Article
Food Science & Technology
Hechun Liu, Feng Wang, Hui Xia, Da Pan, Ligang Yang, Shaokang Wang, Feng Zhao, Guiju Sun
Summary: This study aimed to determine the effects of different sources of m-3 PUFAs on glucolipid metabolism and lipoprotein subfractions in T2DM patients with dyslipidemia. The results showed that plant-derived m-3 PUFAs were more effective at controlling blood glucose levels, while animal-derived m-3 PUFAs were more effective at lowering triglyceride levels. Moreover, intake of animal-derived m-3 PUFAs led to higher levels of large HDL-C subfractions and lower levels of small HDL-C subfractions compared to plant-derived m-3 PUFAs. Both animal and plant-derived m-3 PUFAs have practical value in improving glucose and lipids metabolism in T2DM patients with dyslipidemia.
FOOD SCIENCE AND HUMAN WELLNESS
(2023)
Article
Nutrition & Dietetics
Bojung Seo, Keming Yang, Ka Kahe, Abrar A. Qureshi, Andrew T. Chan, Immaculata De Vivo, Eunyoung Cho, Edward L. Giovannucci, Hongmei Nan
Summary: This study suggests that higher intakes of DHA and consumption of canned tuna are associated with longer leukocyte telomere length (LTL) in US males.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Review
Pharmacology & Pharmacy
Arden R. Barry, Dave L. Dixon
Summary: Omega-3 fatty acids, specifically DHA and EPA, have been debated for their effects on cardiovascular health, with low doses showing limited impact. Icosapent ethyl has shown the most compelling evidence for cardiovascular benefits among various forms of omega-3 fatty acids.
Review
Nutrition & Dietetics
Andrew Elagizi, Carl J. Lavie, Evan O'Keefe, Keri Marshall, James H. O'Keefe, Richard V. Milani
Summary: Interest in the potential cardiovascular benefits of omega-3 polyunsaturated fatty acids (omega-3) began in the 1940s, but there has been controversy due to conflicting results among studies and meta-analyses. Recent large, randomized trials showed discordant findings, with one using a higher dose of omega-3 showing a significant reduction in cardiovascular events. The conflicting results in clinical trials may be due to inadequate dosing of omega-3 and aggressive treatment with other effective therapies.
Review
Cardiac & Cardiovascular Systems
Yujiro Yokoyama, Toshiki Kuno, Sae X. Morita, Leandro Slipczuk, Hisato Takagi, Alexandros Briasoulis, Azeem Latib, Sripal Bangalore, Sean P. Heffron
Summary: The impact of omega-3 fatty acid supplementation on cardiovascular events depends on different types of placebo oils, with EPA showing a greater reduction in risk of revascularization compared to other oils; the combination of EPA+DHA is associated with a reduced risk of cardiovascular death.
JOURNAL OF CARDIOLOGY
(2022)
Review
Nutrition & Dietetics
Meghan Dempsey, Michelle S. Rockwell, Laurel M. Wentz
Summary: The majority of the population lack adequate omega-3 fatty acids (n-3 FA), leading to global deficiencies and poor omega-3 status. This study aimed to evaluate the effect of n-3 FA interventions on omega3-index (O3i) and estimate sufficient intake to meet recommendations.
FRONTIERS IN NUTRITION
(2023)
Review
Environmental Sciences
Priyanshi Sikka, Tapan Behl, Sanchay Sharma, Aayush Sehgal, Saurabh Bhatia, Ahmed Al-Harrasi, Sukhbir Singh, Neelam Sharma, Lotfi Aleya
Summary: Ω-3 fatty acids are recognized for their benefits on physical and mental health, primarily obtained from fish and fish products. Adequate intake of Ω-3 fatty acids can improve brain function and neuronal function, reduce depressive symptoms, and have fewer side effects compared to antidepressants.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Cardiac & Cardiovascular Systems
Richard L. Weinberg, Robert D. Brook, Melvyn Rubenfire, Kim A. Eagle
Summary: Omega-3 polyunsaturated fatty acids play a key role in heart-healthy diet, and can be obtained through fatty fish consumption or fish oil supplementation. They not only treat hypertriglyceridemia, but also prevent cardiovascular events, with additional benefits such as reducing inflammation and improving plaque stability.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Review
Nutrition & Dietetics
Magdalena Ogluszka, Pawel Lipinski, Rafal R. Starzynski
Summary: Telomeres play a key role in protecting chromosome ends and maintaining genome stability, but they shorten with aging. Short telomeres are associated with age-related diseases, but the variability in telomere shortening suggests it is modifiable. Studies have explored the impact of omega-3 fatty acids on telomere shortening, with most indicating a beneficial effect on telomere length.
Article
Nutrition & Dietetics
Estefania Aparicio, Carla Martin-Grau, Cristina Bedmar, Nuria Serrat Orus, Josep Basora, Victoria Arija
Summary: This study found that factors such as high education levels, older age, consumption of fish and seafood, and non-smoking are significantly associated with serum fatty acid concentrations in pregnant women, leading to a better omega-3 fatty acid profile. Further research is needed to explore the health consequences of these findings.
Article
Agriculture, Dairy & Animal Science
A. Irawan, N. Ningsih, Hafizuddin, R. K. Rusli, W. P. S. Suprayogi, N. Akhirini, R. F. Hadi, W. Setyono, A. Jayanegara
Summary: This meta-analysis evaluated the effects of dietary supplementation with n-3 polyunsaturated fatty acids (PUFA) sources on the formation of n-3 PUFA contents in eggs, and identified predictors for DHA formation. The study confirmed that ALA, n-3 PUFA, and the ratio of LA/ALA can be used as predictors for the formation of n-3 fatty acids in eggs. Fish oil showed the highest prediction model for DHA formation.
Article
Food Science & Technology
Chiara Magoni, Stefano Bertacchi, Chiara Maria Giustra, Lorenzo Guzzetti, Radiana Cozza, Michele Ferrari, Anna Torelli, Matteo Marieschi, Danilo Porro, Paola Branduardi, Massimo Labra
Summary: This paper reviews the sustainability and supply chain of omega-3 fatty acids production from microalgae. It highlights the importance of microalgal bioprospecting, engineering approaches, and environmental influence in achieving sustainable production. Additionally, the strategy to promote consumer acceptance of algae-based products is crucial for substituting current sources of omega-3 fatty acids.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2022)
Article
Food Science & Technology
Saranporn Wongpattananukul, Uarna Nungarlee, Arnakorn Ruangprach, Suwaibah Sulong, Promluck Sanporkha, Sirichai Adisakwattana, Sathaporn Ngamukote
Summary: The use of Sacha inchi oil (IPO) as a substitute for animal fat in meat products can improve the nutritional properties by reducing saturated fat content and omega-6/omega-3 ratio while increasing omega-3 fatty acid content. Moreover, it can enhance the emulsion stability and texture properties of sausages. However, the addition of higher amounts of IPO may increase TBARS value during refrigerated storage.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Daniel K. Chen, Adam H. Metherel, Kimia Rezaei, Camilla Parzanini, Chuck T. Chen, Christopher E. Ramsden, Mark Horowitz, Keturah R. Faurot, Beth Macintosh, Daisy Zamora, Richard P. Bazinet
Summary: This study used natural variations in the 13C:12C ratio of food to analyze the metabolism of LNA and EPA to DHA. The results showed that after LNA intake, plasma LNA concentrations remained unchanged while the 613C signature of LNA in the H6 group increased over time. In contrast, the H3H6 and H3 groups demonstrated an increase in plasma EPA and DHA concentrations after EPA intake. Additionally, compound-specific isotope analysis can be used to track the metabolism of dietary fatty acids in humans.
JOURNAL OF LIPID RESEARCH
(2023)
Article
Food Science & Technology
Phakkharawat Sittiprapaporn, Akkarach Bumrungpert, Prayoon Suyajai, Con Stough
Summary: This study conducted a clinical trial on 120 healthy Thai children aged 6-12 years old to investigate the effects of fish oil supplementation on cognition. The results showed that fish oil intake can lead to improved attention and cognitive processing ability in children.
Editorial Material
Cardiac & Cardiovascular Systems
Jose E. Exaire, Timothy A. Mixon
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Giuseppe Di Gioia, Federica Coletti, Lorenzo Buzzelli, Viviana Maestrini, Sara Monosilio, Andrea Segreti, Maria Rosaria Squeo, Erika Lemme, Antonio Nenna, Antonio Pelliccia
Summary: Dyslipidemia is common in Paralympic athletes, with lipid levels influenced by the type of disability and sporting discipline.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Esra Donmez, Sevgi Ozcan, Irfan Sahin, Murat Ziyrek, Ertugrul Okuyan
Summary: This study aimed to evaluate the predictive value of the GRACE risk score in acute pulmonary embolism (PE) patients for 30-day mortality and the need for thrombolytic treatment. The study found that the GRACE risk score, along with the PESI score, were independent risk factors associated with 30-day mortality and the need for thrombolytic treatment. The GRACE risk score showed high sensitivity and specificity in predicting mortality, and its combination with the PESI score helped define high-risk PE patients and predict poor prognosis.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Tom Kai Ming Wang, Reza Reyaldeen, Kevser Akyuz, Zoran B. Popovic, A. Marc Gillinov, Bo Xu, Brian P. Griffin, Milind Y. Desai
Summary: Transthoracic echocardiography (TTE) is commonly used to evaluate isolated tricuspid regurgitation (TR), but there is limited research comparing its quantification with magnetic resonance imaging (MRI). In this study, a novel TTE algorithm was developed to identify severe TR based on TTE parameters. The algorithm had a higher accuracy than the current guidelines' criteria in detecting severe TR by MRI.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Editorial Material
Cardiac & Cardiovascular Systems
Enkhtsogt Sainbayar, Ramzi Ibrahim, Hoang Nhat Pham, Wisam Beauti, Mahek Shahid, Natalie Hickerson, Mohammed Salih, Joao Paulo Ferreira, Mamas A. Mamas
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Richard E. Casazza, Hymie Chera, Carlos Adolfo Rodriguez, Sergey Ayzenberg
