Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies

Germ-line GATA2 p.THR354MET mutation in familial myelodysplastic syndrome with acquired monosomy 7 and ASXL1 mutation demonstrating rapid onset and poor survival

(2012) C. Bodor et al.   HAEMATOLOGICA

Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature

(2011) J. Kazenwadel et al.   BLOOD

Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency

(2011) R. E. Dickinson et al.   BLOOD

GATA2 finds its macrophage niche

(2011) A. R. Migliaccio et al.   BLOOD

Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome

(2011) A. P. Hsu et al.   BLOOD

Regulation of nucleosome landscape and transcription factor targeting at tissue-specific enhancers by BRG1

(2011) G. Hu et al.   GENOME RESEARCH

Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration

(2011) W. Wu et al.   GENOME RESEARCH

Myelodysplasia in autosomal dominant and sporadic monocytopenia immunodeficiency syndrome: diagnostic features and clinical implications

(2011) K. R. Calvo et al.   HAEMATOLOGICA

Dendritic cell, monocyte, B and NK lymphoid deficiency defines the lost lineages of a new GATA-2 dependent myelodysplastic syndrome

(2011) V. Bigley et al.   HAEMATOLOGICA

Relocalizing Genetic Loci into Specific Subnuclear Neighborhoods

(2011) Hsiang-Ying Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency

(2011) Venetia Bigley et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)

(2011) Pia Ostergaard et al.   NATURE GENETICS

Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia

(2011) Christopher N Hahn et al.   NATURE GENETICS

Genome-Wide Analysis of Transcriptional Reprogramming in Mouse Models of Acute Myeloid Leukaemia

(2011) Nicolas Bonadies et al.   PLoS One

Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes

(2011) J. M. Lamonica et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic framework for GATA factor function in vascular biology

(2011) A. K. Linnemann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emberger syndrome-Primary lymphedema with myelodysplasia: Report of seven new cases

(2010) Sahar Mansour et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Combinatorial Transcriptional Control In Blood Stem/Progenitor Cells: Genome-wide Analysis of Ten Major Transcriptional Regulators

(2010) Nicola K. Wilson et al.   Cell Stem Cell

The Transcription Factor PU.1 Controls Dendritic Cell Development and Flt3 Cytokine Receptor Expression in a Dose-Dependent Manner

(2010) Sebastian Carotta et al.   IMMUNITY

Sumoylation Regulates Interaction of FOG1 with C-terminal-binding Protein (CTBP)

(2010) Jonathan W. Snow et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GATA Switches as Developmental Drivers

(2010) Emery H. Bresnick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis

(2010) Luyang Yu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development

(2010) Sergei Doulatov et al.   NATURE IMMUNOLOGY

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

(2010) Jaclyn R. Gareau et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Building multifunctionality into a complex containing master regulators of hematopoiesis

(2010) T. Fujiwara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia

(2009) D. C. Vinh et al.   BLOOD

FOG-1-mediated recruitment of NuRD is required for cell lineage re-enforcement during haematopoiesis

(2009) Zhiguang Gao et al.   EMBO JOURNAL

NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development

(2009) Annarita Miccio et al.   EMBO JOURNAL

Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression

(2009) Y. Cheng et al.   GENOME RESEARCH

Critical Role for GATA3 in Mediating Tie2 Expression and Function in Large Vessel Endothelial Cells

(2009) Haihua Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GATA-2 L359 V mutation is exclusively associated with CML progression but not other hematological malignancies and GATA-2 P250A is a novel single nucleotide polymorphism

(2009) Su-Jiang Zhang et al.   LEUKEMIA RESEARCH

Controlling Hematopoiesis through Sumoylation-Dependent Regulation of a GATA Factor

(2009) Hsiang-Ying Lee et al.   MOLECULAR CELL

Discovering Hematopoietic Mechanisms through Genome-wide Analysis of GATA Factor Chromatin Occupancy

(2009) Tohru Fujiwara et al.   MOLECULAR CELL

Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis

(2009) Ming Yu et al.   MOLECULAR CELL

BRG1 directly regulates nucleosome structure and chromatin looping of the α globin locus to activate transcription

(2009) Shin-Il Kim et al.   NUCLEIC ACIDS RESEARCH

BRG1 requirement for long-range interaction of a locus control region with a downstream promoter

(2009) S.-I. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical significance of Gata-1, Gata-2, EKLF, and c-MPL expression in acute myeloid leukemia

(2008) Rosa M. Ayala et al.   AMERICAN JOURNAL OF HEMATOLOGY

GATA-2 regulates granulocyte-macrophage progenitor cell function

(2008) N. P. Rodrigues et al.   BLOOD

Acetylation of non-histone proteins modulates cellular signalling at multiple levels

(2008) Stephanie Spange et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Context-dependent Function of Regulatory Elements and a Switch in Chromatin Occupancy between GATA3 and GATA2 RegulateGata2Transcription during Trophoblast Differentiation

(2008) Soma Ray et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SUMOylation and De-SUMOylation: Wrestling with Life's Processes

(2008) Edward T. H. Yeh   JOURNAL OF BIOLOGICAL CHEMISTRY

Antagonism of FOG-1 and GATA factors in fate choice for the mast cell lineage

(2008) Alan B. Cantor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Deletion of Mtg16, a Target of t(16;21), Alters Hematopoietic Progenitor Cell Proliferation and Lineage Allocation

(2008) B. J. Chyla et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular Hallmarks of Endogenous Chromatin Complexes Containing Master Regulators of Hematopoiesis

(2008) R. J. Wozniak et al.   MOLECULAR AND CELLULAR BIOLOGY

Exchange of GATA Factors Mediates Transitions in Looped Chromatin Organization at a Developmentally Regulated Gene Locus

(2008) Huie Jing et al.   MOLECULAR CELL

Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia

(2008) S.-J. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential GATA Factor Stabilities:  Implications for Chromatin Occupancy by Structurally Similar Transcription Factors†

(2007) Louis J. Lurie et al.   BIOCHEMISTRY