Overexpression of MMP13 in human osteoarthritic cartilage is associated with the SMAD-independent TGF-β signalling pathway

TGF-β signal transduction pathways and osteoarthritis

(2015) Guangju Zhai et al.   RHEUMATOLOGY INTERNATIONAL

The global burden of hip and knee osteoarthritis: estimates from the Global Burden of Disease 2010 study

(2014) Marita Cross et al.   ANNALS OF THE RHEUMATIC DISEASES

Association Between Single Nucleotide Polymorphisms of Asporin (ASPN) and BMP5 with the Risk of Knee Osteoarthritis in a Chinese Han Population

(2014) Wenqing Liang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

SMAD3 Is Associated with the Total Burden of Radiographic Osteoarthritis: The Chingford Study

(2014) Erfan Aref-Eshghi et al.   PLoS One

Classification of osteoarthritis phenotypes by metabolomics analysis

(2014) Weidong Zhang et al.   BMJ Open

Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis

(2013) Gehua Zhen et al.   NATURE MEDICINE

Chondrocyte-intrinsic Smad3 represses Runx2-inducible matrix metalloproteinase 13 expression to maintain articular cartilage and prevent osteoarthritis

(2012) Carol G. Chen et al.   ARTHRITIS AND RHEUMATISM

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis

(2011) Ingrid M B H van de Laar et al.   NATURE GENETICS

GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women

(2010) F. M. K. Williams et al.   ARTHRITIS AND RHEUMATISM

Evidence of association between GDF5 polymorphisms and congenital dislocation of the hip in a Caucasian population

(2010) K. Rouault et al.   OSTEOARTHRITIS AND CARTILAGE

Matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin motifs in non-neoplastic diseases

(2010) Takayuki Shiomi et al.   PATHOLOGY INTERNATIONAL

TGF  family signaling: novel insights in development and disease

(2009) K. Wharton et al.   DEVELOPMENT

Increase in ALK1/ALK5 Ratio as a Cause for Elevated MMP-13 Expression in Osteoarthritis in Humans and Mice

(2009) E. N. Blaney Davidson et al.   JOURNAL OF IMMUNOLOGY

Differential upregulation of the three transforming growth factor beta isoforms in human osteoarthritic cartilage

(2008) M Pombo-Suarez et al.   ANNALS OF THE RHEUMATIC DISEASES

A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility

(2008) K. Chapman et al.   HUMAN MOLECULAR GENETICS

Attempt to replicate published genetic associations in a large, well-defined osteoarthritis case–control population (the GOAL study)

(2008) K.L. Limer et al.   OSTEOARTHRITIS AND CARTILAGE