Genome metabolome integrated network analysis to uncover connections between genetic variants and complex traits: an application to obesity

Model-specific tests on variance heterogeneity for detection of potentially interacting genetic loci

(2012) Ludwig A Hothorn et al.   BMC GENETICS

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

(2012) Johannes Kettunen et al.   NATURE GENETICS

Novel Loci for Metabolic Networks and Multi-Tissue Expression Studies Reveal Genes for Atherosclerosis

(2012) Michael Inouye et al.   PLoS Genetics

New insights into the mechanism of low high-density lipoprotein cholesterol in obesity

(2011) Hao Wang et al.   Lipids in Health and Disease

A Differential Network Approach to Exploring Differences between Biological States: An Application to Prediabetes

(2011) Beatriz Valcárcel et al.   PLoS One

Association of Genetic Loci with Blood Lipids in the Chinese Population

(2011) Zhou Zhang et al.   PLoS One

Genome-wide association studies and systems biology: together at last

(2011) Mika Ala-Korpela et al.   TRENDS IN GENETICS

Variance heterogeneity analysis for detection of potentially interacting genetic loci: method and its limitations

(2010) Maksim V Struchalin et al.   BMC GENETICS

Leptin Regulates AMPA Receptor Trafficking via PTEN Inhibition

(2010) P. R. Moult et al.   JOURNAL OF NEUROSCIENCE

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

On the Use of Variance per Genotype as a Tool to Identify Quantitative Trait Interaction Effects: A Report from the Women's Genome Health Study

(2010) Guillaume Paré et al.   PLoS Genetics

High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism

(2009) Pasi Soininen et al.   ANALYST

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution

(2009) Cecilia M. Lindgren et al.   PLoS Genetics

Effect of obesity on the plasma lipoprotein subclass profile in normoglycemic and normolipidemic men and women

(2008) F Magkos et al.   INTERNATIONAL JOURNAL OF OBESITY

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

(2008) Chiara Sabatti et al.   NATURE GENETICS

Common variants near MC4R are associated with fat mass, weight and risk of obesity

(2008) Ruth J F Loos et al.   NATURE GENETICS

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

(2008) Gudmar Thorleifsson et al.   NATURE GENETICS

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

(2008) Cristen J Willer et al.   NATURE GENETICS

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

(2008) Yurii S Aulchenko et al.   NATURE GENETICS