Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNF in glioblastoma
出版年份 2014 全文链接
标题
Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNF in glioblastoma
作者
关键词
-
出版物
Science Signaling
Volume 7, Issue 338, Pages ra75-ra75
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2014-08-13
DOI
10.1126/scisignal.2005196
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- PKC signaling in glioblastoma
- (2013) Anália do Carmo et al. CANCER BIOLOGY & THERAPY
- EGFR Phosphorylates Tumor-Derived EGFRvIII Driving STAT3/5 and Progression in Glioblastoma
- (2013) Qi-Wen Fan et al. CANCER CELL
- Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma
- (2013) Krishna P.L. Bhat et al. CANCER CELL
- Macrophage biology in development, homeostasis and disease
- (2013) Thomas A. Wynn et al. NATURE
- CSF-1R inhibition alters macrophage polarization and blocks glioma progression
- (2013) Stephanie M Pyonteck et al. NATURE MEDICINE
- Competing molecular interactions of aPKC isoforms regulate neuronal polarity
- (2013) S. S. Parker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neutralizing Tumor-Promoting Chronic Inflammation: A Magic Bullet?
- (2013) L. M. Coussens et al. SCIENCE
- Unknown
- (2012) Salvatore Coniglio et al. MOLECULAR MEDICINE
- Differential macrophage programming in the tumor microenvironment
- (2012) Brian Ruffell et al. TRENDS IN IMMUNOLOGY
- Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage
- (2011) S. I. Grivennikov et al. ANNALS OF THE RHEUMATIC DISEASES
- Immune microenvironments in solid tumors: new targets for therapy
- (2011) S. L. Shiao et al. GENES & DEVELOPMENT
- The brain tumor microenvironment
- (2011) Nikki A. Charles et al. GLIA
- FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR
- (2011) Trever G. Bivona et al. NATURE
- Inflammation meets cancer, with NF-κB as the matchmaker
- (2011) Yinon Ben-Neriah et al. NATURE IMMUNOLOGY
- Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression
- (2011) Mina J Bissell et al. NATURE MEDICINE
- Acquired MET expression confers resistance to EGFR inhibition in a mouse model of glioblastoma multiforme
- (2011) H J Jun et al. ONCOGENE
- Cancer-related inflammation: Common themes and therapeutic opportunities
- (2011) Frances R. Balkwill et al. SEMINARS IN CANCER BIOLOGY
- Understanding Glioblastoma Tumor Biology: The Potential to Improve Current Diagnosis and Treatments
- (2011) Santosh Kesari SEMINARS IN ONCOLOGY
- Recurrent Glioblastoma: A Fresh Look at Current Therapies and Emerging Novel Approaches
- (2011) Mark R. Gilbert SEMINARS IN ONCOLOGY
- Macrophages, innate immunity and cancer: balance, tolerance, and diversity
- (2010) Alberto Mantovani et al. CURRENT OPINION IN IMMUNOLOGY
- NF-κB and STAT3 signaling in glioma: targets for future therapies
- (2010) George P Atkinson et al. Expert Review of Neurotherapeutics
- Inflammation and Colon Cancer
- (2010) Janoš Terzić et al. GASTROENTEROLOGY
- Microglia/macrophages promote glioma progression
- (2010) Haiyan Zhai et al. GLIA
- NFKBIADeletion in Glioblastomas
- (2010) Markus Bredel et al. NEW ENGLAND JOURNAL OF MEDICINE
- NF-κB addiction and its role in cancer: ‘one size does not fit all’
- (2010) M M Chaturvedi et al. ONCOGENE
- Oncogenic Activation of NF- B
- (2010) L. M. Staudt Cold Spring Harbor Perspectives in Biology
- Of the atypical PKCs, Par-4 and p62: recent understandings of the biology and pathology of a PB1-dominated complex
- (2009) J Moscat et al. CELL DEATH AND DIFFERENTIATION
- Inflammation and oncogenesis: a vicious connection
- (2009) Sergei I Grivennikov et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice
- (2009) Leying Zhang et al. GLIA
- Atypical protein kinase C activity is required for extracellular matrix degradation and invasion by Src-transformed cells
- (2009) Elena M. Rodriguez et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Flow cytometry and in vitro analysis of human glioma–associated macrophages
- (2009) Ian F. Parney et al. JOURNAL OF NEUROSURGERY
- Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion
- (2009) D. S. Markovic et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NF- B as a Critical Link Between Inflammation and Cancer
- (2009) M. Karin Cold Spring Harbor Perspectives in Biology
- 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: Design and synthesis of a potent and isoform selective PKC-ζ inhibitor
- (2008) John I. Trujillo et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- NF-κB and cancer—identifying targets and mechanisms
- (2008) Willscott E Naugler et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
- Cancer-related inflammation
- (2008) Alberto Mantovani et al. NATURE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More