Article
Agronomy
Nikolaos Katsenios, Panagiotis Sparangis, Sofia Chanioti, Marianna Giannoglou, Dimitris Leonidakis, Miltiadis V. Christopoulos, George Katsaros, Aspasia Efthimiadou
Summary: The study found that specific environments have a significant impact on maize yield, protein, and fiber content, and using appropriate genotypes under certain conditions can improve both yield and quality characteristics.
Article
Fisheries
Yihua Chen, Yukuan Chen, Liang Tao, Xinxin Du, Zhiguo Dong, Donghong Niu, Jiale Li
Summary: This study investigates genotype by environment interactions of growth traits in razor clams reared in outdoor ponds and semi-natural environments. The results show significant genetic differences among families in different aquaculture environments. The heritabilities for growth traits are low to moderate, indicating that these traits can be effectively selected in both environments. This study provides guidance for breeding programs of razor clams in different aquaculture environments.
AQUACULTURE REPORTS
(2022)
Article
Energy & Fuels
Jingchao Sun, Hongming Na, Tianyi Yan, Zichang Che, Ziyang Qiu, Yuxing Yuan, Yingnan Li, Tao Du, Yanli Song, Xin Fang
Summary: The comprehensive assessment of production systems is crucial for sustainable production practices in the manufacturing industry. Existing assessment methods lack comprehensiveness, especially in terms of material, energy, environment, and economics. This paper proposes a new assessment method called Comprehensive Value Flow Analysis, which effectively describes and classifies activities in the network of material, energy, environment, and economics. A case study of an iron and steel enterprise demonstrates the effectiveness of the method in identifying issues and providing valuable suggestions for sustainable development.
Article
Plant Sciences
Natasa Ljubicic, Vera Popovic, Vladimir Ciric, Marko Kostic, Bojana Ivosevic, Dragana Popovic, Milos Pandzic, Seddiq El Musafah, Snezana Jankovic
Summary: This study examined the responses of ten winter wheat cultivars to stressful conditions of halomorphic soil, solonetz type, finding that wheat genotypes responded differently to stress conditions and ameliorative measures.
Article
Environmental Studies
Tadhg O'Mahony
Summary: Cost-benefit analysis is crucial for evaluating the welfare gains or losses of investments and should consider environmental impacts. The choice of time horizon can have a significant impact on results, potentially more than discount rates. For projects with long-term environmental effects, timescales of 100+ years are recommended for economic evaluation to avoid bias towards more carbon-intensive or environmentally damaging projects.
ENVIRONMENTAL IMPACT ASSESSMENT REVIEW
(2021)
Article
Plant Sciences
Vasileios Greveniotis, Elisavet Bouloumpasi, Stylianos Zotis, Athanasios Korkovelos, Dimitrios Kantas, Constantinos G. Ipsilandis
Summary: This study assessed the relationship between multiple locations and genotypes, analyzed the adaptability and stability of faba beans, and proposed the most ideal cultivation conditions and genotypes. The results showed that crude protein content, plant height, and thousand-seed weight were positively correlated with seed yield, while other qualitative variables were negatively correlated. Tanagra cultivar exhibited the highest seed yield under conventional management, and Ste1 and Ste2 showed promising genetic materials. Based on the results, Tanagra cultivar and Ste2 genotype are the most ideal choices.
Article
Agricultural Engineering
B. Todd Campbell, Ramdeo Seepaul, Joseph E. Iboyi, William F. Anderson, Brian S. Baldwin, Rick Bennett, Carl R. Crozier, Sheeja George, Austin K. Hagan, Dewey Lee, Bisoondat Macoon, Daniel Mailhot, Jesse I. Morrison, Michael J. Mulvaney, Angela Post, Ian M. Small, David L. Wright
Summary: Extensive field evaluations were conducted across several locations in the southeastern US to assess the agronomic performance and stability of carinata genotypes. Results showed that carinata can produce viable grain yields in the region, but freezing temperatures pose a challenge to winter production. The southeastern US should be divided into three mega environments for future breeding efforts.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Horticulture
Marcos Claudio S. Virtuoso, Tiago S. Valente, Edgard Henrique Costa Silva, Leila Trevisan Braz, Rita de Cassia Panizzi, Pablo Forlan Vargas
Summary: This study assessed the influence of different screening conditions on resistance classification and the occurrence of environmental effects on melon genotypes with monogenic dominant resistance locus to Didymella bryoniae. The results showed that controlled environment with disc inoculation was more aggressive to all genotypes, while spore inoculation was less harmful and allowed better characterization of resistance level. Regardless of the inoculation method, differences between genotypes were smaller under greenhouse conditions.
SCIENTIA HORTICULTURAE
(2022)
Article
Biology
Roger Marcelo Martinez, Tsai-Tsen Liao, Yang-Teng Fan, Yu-Chun Chen, Chenyi Chen
Summary: Martinez, Liao, and colleagues investigate the interaction between variations in genes linked to serotonergic brain function and the processing of fearful stimuli. They find that certain genetic variations are associated with larger fearful MMN amplitudes in males, indicating an impact on threat processing and social cognition.
COMMUNICATIONS BIOLOGY
(2022)
Article
Agronomy
Xing Huang, Su Jang, Backki Kim, Zhongze Piao, Edilberto Redona, Hee-Jong Koh
Summary: The study showed that both environment and genotype x environment interaction significantly affect rice yield and yield-component traits, with GEI explaining 37.1% of yield variation. Through multiple environment trials of over 80 rice varieties, 19 desirable genotypes were identified with high productivity and broad adaptability to different climates.
Article
Veterinary Sciences
Muhammad Rashid, Naveed Zahra, Amna Chudhary, Tauseef Ur Rehman, Muhammad Tahir Aleem, Abdulaziz Alouffi, Aymen Mohammed, Muhammad Imran Rashid, Muhammad Ehsan, Muhammad Irfan Malik, Ghulam Hussain Dilber, Amir Bakhsh, Mashal M. Almutairi
Summary: Intestinal parasitic infection is a major challenge for animal health and welfare. This study evaluated the efficacy and impact of anthelmintic drugs on buffaloes and cattle, and found that the drugs can significantly reduce the impact of parasites on animal productivity, health, and well-being.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Plant Sciences
Damiano Puglisi, Stefano Delbono, Andrea Visioni, Hakan Ozkan, Ibrahim Kara, Ana M. Casas, Ernesto Igartua, Giampiero Vale, Angela Roberta Lo Piero, Luigi Cattivelli, Alessandro Tondelli, Agostino Fricano
Summary: MAGIC lines have mosaic genomes generated by shuffling genetic material of founder parents, used for investigating genetic bases of traits in cereal crops. Genomic prediction models are usually fitted using unrelated accessions or individuals of biparental families. Empirical analyses showed that limited number of MAGIC lines can predict grain yield with values varying from 0.25 to 0.60, suggesting that the population can be used for training genomic prediction models.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Economics
Utsav Panta, Pranav Gairola, N. Nezamuddin
Summary: Electric buses are being considered as an important part of future urban transportation systems due to concerns regarding environmental pollution, greenhouse gas emissions, and depleting petroleum resources. However, the transition process requires substantial financial resources. To assist decision-making within financial constraints, an optimization framework has been developed. This framework focuses on maximizing the benefit-to-cost ratio by evaluating fuel savings and emissions reduction when transitioning to electric buses. The framework has been tested in Delhi, India and suggests that at least 30% of the electricity should come from clean energy sources to maximize the environmental benefits of bus electrification. This framework is an important tool for public transit agencies in planning the initial phases of bus electrification.
Article
Biochemistry & Molecular Biology
Tariq O. Faquih, N. Ahmad Aziz, Sarah L. Gardiner, Ruifang Li-Gao, Renee de Mutsert, Yuri Milaneschi, Stella Trompet, J. Wouter Jukema, Frits R. Rosendaal, Astrid van Hylckama Vlieg, Ko Willems van Dijk, Dennis O. Mook-Kanamori
Summary: Based on the data from three European cohorts, this study found that non-pathogenic CAG repeat sizes below 36 in the HTT gene are associated with abnormal metabolite levels, which may be mediated through lower BMI.
HUMAN MOLECULAR GENETICS
(2023)
Article
Horticulture
Anna Diveky-Ertsey, Marta Ladanyi, Barbara Biro, Monika Mate, Dora Drexler, Ferenc Toth, Krisztina Bozine Pullai, Attila Gere, Peter Pusztai, Laszlo Csambalik
Summary: This study investigates the impact of open-field vs. protected production on various bioactive compound parameters and antioxidant status of tomato PGRs. The analysis reveals that the phytonutrient content of certain PGRs is influenced more by microclimatic conditions than production location. Additionally, different PGRs perform differently in different production systems. These findings enrich the nutritional datasets of tomato landraces and have important implications for the conservation and utilization of PGRs in breeding programs.
Article
Surgery
Verena Buchecker, Ines Koska, Claudia Pace, Steven R. Talbot, Rupert Palme, Andre Bleich, Heidrun Potschka
Summary: Chronic epilepsy models require neurosurgical procedures including depth electrode implants. The intrahippocampal kainate model is a frequently used chronic paradigm, which is based on chemoconvulsant administration and status epilepticus induction during the surgical procedure. This experimental approach raises the question of the extent to which this approach affects postsurgical recovery.
EUROPEAN SURGICAL RESEARCH
(2023)
Article
Surgery
Annika Bach-Hagemann, Ekaterina Harder, Laura Warner, Catharina Conzen-Dilger, Tobias Philip Schmidt, Sarah Pinkernell, Rupert Palme, Ute Lindauer
Summary: This study aimed to assess the burden inflicted on animals after subarachnoid hemorrhage (SAH) or sham surgery in order to provide a scientific evaluation. Using a multimodal approach, the researchers conducted various behavior tests, clinical scoring, and biochemical marker analysis in male Wistar rats. The results showed an increase in clinical scores and weight loss after surgery, indicating impairment in the animals. However, further research is needed to classify the severity of suffering experienced by the animals.
EUROPEAN SURGICAL RESEARCH
(2023)
Article
Surgery
Renee Michele Girbig, Jasmin Baier, Rupert Palme, Rene Tolba, Anne Rix, Fabian Kiessling
Summary: This study aimed to investigate the possible effects of ultrasound imaging on the welfare of healthy mice and explore the potential influence of ultrasound and molecular ultrasound on the well-being and therapy response in breast cancer-bearing mice. The results showed that repeated ultrasound examinations had no detectable impact on the welfare of healthy and tumor-bearing mice. However, the combination of ultrasound and isoflurane anesthesia may attenuate immunological processes in tumor-bearing animals and affect responses to antitumor therapy.
EUROPEAN SURGICAL RESEARCH
(2023)
Article
Surgery
Anna Maria Kuemmecke, Leonie Zieglowski, Lisa Ernst, Rupert Palme, Rene H. Tolba
Summary: This study investigated sex differences in rats following partial hepatectomy. The results suggest that males and females respond similarly, indicating the importance of examining both sexes in translational research. However, further investigation is needed to explore a broader spectrum of measures.
EUROPEAN SURGICAL RESEARCH
(2023)
Article
Agriculture, Dairy & Animal Science
Anina Vogt, Uta Koenig von Borstel, Susanne Waiblinger, Rupert Palme, Kerstin Barth
Summary: Measurement of fecal cortisol metabolites (FGCM) is a well-established, noninvasive method for assessing stress in adult dairy cattle. However, its validity for unweaned dairy calves has not yet been confirmed, and the milk proportion in the diet may affect the FGCM concentrations. This study aimed to determine if there is a peak in FGCM concentrations in unweaned dairy calves on a milk-based diet when exposed to a stressor, and to compare it with calves on a solid-based diet after weaning. The results showed a clear peak in FGCM concentrations on both diet types, with higher concentrations and longer time lag in unweaned calves.
