LN-1-255, a penicillanic acid sulfone able to inhibit the class D carbapenemase OXA-48

Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study

(2016) Yi-Yun Liu et al.   LANCET INFECTIOUS DISEASES

Variants of β-Lactamase KPC-2 That Are Resistant to Inhibition by Avibactam

(2015) Krisztina M. Papp-Wallace et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Correlation of β-Lactamase Production and Colistin Resistance among Enterobacteriaceae Isolates from a Global Surveillance Program

(2015) Patricia A. Bradford et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Molecular epidemiology of carbapenemase-producing Klebsiella pneumoniae in a hospital in Madrid: Successful establishment of an OXA-48 ST11 clone

(2015) Patricia Brañas et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Molecular Basis of Selective Inhibition and Slow Reversibility of Avibactam against Class D Carbapenemases: A Structure-Guided Study of OXA-24 and OXA-48

(2014) Sushmita D. Lahiri et al.   ACS Chemical Biology

The difficult-to-control spread of carbapenemase producers among Enterobacteriaceae worldwide

(2014) P. Nordmann et al.   CLINICAL MICROBIOLOGY AND INFECTION

Evolution of carbapenemase-producing Enterobacteriaceae at the global and national level: What should be expected in the future?

(2014) Jesús Oteo et al.   ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA

New β-Lactamase Inhibitors: a Therapeutic Renaissance in an MDR World

(2013) Sarah M. Drawz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Ceftazidime-Avibactam: a Novel Cephalosporin/β-lactamase Inhibitor Combination

(2013) George G. Zhanel et al.   DRUGS

Carbapenemase-producing Enterobacteriaceae in Europe: a survey among national experts from 39 countries, February 2013

(2013) C Glasner et al.   Eurosurveillance

Screening and deciphering antibiotic resistance inAcinetobacter baumannii: a state of the art

(2013) Rémy A Bonnin et al.   Expert Review of Anti-Infective Therapy

A kinetic analysis of the inhibition of FOX-4  -lactamase, a plasmid-mediated AmpC cephalosporinase, by monocyclic  -lactams and carbapenems

(2013) K. M. Papp-Wallace et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Dissemination of carbapenemase-producing Enterobacteriaceae in France, 2012

(2013) L. Dortet et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Kinetics of Avibactam Inhibition against Class A, C, and D β-Lactamases

(2013) David E. Ehmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapid evolution and spread of carbapenemases among Enterobacteriaceae in Europe

(2012) R. Cantón et al.   CLINICAL MICROBIOLOGY AND INFECTION

OXA-48-like carbapenemases: the phantom menace

(2012) L. Poirel et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Avibactam is a covalent, reversible, non- -lactam  -lactamase inhibitor

(2012) D. E. Ehmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploring the Inhibition of CTX-M-9 by β-Lactamase Inhibitors and Carbapenems

(2011) Christopher R. Bethel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Role ofKlebsiella pneumoniaeLamB Porin in Antimicrobial Resistance

(2011) Laura García-Sureda et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genetic Features of the Widespread Plasmid Coding for the Carbapenemase OXA-48

(2011) Laurent Poirel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

OXA-163, an OXA-48-Related Class D β-Lactamase with Extended Activity Toward Expanded-Spectrum Cephalosporins

(2011) Laurent Poirel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

First Outbreak of a Plasmid-Mediated Carbapenem-Hydrolyzing OXA-48 β-Lactamase in Klebsiella pneumoniae in Spain

(2011) Cristina Pitart et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

European dissemination of a single OXA-48-producing Klebsiella pneumoniae clone

(2011) A. Potron et al.   CLINICAL MICROBIOLOGY AND INFECTION

Therapeutic options for infections withEnterobacteriaceaeproducing carbapenem-hydrolyzing enzymes

(2011) Matthew E Falagas et al.   Future Microbiology

False extended-spectrum β-lactamase phenotype in clinical isolates of Escherichia coli associated with increased expression of OXA-1 or TEM-1 penicillinases and loss of porins

(2011) Alejandro Beceiro et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Evolution to carbapenem-hydrolyzing activity in noncarbapenemase class D  -lactamase OXA-10 by rational protein design

(2011) F. De Luca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Penicillin Sulfone Inhibitors of Class D  -Lactamases

(2010) S. M. Drawz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Extended-spectrum β-lactamase producing Escherichia coli: changing epidemiology and clinical impact

(2010) Jesús Oteo et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Emerging carbapenemases: a global perspective

(2010) Timothy R. Walsh   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Design, Synthesis, and Crystal Structures of 6-Alkylidene-2′-Substituted Penicillanic Acid Sulfones as Potent Inhibitors ofAcinetobacter baumanniiOXA-24 Carbapenemase

(2010) German Bou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diversity, Epidemiology, and Genetics of Class D  -Lactamases

(2009) L. Poirel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Updated Functional Classification of  -Lactamases

(2009) K. Bush et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Crystal Structure of the OXA-48 β-Lactamase Reveals Mechanistic Diversity among Class D Carbapenemases

(2009) Jean-Denis Docquier et al.   CHEMISTRY & BIOLOGY

β-Lactamase Inhibitors: The Story so Far

(2009) Francisco Perez-Llarena et al.   CURRENT MEDICINAL CHEMISTRY

Strategic Design of an Effective β-Lactamase Inhibitor

(2008) Priyaranjan Pattanaik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY