Anti-diabetic vanadyl complexes reduced Alzheimer’s disease pathology independent of amyloid plaque deposition

Neuroprotective effects of a triple GLP-1/GIP/glucagon receptor agonist in the APP/PS1 transgenic mouse model of Alzheimer's disease

(2018) Jingjing Tai et al.   BRAIN RESEARCH

Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells

(2018) Sascha Rahn et al.   CANCER LETTERS

Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders

(2018) Katrin Augustin et al.   LANCET NEUROLOGY

Cinnamon, a promising prospect towards Alzheimer’s disease

(2018) Saeideh Momtaz et al.   PHARMACOLOGICAL RESEARCH

PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease

(2017) Wei-Chun J. Hsu et al.   EXPERIMENTAL NEUROLOGY

Synthesis of a new insulin-mimetic anti-diabetic drug containing vitamin A and vanadium(IV) salt: Chemico-biological characterizations

(2017) Abdel Majid A Adam et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Comorbidity Analysis between Alzheimer’s Disease and Type 2 Diabetes Mellitus (T2DM) Based on Shared Pathways and the Role of T2DM Drugs

(2017) Reagon Karki et al.   JOURNAL OF ALZHEIMERS DISEASE

Soluble Oligomers Require a Ganglioside to Trigger Neuronal Calcium Overload

(2017) Roberta Cascella et al.   JOURNAL OF ALZHEIMERS DISEASE

Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease

(2017) Eric Tönnies et al.   JOURNAL OF ALZHEIMERS DISEASE

Multiple Mechanisms Linking Type 2 Diabetes and Alzheimer’s Disease: Testosterone as a Modifier

(2017) Prita R. Asih et al.   JOURNAL OF ALZHEIMERS DISEASE

Speciation of potential anti-diabetic vanadium complexes in real serum samples

(2017) Daniele Sanna et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Discovery of an Orally Bioavailable Benzofuran Analogue That Serves as a β-Amyloid Aggregation Inhibitor for the Potential Treatment of Alzheimer’s Disease

(2017) Hee-Jin Ha et al.   JOURNAL OF MEDICINAL CHEMISTRY

Designer cells tackle diabetes

(2017) Paulina Strzyz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RIPK1 promotes inflammation and β-amyloid accumulation in Alzheimer’s disease

(2017) David C. Rubinsztein   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Presenilin 2 deficiency facilitates Aβ-induced neuroinflammation and injury by upregulating P2X7 expression

(2017) Juliang Qin et al.   Science China-Life Sciences

Soluble pre-fibrillar tau and β-amyloid species emerge in early human Alzheimer’s disease and track disease progression and cognitive decline

(2016) David J. Koss et al.   ACTA NEUROPATHOLOGICA

Attack on amyloid-β protein

(2016) Eric M. Reiman   NATURE

Neurodegenerative disorders: Neural synchronization in Alzheimer's disease

(2016) Liviu Aron et al.   NATURE

Lost memories found

(2016) Prerana Shrestha et al.   NATURE

Memory retrieval by activating engram cells in mouse models of early Alzheimer’s disease

(2016) Dheeraj S. Roy et al.   NATURE

Hope for anti-amyloid antibodies surges, yet again

(2016) Chris Morrison   NATURE BIOTECHNOLOGY

Alzheimer’s disease and gut microbiota

(2016) Xu Hu et al.   Science China-Life Sciences

Protective Effect of Notoginsenoside R1 on an APP/PS1 Mouse Model of Alzheimer's Disease by Up-Regulating Insulin Degrading Enzyme and Inhibiting Aβ Accumulation

(2015) Zhi Li et al.   CNS & Neurological Disorders-Drug Targets

The Molecular Mechanisms and Rational Design of Anti-Diabetic Vanadium Compounds

(2015) Xia Niu et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Cross talk between PI3K-AKT-GSK-3β and PP2A pathways determines tau hyperphosphorylation

(2015) Yixuan Wang et al.   NEUROBIOLOGY OF AGING

Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer's disease

(2015) Marilia S. Albuquerque et al.   Frontiers in Aging Neuroscience

Inflammation, Defective Insulin Signaling, and Mitochondrial Dysfunction as Common Molecular Denominators Connecting Type 2 Diabetes to Alzheimer Disease

(2014) F. G. De Felice et al.   DIABETES

In vivo mapping of hippocampal subfields in mesial temporal lobe epilepsy: Relation to histopathology

(2014) Jan-Christoph Schoene-Bake et al.   HUMAN BRAIN MAPPING

Mortalin/GRP75 Binds to Complement C9 and Plays a Role in Resistance to Complement-dependent Cytotoxicity

(2014) Moran Saar Ray et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of human amylin fibril formation by insulin-mimetic vanadium complexes

(2014) Lei He et al.   Metallomics

Mitochondrial membrane permeabilisation by amyloid aggregates and protection by polyphenols

(2013) Angelique Camilleri et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Vanadyl acetylacetonate upregulates PPARγ and adiponectin expression in differentiated rat adipocytes

(2013) Yaling Wu et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Alzheimer’s disease and insulin resistance: translating basic science into clinical applications

(2013) Fernanda G. De Felice   JOURNAL OF CLINICAL INVESTIGATION

Synthesis, characterization and cell viability test of six vanadyl complexes with acetylacetonate derivatives

(2013) Speranza Sgarbossa et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Vanadium compounds modulate PPARγ activity primarily by increasing PPARγ protein levels in mouse insulinoma NIT-1 cells

(2013) Pan Zhao et al.   Metallomics

Resveratrol Protects DAergic PC12 Cells from High Glucose-Induced Oxidative Stress and Apoptosis: Effect on p53 and GRP75 Localization

(2013) Justine Renaud et al.   NEUROTOXICITY RESEARCH

Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: Implications for diagnostic and therapeutic strategies

(2013) Zhichun Chen et al.   PROGRESS IN NEUROBIOLOGY

Exenatide promotes cognitive enhancement and positive brain metabolic changes in PS1-KI mice but has no effects in 3xTg-AD animals

(2013) M Bomba et al.   Cell Death & Disease

Are oxidative stress and mitochondrial dysfunction the key players in the neurodegenerative diseases?

(2012) Marta Di Carlo et al.   FREE RADICAL RESEARCH

Presymptomatic Alterations in Energy Metabolism and Oxidative Stress in the APP23 Mouse Model of Alzheimer Disease

(2012) Daniela Hartl et al.   JOURNAL OF PROTEOME RESEARCH

Vanadyl bisacetylacetonate protects β cells from palmitate-induced cell death through the unfolded protein response pathway

(2011) Zhonglan Gao et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress

(2011) M. Bauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vanadium in the detection, prevention and treatment of cancer: The in vivo evidence

(2010) Anupam Bishayee et al.   CANCER LETTERS

Insulin resistance, type 2 diabetes, and AD: Cerebrovascular disease or neurodegeneration?

(2010) J. A. Luchsinger   NEUROLOGY

Insulin resistance and amyloidogenesis as common molecular foundation for type 2 diabetes and Alzheimer's disease

(2008) Wei-Qin Zhao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE