Targeting brain serotonin synthesis: insights into neurodevelopmental disorders with long-term outcomes related to negative emotionality, aggression and antisocial behaviour

Away game or home match: The influence of venue and serotonin transporter genotype on the display of offensive aggression

(2011) Friederike Jansen et al.   BEHAVIOURAL BRAIN RESEARCH

A Genetically Defined Morphologically and Functionally Unique Subset of 5-HT Neurons in the Mouse Raphe Nuclei

(2011) V. Kiyasova et al.   JOURNAL OF NEUROSCIENCE

Altered GABA transmission in a mouse model of increased trait anxiety

(2011) R.O. Tasan et al.   NEUROSCIENCE

The winner and loser effect, serotonin transporter genotype, and the display of offensive aggression

(2011) Vanessa Kloke et al.   PHYSIOLOGY & BEHAVIOR

Adult Raphe-Specific Deletion of Lmx1b Leads to Central Serotonin Deficiency

(2011) Ning-Ning Song et al.   PLoS One

Differential Effects of Prenatal Stress in 5-Htt Deficient Mice: Towards Molecular Mechanisms of Gene × Environment Interactions

(2011) Daniel Van den Hove et al.   PLoS One

Influence of TPH2 variants on diagnosis and response to treatment in patients with major depression, bipolar disorder and schizophrenia

(2011) Alessandro Serretti et al.   PSYCHIATRY RESEARCH

Tryptophan hydroxylase-2 (TPH2) in disorders of cognitive control and emotion regulation: A perspective

(2011) Jonas Waider et al.   PSYCHONEUROENDOCRINOLOGY

Placing prediction into the fear circuit

(2011) Gavan P. McNally et al.   TRENDS IN NEUROSCIENCES

Effects of single and simultaneous lesions of serotonergic and noradrenergic pathways on open-space and bright-space anxiety-like behavior in two animal models

(2010) Nóra Sziray et al.   BEHAVIOURAL BRAIN RESEARCH

Looking on the Bright Side of Serotonin Transporter Gene Variation

(2010) Judith R. Homberg et al.   BIOLOGICAL PSYCHIATRY

Increased vulnerability to psychosocial stress in heterozygous serotonin transporter knockout mice

(2010) A. Bartolomucci et al.   Disease Models & Mechanisms

Widespread hypothalamic-pituitary-adrenocortical axis-relevant and mood-relevant effects of chronic fluoxetine treatment on glucocorticoid receptor gene expression in mice

(2010) Willem Heydendael et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

TPH25′- and 3′-regulatory polymorphisms are differentially associated with HPA axis function and self-injurious behavior in rhesus monkeys

(2010) G.-L. Chen et al.   GENES BRAIN AND BEHAVIOR

GABAergic Interneurons in the Mouse Lateral Amygdala: A Classification Study

(2010) Ludmila Sosulina et al.   JOURNAL OF NEUROPHYSIOLOGY

Serotonin Modulates Fast-Spiking Interneuron and Synchronous Activity in the Rat Prefrontal Cortex through 5-HT1A and 5-HT2A Receptors

(2010) M. V. Puig et al.   JOURNAL OF NEUROSCIENCE

Brain-specific conditional and time-specific inducible Tph2 knockout mice possess normal serotonergic gene expression in the absence of serotonin during adult life

(2010) Claudia Kriegebaum et al.   NEUROCHEMISTRY INTERNATIONAL

Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?

(2010) Michael S. Fanselow et al.   NEURON

Interneurons in the basolateral amygdala

(2010) Jay Spampanato et al.   NEUROPHARMACOLOGY

Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6 and BALB/c congenic mice

(2010) William B. Siesser et al.   NEUROSCIENCE LETTERS

Plastic Synaptic Networks of the Amygdala for the Acquisition, Expression, and Extinction of Conditioned Fear

(2010) Hans-Christian Pape et al.   PHYSIOLOGICAL REVIEWS

Alternative Splicing and Extensive RNA Editing of Human TPH2 Transcripts

(2010) Maik Grohmann et al.   PLoS One

Multiple anxiogenic drugs recruit a parvalbumin-containing subpopulation of GABAergic interneurons in the basolateral amygdala

(2010) Matthew W. Hale et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Modulation of behavioural profile and stress response by 5-HTT genotype and social experience in adulthood

(2009) Friederike Jansen et al.   BEHAVIOURAL BRAIN RESEARCH

A Serotonin-Dependent Mechanism Explains the Leptin Regulation of Bone Mass, Appetite, and Energy Expenditure

(2009) Vijay K. Yadav et al.   CELL

GABAergic interneurons targeting dendrites of pyramidal cells in the CA1 area of the hippocampus

(2009) Thomas Klausberger   EUROPEAN JOURNAL OF NEUROSCIENCE

Selective activation of dorsal raphe nucleus-projecting neurons in the ventral medial prefrontal cortex by controllable stress

(2009) Michael V. Baratta et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: Convergent data from Tph2 knockout mice

(2009) Lise Gutknecht et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The effect of rearing experience and TPH2 genotype on HPA axis function and aggression in rhesus monkeys: A retrospective analysis

(2009) Guo-Lin Chen et al.   HORMONES AND BEHAVIOR

Functional properties of missense variants of human tryptophan hydroxylase 2

(2009) Jeffrey A. McKinney et al.   HUMAN MUTATION

Neurotransmitters and prefrontal cortex–limbic system interactions: implications for plasticity and psychiatric disorders

