DNA damage response in cisplatin-induced nephrotoxicity

Platinum-induced kidney damage: Unraveling the DNA damage response (DDR) of renal tubular epithelial and glomerular endothelial cells following platinum injury

(2015) Katharina Krüger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

DNA damage response in renal ischemia–reperfusion and ATP-depletion injury of renal tubular cells

(2014) Zhengwei Ma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Nucleotide excision repair: Why is it not used to predict response to platinum-based chemotherapy?

(2014) Nikola A. Bowden   CANCER LETTERS

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

DNA Damage to a Single Chromosome End Delays Anaphase Onset

(2014) Bárbara Alcaraz Silva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparative thermal and thermodynamic study of DNA chemically modified with antitumor drug cisplatin and its inactive analog transplatin

(2014) Dmitri Y. Lando et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Tubular p53 Regulates Multiple Genes to Mediate AKI

(2014) D. Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Frequencies of mutagenic translesion DNA synthesis over cisplatin-guanine intra-strand crosslinks in lacZ plasmids propagated in human cells

(2014) Yoshihiro Fujikawa et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

CHK2 kinase in the DNA damage response and beyond

(2014) L. Zannini et al.   Journal of Molecular Cell Biology

Chemotherapy induced DNA damage response

(2013) Derek Woods et al.   CANCER BIOLOGY & THERAPY

Mechanisms, function and clinical applications of DNp73

(2013) Cuixia Di et al.   CELL CYCLE

Nek1 interacts with Ku80 to assist chromatin loading of replication factors and S-phase progression

(2013) Mallikarjun Patil et al.   CELL CYCLE

Genetic disruption of Abl nuclear import reduces renal apoptosis in a mouse model of cisplatin-induced nephrotoxicity

(2013) P Sridevi et al.   CELL DEATH AND DIFFERENTIATION

Checkpoint kinase 1 in DNA damage response and cell cycle regulation

(2013) Mallikarjun Patil et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nek8 Couples Renal Ciliopathies to DNA Damage and Checkpoint Control

(2013) Peter K. Jackson   MOLECULAR CELL

NEK8 Links the ATR-Regulated Replication Stress Response and S Phase CDK Activity to Renal Ciliopathies

(2013) Hyo Jei Claudia Choi et al.   MOLECULAR CELL

Hesperidin attenuates cisplatin-induced acute renal injury by decreasing oxidative stress, inflammation and DNA damage

(2013) Bidya Dhar Sahu et al.   PHYTOMEDICINE

Autophagy in Acute Kidney Injury

(2013) Man J. Livingston et al.   SEMINARS IN NEPHROLOGY

Repression of ATR pathway by miR-185 enhances radiation-induced apoptosis and proliferation inhibition

(2013) J Wang et al.   Cell Death & Disease

Cisplatin upregulates MSH2 expression by reducing miR-21 to inhibit A549 cell growth

(2012) Yan-Xia Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis

(2012) Wynand P. Roos et al.   CANCER LETTERS

Sibling rivalry in checkpoint control of cell cycle and DNA damage response

(2012) Navjotsingh Pabla et al.   CELL CYCLE

Detection of Early Abl Kinase Activation after Ionizing Radiation by Using a Peptide Biosensor

(2012) Jiabin Tang et al.   CHEMBIOCHEM

The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA

(2011) Michael G. Kemp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

hMSH2 Recruits ATR to DNA Damage Sites for Activation during DNA Damage-induced Apoptosis

(2011) Navjotsingh Pabla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer

(2011) Navjotsingh Pabla et al.   JOURNAL OF CLINICAL INVESTIGATION

Tip60-mediated acetylation activates transcription independent apoptotic activity of Abl

(2011) Zhihua Jiang et al.   Molecular Cancer

Checkpoint kinase 1 (Chk1)-short is a splice variant and endogenous inhibitor of Chk1 that regulates cell cycle and DNA damage checkpoints

(2011) N. Pabla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA Damage Recognition via Activated ATM and p53 Pathway in Nonproliferating Human Prostate Tissue

(2010) S. Jaamaa et al.   CANCER RESEARCH

Aven blocks DNA damage-induced apoptosis by stabilising Bcl-xL

(2010) Ozgur Kutuk et al.   EUROPEAN JOURNAL OF CANCER

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Luteolin ameliorates cisplatin-induced acute kidney injury in mice by regulation of p53-dependent renal tubular apoptosis

(2010) Kyung Pyo Kang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

c-Abl phosphorylation of ΔNp63α is critical for cell viability

(2010) M Yuan et al.   Cell Death & Disease

Mechanisms of Cisplatin Nephrotoxicity

(2010) Ronald P. Miller et al.   Toxins

Common mechanisms of PIKK regulation

(2009) Courtney A. Lovejoy et al.   DNA REPAIR

Mismatch Repair Protein Deficiency Compromises Cisplatin-induced Apoptotic Signaling

(2009) Ryan P. Topping et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The cell cycle and acute kidney injury

(2009) Peter M. Price et al.   KIDNEY INTERNATIONAL

Inhibition of the c-Abl–TAp63 pathway protects mouse oocytes from chemotherapy-induced death

(2009) Stefania Gonfloni et al.   NATURE MEDICINE

ATR and Chk1 Suppress a Caspase-3–Dependent Apoptotic Response Following DNA Replication Stress

(2009) Katie Myers et al.   PLoS Genetics

Photoaffinity Isolation and Identification of Proteins in Cancer Cell Extracts that Bind to Platinum-Modified DNA

(2008) Evan R. Guggenheim et al.   CHEMBIOCHEM

Aven-Dependent Activation of ATM Following DNA Damage

(2008) Jessie Yanxiang Guo et al.   CURRENT BIOLOGY

Regulation and Pathological Role of p53 in Cisplatin Nephrotoxicity

(2008) M. Jiang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Histone H2AX Phosphorylation Independent of ATM after X-irradiation in Mouse Liver and Kidney in situ

(2008) Manabu KOIKE et al.   JOURNAL OF RADIATION RESEARCH

Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells

(2008) Sudharsan Periyasamy-Thandavan et al.   KIDNEY INTERNATIONAL

Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies

(2008) N. Pabla et al.   KIDNEY INTERNATIONAL

Involvement of p53-transactivated Puma in cisplatin-induced renal tubular cell death

(2008) Kazuhiko Tsuruya et al.   LIFE SCIENCES

Yap1 Phosphorylation by c-Abl Is a Critical Step in Selective Activation of Proapoptotic Genes in Response to DNA Damage

(2008) Dan Levy et al.   MOLECULAR CELL

Nuclear trafficking of pro-apoptotic kinases in response to DNA damage

(2008) Kiyotsugu Yoshida   TRENDS IN MOLECULAR MEDICINE