Summary: This article presents a case of a patient with known situs inversus who underwent cardiac catheterization and was found to have chronic total occlusion in the right coronary artery. Situs inversus is a rare congenital abnormality characterized by the inverted position of chest and abdominal organs. Cardiac catheterization is uncommon in patients with this particular abnormality, highlighting the importance of customizing techniques to engage coronary arteries and optimize guide support for percutaneous coronary intervention if needed.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Editorial Material
Cardiac & Cardiovascular Systems
Georgiana Pintea Bentea, Brahim Berdaoui, Sophie Samyn, Marielle Morissens, Philippe van de Borne, Jose Castro Rodriguez
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Bulbul Ahmed, Melissa G. Farb, Shakun Karki, Sophia D'Alessandro, Niloo M. Edwards, Noyan Gokce
Summary: This study evaluated the angiogenic capacity of adipose tissue in patients undergoing cardiac surgeries and found that patients with coronary artery disease (CAD) had reduced angiogenic capacity in their pericardial adipose tissue. Gene expression analysis revealed upregulated expression of the anti-angiogenic gene TSP-1 in CAD patients, with no significant differences in other angiogenic factors. Additionally, inhibiting TSP-1 expression significantly improved angiogenic deficiency in CAD patients.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Moshe Rav-Acha, Orli Wube, Oholi Tovia Brodie, Yoav Michowitz, Michael Ilan, Tal Ovdat, Robert Klempfner, Mahmud Suleiman, Ilan Goldenberg, Michael Glikson
Summary: The current guidelines recommend prophylactic implantable cardioverter-defibrillator (ICD) for patients with symptomatic heart failure (HF) and low left ventricular ejection fraction. However, not all patients will benefit from ICD treatment. This study evaluated the feasibility of using the MADIT-II-based Risk Stratification Score (MRSS) to predict the survival benefit of prophylactic ICDs in patients with HF. The results showed that different risk subgroups had varying levels of ICD survival benefit.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ariel Banai, Rachel Retsky, Lior Lupu, Erez Levi, David Zahler, Omri Feder, Roei Merin, Yan Topilsky, Raphael Rosso, Shmuel Banai, Sami Viskin, Ehud Chorin
Summary: This study aims to evaluate the association between electromechanical window (EMW) and ventricular tachyarrhythmias in patients with Takotsubo syndrome (TTS). The study found that TTS patients had a lower EMW value, which was associated with an increased risk of ventricular tachyarrhythmias.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Harun Kundi, Kobina Hagan, Tamer Yahya, Garima Sharma, Sadeer Al-Kindi, Zulqarnain Javed, Khurram Nasir
Summary: Using latent class analysis (LCA), the study identified clinical, demographic, and social subphenotypes in ASCVD population and assessed the risk of all-cause and cardiovascular mortality across different socioclinical classes. The results showed that the younger, female, non-Hispanic Black or Hispanic individuals with a high burden of co-morbidities and unfavorable social determinants of health had the highest risk of mortality in the identified latent classes.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Moises A. Vasquez, Mina Iskander, Mohammed Mustafa, Juan A. Quintero-Martinez, Antonio Luna, Joel Mintz, Jose Noy, Juan Uribe, Ivan Mijares, Eduardo de Marchena, Yiannis S. Chatzizisis
Summary: The benefits of pericardiocentesis (PC) in patients with pulmonary hypertension (PH) and pericardial effusions are unclear. The study found that PC in PH patients is associated with higher in-hospital mortality and rates of cardiovascular complications.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ken Kuwajima, Mana Ogawa, Irving Ruiz, Hiroko Hasegawa, Nobuichiro Yagi, Florian Rader, Robert J. Siegel, Takahiro Shiota
Summary: After cardiac surgery, the longitudinal function of the right ventricle and left ventricle is reduced, despite preserved global functions. In particular, tricuspid annular plane systolic excursion (TAPSE) remains decreased after surgery.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Min -Jung Kim, Robert H. Aseltine Jr, Sara R. Tabtabai
Summary: This study evaluated the rates and causes of 30-day readmissions after discharge for heart failure (HF) as a primary and secondary diagnosis. The findings indicate that efforts to reduce readmission rates should include patients with secondary HF diagnosis, and surveillance should extend to 2 weeks postdischarge to identify at-risk patients.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ya He, Jianzhong Zhou
Summary: This study aimed to examine the relation between reverse septal curvature (RSC) and nonsustained ventricular tachycardia (NSVT) in patients with hypertrophic cardiomyopathy (HCM). The study found that patients with RSC were younger and had a higher incidence of NSVT, and RSC was identified as a strong independent risk factor for NSVT.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)