(2009) Alberto Del Arco et al.   JOURNAL OF NEURAL TRANSMISSION

Predictable chronic mild stress improves mood, hippocampal neurogenesis and memory

(2009) V K Parihar et al.   MOLECULAR PSYCHIATRY

Amygdala Inhibitory Circuits and the Control of Fear Memory

(2009) Ingrid Ehrlich et al.   NEURON

Probing Compulsive and Impulsive Behaviors, from Animal Models to Endophenotypes: A Narrative Review

(2009) Naomi A Fineberg et al.   NEUROPSYCHOPHARMACOLOGY

Mouse plasmacytoma-expressed transcript 1 knock out induced 5-HT disruption results in a lack of cognitive deficits and an anxiety phenotype complicated by hypoactivity and defensiveness

(2009) T.L. Schaefer et al.   NEUROSCIENCE

Growth retardation and altered autonomic control in mice lacking brain serotonin

(2009) N. Alenina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective participation of the bed nucleus of the stria terminalis and CRF in sustained anxiety-like versus phasic fear-like responses

(2009) D.L. Walker et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Fast Synaptic Subcortical Control of Hippocampal Circuits

(2009) V. Varga et al.   SCIENCE

Living in a dangerous world: the shaping of behavioral profile by early environment and 5-HTT genotype

(2009) Rebecca S. Heiming   Frontiers in Behavioral Neuroscience

The vicious cycle towards violence: focus on the negative feedback mechanisms of brain serotonin neurotransmission

(2009) Sietse de Boer   Frontiers in Behavioral Neuroscience

Fear Conditioning and Long-term Potentiation in the Amygdala

(2008) P. Sah et al.   Annals of the New York Academy of Sciences

The role of prior stressor controllability and the dorsal raphé nucleus in sucrose preference and social exploration

(2008) John P. Christianson et al.   BEHAVIOURAL BRAIN RESEARCH

Additive effects of serotonin transporter and tryptophan hydroxylase-2 gene variation on neural correlates of affective processing

(2008) Turhan Canli et al.   BIOLOGICAL PSYCHOLOGY

Differential effects of imipramine and phenelzine on corticosteroid receptor gene expression in mouse brain: Potential relevance to antidepressant response

(2008) Willem Heydendael et al.   BRAIN RESEARCH

Stress Upregulates TPH1 but not TPH2 mRNA in the Rat Dorsal Raphe Nucleus: Identification of Two TPH2 mRNA Splice Variants

(2008) Nashat Abumaria et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Dorsal hippocampus involvement in delay fear conditioning depends upon the strength of the tone‐footshock association

(2008) Jennifer J. Quinn et al.   HIPPOCAMPUS

Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice

(2008) Lise Gutknecht et al.   JOURNAL OF NEURAL TRANSMISSION

Failure to Mount Adaptive Responses to Stress Results in Dysregulation and Cell Death in the Midbrain Raphe

(2008) J. G. McEuen et al.   JOURNAL OF NEUROSCIENCE

C1473G polymorphism in mousetph2gene is linked to tryptophan hydroxylase-2 activity in the brain, intermale aggression, and depressive-like behavior in the forced swim test

(2008) Daria V. Osipova et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Tph2 gene variants modulate response control processes in adult ADHD patients and healthy individuals

(2008) C G Baehne et al.   MOLECULAR PSYCHIATRY

A loss-of-function mutation in tryptophan hydroxylase 2 segregating with attention-deficit/hyperactivity disorder

(2008) J McKinney et al.   MOLECULAR PSYCHIATRY

Elevated expression of tryptophan hydroxylase-2 mRNA at the neuronal level in the dorsal and median raphe nuclei of depressed suicides

(2008) H Bach-Mizrachi et al.   MOLECULAR PSYCHIATRY

Excess of serotonin affects embryonic interneuron migration through activation of the serotonin receptor 6

(2008) O Riccio et al.   MOLECULAR PSYCHIATRY

Amygdala intercalated neurons are required for expression of fear extinction

(2008) Ekaterina Likhtik et al.   NATURE

Targeting the murine serotonin transporter: insights into human neurobiology

(2008) Dennis L. Murphy et al.   NATURE REVIEWS NEUROSCIENCE

Activation of the ventral medial prefrontal cortex during an uncontrollable stressor reproduces both the immediate and long-term protective effects of behavioral control

(2008) J. Amat et al.   NEUROSCIENCE

Genetic Disruption of Both Tryptophan Hydroxylase Genes Dramatically Reduces Serotonin and Affects Behavior in Models Sensitive to Antidepressants

(2008) Katerina V. Savelieva et al.   PLoS One

Enhanced contextual fear memory in central serotonin-deficient mice

(2008) J.-X. Dai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of GSK3  in behavioral abnormalities induced by serotonin deficiency

(2008) J.-M. Beaulieu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identifying Molecular Substrates in a Mouse Model of the Serotonin Transporter × Environment Risk Factor for Anxiety and Depression

(2007) Valeria Carola et al.   BIOLOGICAL PSYCHIATRY

The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioural differences between mouse strains

(2007) Katja Tenner et al.   NEUROSCIENCE LETTERS