标题
The Human Blood Metabolome-Transcriptome Interface
作者
关键词
Metabolic pathways, Metabolic networks, Metabolites, Blood, Fatty acids, Metabolic processes, Lipid metabolism, Metabolomics
出版物
PLoS Genetics
Volume 11, Issue 6, Pages e1005274
出版商
Public Library of Science (PLoS)
发表日期
2015-06-19
DOI
10.1371/journal.pgen.1005274
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- SNiPA: an interactive, genetic variant-centered annotation browser
- (2014) Matthias Arnold et al. BIOINFORMATICS
- Mendelian randomization: genetic anchors for causal inference in epidemiological studies
- (2014) G. Davey Smith et al. HUMAN MOLECULAR GENETICS
- Linking diet, physical activity, cardiorespiratory fitness and obesity to serum metabolite networks: findings from a population-based study
- (2014) A Floegel et al. INTERNATIONAL JOURNAL OF OBESITY
- Genome metabolome integrated network analysis to uncover connections between genetic variants and complex traits: an application to obesity
- (2014) B. Valcarcel et al. Journal of the Royal Society Interface
- An atlas of genetic influences on human blood metabolites
- (2014) So-Youn Shin et al. NATURE GENETICS
- Lipid Metabolism, Oxidative Stress and Cell Death Are Regulated by PKC Delta in a Dietary Model of Nonalcoholic Steatohepatitis
- (2014) Michael W. Greene et al. PLoS One
- Mapping the Genetic Architecture of Gene Regulation in Whole Blood
- (2014) Katharina Schramm et al. PLoS One
- Contribution of Network Connectivity in Determining the Relationship between Gene Expression and Metabolite Concentration Changes
- (2014) Aleksej Zelezniak et al. PLoS Computational Biology
- An expression atlas of human primary cells: inference of gene function from coexpression networks
- (2013) Neil A Mabbott et al. BMC GENOMICS
- Controlling 2-arachidonoylglycerol metabolism as an anti-inflammatory strategy
- (2013) Mireille Alhouayek et al. DRUG DISCOVERY TODAY
- Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits
- (2013) Ann-Kristin Petersen et al. HUMAN MOLECULAR GENETICS
- A community-driven global reconstruction of human metabolism
- (2013) Ines Thiele et al. NATURE BIOTECHNOLOGY
- Molecular signatures of antibody responses derived from a systems biology study of five human vaccines
- (2013) Shuzhao Li et al. NATURE IMMUNOLOGY
- Systems genetics approaches to understand complex traits
- (2013) Mete Civelek et al. NATURE REVIEWS GENETICS
- JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles
- (2013) Anthony Mathelier et al. NUCLEIC ACIDS RESEARCH
- Endogenous cannabinoids revisited: A biochemistry perspective
- (2013) B.M. Fonseca et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Dysregulation of glucocorticoid receptor co-factors FKBP5, BAG1 and PTGES3 in prefrontal cortex in psychotic illness
- (2013) Duncan Sinclair et al. Scientific Reports
- CTen: a web-based platform for identifying enriched cell types from heterogeneous microarray data
- (2012) Jason E Shoemaker et al. BMC GENOMICS
- FAT SIGNALS - Lipases and Lipolysis in Lipid Metabolism and Signaling
- (2012) Rudolf Zechner et al. Cell Metabolism
- Metabolite Profiling Identifies Pathways Associated With Metabolic Risk in Humans
- (2012) Susan Cheng et al. CIRCULATION
- Long-term Leisure-time Physical Activity and Serum Metabolome
- (2012) Urho M. Kujala et al. CIRCULATION
- Cortisol modulates the expression of cytokines and suppressors of cytokine signaling (SOCS) in rainbow trout hepatocytes
- (2012) Anju M. Philip et al. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
- Glucocorticoids Modulate the mTOR Pathway in the Hippocampus: Differential Effects Depending on Stress History
- (2012) J. Annelies E. Polman et al. ENDOCRINOLOGY
- Network Analysis Reveals Centrally Connected Genes and Pathways Involved in CD8+ T Cell Exhaustion versus Memory
- (2012) Travis A. Doering et al. IMMUNITY
- Loss of SLC45A3 protein (prostein) expression in prostate cancer is associated withSLC45A3-ERGgene rearrangement and an unfavorable clinical course
- (2012) Sven Perner et al. INTERNATIONAL JOURNAL OF CANCER
- A description of large-scale metabolomics studies: increasing value by combining metabolomics with genome-wide SNP genotyping and transcriptional profiling
- (2012) Georg Homuth et al. JOURNAL OF ENDOCRINOLOGY
- Bayesian Independent Component Analysis Recovers Pathway Signatures from Blood Metabolomics Data
- (2012) Jan Krumsiek et al. JOURNAL OF PROTEOME RESEARCH
- Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies
- (2012) E. H. Bresnick et al. NUCLEIC ACIDS RESEARCH
- Identifying Neighborhoods of Coordinated Gene Expression and Metabolite Profiles
- (2012) Timothy Hancock et al. PLoS One
- Analyzing Illumina Gene Expression Microarray Data from Different Tissues: Methodological Aspects of Data Analysis in the MetaXpress Consortium