JOURNAL OF DAIRY SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
M. Wieland, D. Nydam, C. M. Geary, K. L. Case, J. M. Melvin, S. Shirky, C. Santisteban, R. Palme, W. Heuwieser
Summary: This study compared the effects of intermittent milking and thrice daily milking on the well-being, udder health, milk production, and risk of culling of dairy cows during the final week of lactation. The results indicated that cows subjected to intermittent milking experienced less udder engorgement and pain, lower concentrations of fecal glucocorticoid metabolites, lower risk of intramammary infection, higher milk production, lower somatic cell count, and lower culling risk. This research provides valuable insights for improving the health and milk production of dairy cows.
JOURNAL OF DAIRY SCIENCE
(2023)
Article
Zoology
Olivier Kaisin, Felipe Bufalo, Rodrigo Amaral, Rupert Palme, Pascal Poncin, Fany Brotcorne, Laurence Culot
Summary: By using non-invasive methods, the study explored the relationship between glucocorticoid levels and behavior in black lion tamarins. The results showed that fecal glucocorticoid metabolite levels varied according to changes in activity and resting time on a long-term scale, and were influenced by interspecific competition on a short-term scale. These findings provide insights into the physiological stress responses of wild species to environmental and social pressures.
AMERICAN JOURNAL OF PRIMATOLOGY
(2023)
Article
Multidisciplinary Sciences
Daniel Segelcke, Steven R. Talbot, Rupert Palme, Carmen La Porta, Esther Pogatzki-Zahn, Andre Bleich, Anke Tappe-Theodor
Summary: Rodent behavior is influenced by environmental conditions, including housing conditions and familiarization with the experimenter. This study aimed to investigate the effects of different housing conditions and experimenter familiarization on pain-related behavior in male mice with peripheral neuropathy. The results showed that housing conditions and experimenter familiarization had an impact on mechanical sensitivity, gait pattern, anxiety-like behavior, and stress levels in the mice. These findings highlight the importance of considering environmental conditions in preclinical pain studies.
SCIENTIFIC REPORTS
(2023)
Article
Ecology
Luca Corlatti, Rupert Palme, Teresa G. Valencak, Kimberlina Marie Gomez
Summary: Chronic stress in wildlife can have negative effects on individual fitness, including increased likelihood of disease and parasitic infections. This study investigated the relationship between forage quality and stress levels in Alpine chamois, using fecal cortisol metabolites as indicators of stress. The results suggest that higher quality forage is associated with decreased stress hormones during the summer months.
ECOLOGY AND EVOLUTION
(2023)
Article
Behavioral Sciences
Sophia Marie Quante, Viktoria Siewert, Rupert Palme, Sylvia Kaiser, Norbert Sachser, S. Helene Richter
Summary: Touchscreen-based procedures are increasingly used in experimental animal research as a promising approach to translational research and to reduce experimenter effects. However, the training phase required for the animals to adapt to the touchscreen test may cause stress and anxiety-like behavior. This study aimed to investigate the effects of terminating touchscreen training on mice, specifically looking at behavior, hormone levels, and exploratory activity. The results suggest that the termination of touchscreen training did not have a significant impact, contradicting the hypothesis of enrichment loss.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
Marisol Parada Sarmiento, Lydia Lanzoni, Leandro Sabei, Matteo Chincarini, Rupert Palme, Adroaldo Jose Zanella, Giorgio Vignola
Summary: This study demonstrates that lameness in pregnant sows can lead to decreased placental efficiency in inactivating stress hormones, potentially impacting the welfare of the offspring. Therefore, greater attention should be paid to the lameness of sows as it may affect the welfare of both the sow and her offspring.
Article
Multidisciplinary Sciences
Dorota Kidawa, Katarzyna Wojczulanis-Jakubas, Dariusz Jakubas, Rupert Palme, Mateusz Barcikowski
Summary: This study found individual differences in chick calls of little auks and a high acceptance rate of cross-fostered chicks by parents. This suggests the potential usage of vocal recognition in offspring identification by seabirds, although parents may disregard individual characteristics enabling chick discrimination.
SCIENTIFIC REPORTS
(2023)
Article
Ecology
Sascha Roesner, Dana G. Schabo, Rupert Palme, Tomas Lorenc, Emily Mussard-Forster, Roland Brandl, Jöerg Mueller
Summary: By assessing the impact of habitat quality, abiotic factors, and human disturbance on the physiological stress response of capercaillie, it was found that high-quality habitats reduce stress levels, tourism-free refuge areas are important, and individual differences strongly influence response to environmental factors.
Article
Veterinary Sciences
Flavia Santamaria, Rolf Schlagloth, Ludovica Valenza, Rupert Palme, Deidre de Villiers, Joerg Henning
Summary: Habitat loss, urbanisation and climate change can cause stress in koalas. Non-invasive monitoring of faecal cortisol metabolites (FCMs) can be used to evaluate the impact of stress. The effectiveness of two enzyme immunoassays (EIAs), 50c and cortisol, in measuring FCM values in wild, stressed koalas was tested. Diseased and injured koalas had significantly higher FCM values than clinically healthy control animals as measured by the 50c EIA. Only the 50c EIA detected higher absolute values in males, and also found that females showed a more elevated response to stress manifested by injury and disease. The cortisol EIA was also found unreliable in detecting stress in rehabilitated koalas treated with synthetic glucocorticoids as it cross-reacts with these chemicals.
VETERINARY SCIENCES
(2023)
Article
Multidisciplinary Sciences
Laura Becker, Anne S. Mallien, Natascha Pfeiffer, Christiane Brandwein, Steven R. Talbot, Andre Bleich, Rupert Palme, Heidrun Potschka, Peter Gass
Summary: The forced swim test (FST) is a traditional assay used to assess the antidepressant effects of drugs. There has been a debate about the test's potential aversiveness and burden on animals. This study conducted an evidence-based assessment of the test's severity in rats and found that it causes only mild effects, primarily hypothermia. The researchers suggest refining the test by using warmer water temperatures to maintain the animals' physiological body temperature.
Article
Behavioral Sciences
Radwa H. Lutfy, Sherine Abdel Salam, Haitham S. Mohammed, Marwa M. Shakweer, Amina E. Essawy
Summary: Insufficient sleep is associated with impaired hypothalamic activity and declined attentional performance. This study found that near-infrared (NIR) laser therapy can alleviate the effects of sleep deprivation on the hypothalamus, enhance antioxidant status, suppress neuroinflammation, and regulate cellular activity.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Durmus Ali Aslanlar, Emin Fatih Visneci, Mehmet Oz, K. Esra Nurullahoglu Atalik
Summary: Mood disorders caused by chemotherapy have become more important as cancer patients' survival increases. This study used methotrexate to induce mood disorders in rats and found that treatment with the antioxidant N-acetylcysteine (NAC) can alleviate anxiety and depression-like behaviors, increase antioxidant capacity, reduce oxidative stress and inflammatory response, and regulate brain chemistry. The findings suggest that NAC treatment could be an effective strategy in revising the treatment for individuals suffering from chemotherapy-induced mood disorders.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Yunfan Zhang, Yunbin Zhang, Zhuangfei Chen, Ping Ren, Yu Fu
Summary: This study systematically investigated the effects of extremely low intensity HF-rTMS on cognition in mice and found that 40 Hz rTMS significantly impaired exploratory behavior and spatial memory at both 10 mT and 1 mT conditions. Additionally, 40 Hz stimulation had remarkably different effects on exploratory behavior depending on intensity, compared to 10 Hz stimulation.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Xuan Xuan, Guangling Zheng, Wenjia Zhu, Qionghua Sun, Yawei Zeng, Juan Du, Xusheng Huang
Summary: This study examines the functional characteristics of the cerebellum in individuals with sALS and their correlation with clinical data. The results show changes in both local and global functional connectivity in the cerebellum of sALS patients, suggesting a pathophysiological role of the cerebellum in sALS.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Mehdi Rezaei, Mohammad Mahdi Shariat Bagheri
Summary: This study examined the efficacy of tDCS for PTSD and related symptoms, as well as the factors that may predict response to tDCS. The results showed that tDCS had a positive effect in reducing symptoms of PTSD, depression, anxiety, and anhedonia. The severity of symptoms at baseline may also predict the response to tDCS.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Huimin Wu, Yiqun Guo, Yaoyao Zhang, Le Zhao, Cheng Guo
Summary: Aggression can have serious consequences, but little is known about its personality and neurological origins in children. This study investigated the relationship between self-esteem, aggression, and brain structure in healthy children, and found that self-esteem was negatively associated with aggression. The study also revealed that increased cortical thickness in certain brain areas may be a potential mechanism linking low self-esteem to aggression in children.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Xinmei Deng, Kexin Chen, Xiaoming Chen, Lin Zhang, Mingping Lin, Xiaoqing Li, Qiufeng Gao
Summary: Parental involvement affects the relationship and communication between parents and adolescents. This study found that high parental involvement is associated with stronger brain-to-brain synchrony during shared positive emotional experiences, while low parental involvement is associated with stronger synchrony during shared negative emotional experiences.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Xin Deng, I. -Shuo Huang, Kourtlin Williams, Marcy L. Wainwright, Paul Zimba, Riccardo Mozzachiodi
Summary: Food deprivation can lead to neurological dysfunctions, including memory impairment. This study used Aplysia as an animal model to investigate the memory deficits caused by prolonged food deprivation. The results showed that 14 days of food deprivation decreased the level of 5-HT in the hemolymph, which contributed to the lack of sensitization and its cellular correlates. However, exogenous application of 5-HT partially induced sensitization in the food deprived animals.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Ihori Kobayashi, Patrick A. Forcelli
Summary: The study found that intervention with the dual orexin receptor antagonist suvorexant did not have the expected effects on extinction memory and sleep. Higher percentages of REM sleep were associated with poorer extinction memory recall and stronger fear responses. Additionally, the fear extinction training protocol used in this study did not lead to complete fear extinction.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Jiyan Xu, Xinlu Chen, Shuai Liu, Ziqi Wei, Minhui Xu, Linhao Jiang, Xue Han, Liangyu Peng, Xiaoping Gu, Tianjiao Xia
Summary: This study investigated the effects of nicotinamide mononucleotide (NMN) on oxidative stress and cognitive function in postoperative cognitive dysfunction (POCD) mice. The results showed that NMN pretreatment reduced oxidative stress damage and alleviated cognitive impairment in POCD mice.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Song Liu, Qiang Wu, Liyue Wang, Cong Xing, Junrui Guo, Baicao Li, Hongpeng Ma, Hao Zhong, Mi Zhou, Shibo Zhu, Rusen Zhu, Guangzhi Ning
Summary: In this study, a systematic assessment indicator was developed to objectively evaluate hindlimb motor function recovery in rats after thoracic contusion SCI. By screening CatWalk XT gait parameters and using exploratory factor analysis, 38 suitable parameters for assessing motor function were identified. A reliable Coordinated Function Index (CFI) was proposed based on these parameters and simplified for improved assessment efficacy.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Kyosuke Shiga, Shota Miyaguchi, Yasuto Inukai, Naofumi Otsuru, Hideaki Onishi
Summary: This study aimed to investigate the effects of transcranial alternating current stimulation (tACS) on microscale learning in implicit motor tasks. Contrary to expectations, the results showed that the stimulation protocol had no significant effects on microscale learning, revealing a novel aspect of microscale learning in implicit motor tasks.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Cahide Aslan, Rahime Aslankoc, Ozlem Ozmen, Buse Nur Suluk, Oguzhan Kavrik, Nurhan Gumral
Summary: This study examined the negative effects of high fructose corn syrup on prefrontal cortex damage in adolescent rats, as well as the protective role of vitamin D.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Matin Baghani, Arad Bolouri-Roudsari, Reyhaneh Askari, Abbas Haghparast
Summary: The study suggests that the orexinergic system in the dentate gyrus region of the brain may act as an endogenous pain control system and a potential target for treating stress-related disorders.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Sen Zhou, Yang Liu, Binbin Xue, Peigen Yuan
Summary: This study confirmed that low-dose Esketamine alleviates LPS-induced depressive symptoms by regulating the GSK-3 beta/NLRP3 pathway. Appropriate doses of Esketamine are essential for the treatment of depression in the clinical setting.
BEHAVIOURAL BRAIN RESEARCH
(2024)