Identification and Validation Novel of VIM-2 Metallo-β-lactamase Tripeptide Inhibitors

Pharmacokinetics and Pharmacokinetic–Pharmacodynamic Correlations of Therapeutic Peptides

(2013) Lei Diao et al.   CLINICAL PHARMACOKINETICS

Computational Peptidology: A New and Promising Approach to Therapeutic Peptide Design

(2013) P. Zhou et al.   CURRENT MEDICINAL CHEMISTRY

Outbreak of metallo- -lactamase VIM-2-positive strains of Pseudomonas aeruginosa in the Ivory Coast

(2013) K. Jeannot et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Experimental versus predicted affinities for ligand binding to estrogen receptor: iterative selection and rescoring of docked poses systematically improves the correlation

(2013) James S. Wright et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Ligand-based pharmacophore modeling and Bayesian approaches to identify c-Src inhibitors

(2013) Sugunadevi Sakkiah et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Probiotics: A new way to fight bacterial pulmonary infections?

(2013) Y. Alexandre et al.   MEDECINE ET MALADIES INFECTIEUSES

β-Lactamase Inhibitors: An Update

(2013) Jiao Chen et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Inhibitor Discovery of Full-Length New Delhi Metallo-β-Lactamase-1 (NDM-1)

(2013) Bingzheng Shen et al.   PLoS One

Systematic Analysis of Metallo-β-Lactamases Using an Automated Database

(2012) Michael Widmann et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Metallo-β-lactamase-producing Pseudomonas aeruginosa in the Netherlands: the nationwide emergence of a single sequence type

(2012) A.K. Van der Bij et al.   CLINICAL MICROBIOLOGY AND INFECTION

VIM-2 metallo- -lactamase-producing Pseudomonas aeruginosa causing an outbreak in South Africa

(2012) R. K. Jacobson et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

First Report of an Extensively Drug-Resistant VIM-2 Metallo- -Lactamase-Producing Brevundimonas diminuta Clinical Isolate

(2012) M. N. Almuzara et al.   JOURNAL OF CLINICAL MICROBIOLOGY

New Delhi Metallo-β-Lactamase: Structural Insights into β-Lactam Recognition and Inhibition

(2012) Dustin T. King et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Docking-based 3D-QSAR modeling of the inhibitors of IMP metallo-β-lactamase

(2012) Jiao Chen et al.   MEDICINAL CHEMISTRY RESEARCH

Structure Based Design and Synthesis of Peptide Inhibitor of Human LOX-12: In Vitro and In Vivo Analysis of a Novel Therapeutic Agent for Breast Cancer

(2012) Abhay kumar Singh et al.   PLoS One

A rapid in situ procedure for determination of bacterial susceptibility or resistance to antibiotics that inhibit peptidoglycan biosynthesis

(2011) Rebeca Santiso et al.   BMC MICROBIOLOGY

Pharmacophore Modelling: A Forty Year Old Approach and its Modern Synergies

(2011) F. Caporuscio et al.   CURRENT MEDICINAL CHEMISTRY

Potential virtual lead identification in the discovery of renin inhibitors: Application of ligand and structure-based pharmacophore modeling approaches

(2011) Sundarapandian Thangapandian et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

First outbreak of VIM-2 metallo-β-lactamase-producing Pseudomonas aeruginosa in The Netherlands: microbiology, epidemiology and clinical outcomes

(2011) A.K. Van der Bij et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Modeling the interactions between polyoxometalates and their environment

(2011) Blandine Courcot et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Mimicking Peptides… In Silico

(2011) Matteo Floris et al.   Molecular Informatics

Mutational Analysis of VIM-2 Reveals an Essential Determinant for Metallo- -Lactamase Stability and Folding

(2010) L. Borgianni et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Ligand and structure based pharmacophore modeling to facilitate novel histone deacetylase 8 inhibitor design

(2010) Sundarapandian Thangapandian et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study

(2010) Karthikeyan K Kumarasamy et al.   LANCET INFECTIOUS DISEASES

NH-1,2,3-Triazole Inhibitors of the VIM-2 Metallo-β-Lactamase

(2010) Timo Weide et al.   ACS Medicinal Chemistry Letters

Approaches to the simultaneous inactivation of metallo- and serine-β-lactamases

(2009) Sudhakar Reddy Ganta et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery of Novel Myc−Max Heterodimer Disruptors with a Three-Dimensional Pharmacophore Model

(2009) Gabriela Mustata et al.   JOURNAL OF MEDICINAL CHEMISTRY

The generalized Born/volume integral implicit solvent model: Estimation of the free energy of hydration using London dispersion instead of atomic surface area

(2008) Paul Labute   JOURNAL OF COMPUTATIONAL CHEMISTRY