- (2012) Claudia Schurmann et al. PLoS One
- Kruppel-like factor 9 is a circadian transcription factor in human epidermis that controls proliferation of keratinocytes
- (2012) F. Sporl et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bioactive lipid mediators in skin inflammation and immunity
- (2012) Alexandra C. Kendall et al. PROGRESS IN LIPID RESEARCH
- Stitching together Multiple Data Dimensions Reveals Interacting Metabolomic and Transcriptomic Networks That Modulate Cell Regulation
- (2012) Jun Zhu et al. PLOS BIOLOGY
- Mining the Unknown: A Systems Approach to Metabolite Identification Combining Genetic and Metabolic Information
- (2012) Jan Krumsiek et al. PLoS Genetics
- Role of S6K1 in regulation of SREBP1c expression in the liver
- (2011) Shuying Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Critical assessment of human metabolic pathway databases: a stepping stone for future integration
- (2011) Miranda D Stobbe et al. BMC Systems Biology
- Gaussian graphical modeling reconstructs pathway reactions from high-throughput metabolomics data
- (2011) Jan Krumsiek et al. BMC Systems Biology
- Biomarkers for the Prediction of Type 2 Diabetes and Cardiovascular Disease
- (2011) C Herder et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- T-cell activation triggers death receptor-6 expression in a NF-κB and NF-AT dependent manner
- (2011) Martin Klíma et al. MOLECULAR IMMUNOLOGY
- Human metabolic individuality in biomedical and pharmaceutical research
- (2011) Karsten Suhre et al. NATURE
- Metabolite profiles and the risk of developing diabetes
- (2011) Thomas J Wang et al. NATURE MEDICINE
- Lipid parameters for measuring risk of cardiovascular disease
- (2011) Benoit J. Arsenault et al. Nature Reviews Cardiology
- The Human Serum Metabolome
- (2011) Nikolaos Psychogios et al. PLoS One
- Peripheral CLOCK Regulates Target-Tissue Glucocorticoid Receptor Transcriptional Activity in a Circadian Fashion in Man
- (2011) Evangelia Charmandari et al. PLoS One
- Metabolome in schizophrenia and other psychotic disorders: a general population-based study
- (2011) Matej Orešič et al. Genome Medicine
- Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers
- (2011) Kirstin Mittelstrass et al. PLoS Genetics
- Krüppel-like factor KLF9 regulates PPARγ transactivation at the middle stage of adipogenesis
- (2010) H Pei et al. CELL DEATH AND DIFFERENTIATION
- Notch Signaling in the Immune System
- (2010) Freddy Radtke et al. IMMUNITY
- Metabonomic, transcriptomic, and genomic variation of a population cohort
- (2010) Michael Inouye et al. Molecular Systems Biology
- A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers
- (2010) Celine Lefebvre et al. Molecular Systems Biology
- TFM-Explorer: mining cis-regulatory regions in genomes
- (2010) L. Tonon et al. NUCLEIC ACIDS RESEARCH
- Metabolic Pathway Relationships Revealed by an Integrative Analysis of the Transcriptional and Metabolic Temperature Stress-Response Dynamics in Yeast
- (2010) Dirk Walther et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- An Immune Response Network Associated with Blood Lipid Levels
- (2010) Michael Inouye et al. PLoS Genetics
- Role of HDL, ABCA1, and ABCG1 Transporters in Cholesterol Efflux and Immune Responses
- (2009) Laurent Yvan-Charvet et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- A HaemAtlas: characterizing gene expression in differentiated human blood cells
- (2009) Nicholas A. Watkins et al. BLOOD
- Weighted gene co-expression network analysis of the peripheral blood from Amyotrophic Lateral Sclerosis patients
- (2009) Christiaan GJ Saris et al. BMC GENOMICS
- A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance
- (2009) Christopher B. Newgard et al. Cell Metabolism
- Incidence of Type 2 diabetes in the elderly German population and the effect of clinical and lifestyle risk factors: KORA S4/F4 cohort study
- (2009) W. Rathmann et al. DIABETIC MEDICINE
- Glucocorticoids Stimulate Hepatic and Renal Catecholamine Inactivation by Direct Rapid Induction of the Dopamine Sulfotransferase Sult1d1
- (2009) Stephen Wong et al. ENDOCRINOLOGY
- Coexpression network based on natural variation in human gene expression reveals gene interactions and functions
- (2009) R. R. Nayak et al. GENOME RESEARCH
- lumi: a pipeline for processing Illumina microarray
- (2008) P. Du et al. BIOINFORMATICS
- DUSP1 Is Controlled by p53 during the Cellular Response to Oxidative Stress
- (2008) Y.-X. Liu et al. MOLECULAR CANCER RESEARCH
- Genetic Networks of Liver Metabolism Revealed by Integration of Metabolic and Transcriptional Profiling
- (2008) Christine T. Ferrara et al. PLoS Genetics
- Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology
- (2007) Debbie A. Lawlor et al. STATISTICS IN MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search