomemecTypes
- (2012) Mariana Castanheira et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- In VitroAntibacterial Activity of the Ceftazidime-Avibactam (NXL104) Combination against Pseudomonas aeruginosa Clinical Isolates
- (2012) Premavathy Levasseur et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- N-Heterocyclic dicarboxylic acids: Broad-spectrum inhibitors of metallo-β-lactamases with co-antibacterial effect against antibiotic-resistant bacteria
- (2012) Lei Feng et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Efficacy and safety of ceftazidime–avibactam versus imipenem–cilastatin in the treatment of complicated urinary tract infections, including acute pyelonephritis, in hospitalized adults: results of a prospective, investigator-blinded, randomized study
- (2012) José A. Vazquez et al. CURRENT MEDICAL RESEARCH AND OPINION
- Evaluation of Double-Disk Potentiation and Disk Potentiation Tests Using Dipicolinic Acid for Detection of Metallo- -Lactamase-Producing Pseudomonas spp. and Acinetobacter spp.
- (2012) D. Yong et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Kinetic characterization of a slow-binding inhibitor of Bla2: thiomaltol
- (2012) Sara R. Schlesinger et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Avibactam is a covalent, reversible, non- -lactam -lactamase inhibitor
- (2012) D. E. Ehmann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A simple test for the detection of KPC and metallo-β-lactamase carbapenemase-producing Pseudomonas aeruginosa isolates with the use of meropenem disks supplemented with aminophenylboronic acid, dipicolinic acid and cloxacillin
- (2011) F. Pasteran et al. CLINICAL MICROBIOLOGY AND INFECTION
- In vitro activity of avibactam (NXL104) in combination with β-lactams against Gram-negative bacteria, including OXA-48 β-lactamase-producing Klebsiella pneumoniae
- (2011) Z. Aktaş et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Novel Insights into the Mode of Inhibition of Class A SHV-1 β-Lactamases Revealed by Boronic Acid Transition State Inhibitors
- (2010) Wei Ke et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Penicillin Sulfone Inhibitors of Class D -Lactamases
- (2010) S. M. Drawz et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Three Decades of -Lactamase Inhibitors
- (2010) S. M. Drawz et al. CLINICAL MICROBIOLOGY REVIEWS
- Chequerboard titration of cephalosporin CXA-101 (FR264205) and tazobactam versus -lactamase-producing Enterobacteriaceae
- (2010) D. M. Livermore et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Boronic acids in medicinal chemistry: anticancer, antibacterial and antiviral applications
- (2010) Paul C. Trippier et al. MedChemComm
- Synthesis and SAR of novel parenteral anti-pseudomonal cephalosporins: Discovery of FR264205
- (2008) Ayako Toda et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Dipicolinic acid-based disk methods for detection of metallo-β-lactamase–producing Pseudomonas spp. and Acinetobacter spp.
- (2008) Kyeong Seob Shin et al. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
- Strategic Design of an Effective β-Lactamase Inhibitor
- (2008) Priyaranjan Pattanaik et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural requirements for the stability of novel cephalosporins to AmpC β-lactamase based on 3D-structure
- (2007) Kenji Murano et al. BIOORGANIC & MEDICINAL CHEMISTRY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search