The ‘headache tree’ via umbellulone and TRPA1 activates the trigeminovascular system

Could an Allosteric Gating Model Explain the Role of TRPA1 in Cold Hypersensitivity?

(2011) M. Salazar et al.   JOURNAL OF NEUROSCIENCE

Trpv1 Reporter Mice Reveal Highly Restricted Brain Distribution and Functional Expression in Arteriolar Smooth Muscle Cells

(2011) D. J. Cavanaugh et al.   JOURNAL OF NEUROSCIENCE

TRPM3 Is a Nociceptor Channel Involved in the Detection of Noxious Heat

(2011) Joris Vriens et al.   NEURON

N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity

(2011) Luciano De Petrocellis et al.   PHARMACOLOGICAL RESEARCH

An NMR Spectroscopic Method to Identify and Classify Thiol-Trapping Agents: Revival of Michael Acceptors for Drug Discovery?

(2010) Cristina Avonto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

TRPA1 receptors mediate environmental irritant-induced meningeal vasodilatation

(2010) Phillip Edward Kunkler et al.   PAIN

Inhibition of capsaicin-induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK-0974)

(2009) Simon R. Sinclair et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Pleasant natural scent with unpleasant effects: Cluster headache-like attacks triggered by Umbellularia californica

(2009) S Benemei et al.   CEPHALALGIA

Migraine and the Environment

(2009) Deborah I. Friedman et al.   HEADACHE

Modulation of the cold-activated cation channel TRPM8 by surface charge screening

(2009) Frank Mahieu et al.   JOURNAL OF PHYSIOLOGY-LONDON

The role of CGRP in the pathophysiology of migraine and efficacy of CGRP receptor antagonists as acute antimigraine drugs

(2009) Carlos M. Villalón et al.   PHARMACOLOGY & THERAPEUTICS

TRPA1 acts as a cold sensor in vitro and in vivo

(2009) Y. Karashima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRANSIENT RECEPTOR POTENTIAL VANILLOID-1–MEDIATED CALCIUM RESPONSES ARE INHIBITED BY THE ALKYLAMINE ANTIHISTAMINES DEXBROMPHENIRAMINE AND CHLORPHENIRAMINE

(2008) Laura R. Sadofsky et al.   EXPERIMENTAL LUNG RESEARCH

Intracellular alkalization causes pain sensation through activation of TRPA1 in mice

(2008) Fumitaka Fujita et al.   JOURNAL OF CLINICAL INVESTIGATION

TRPA1 is a major oxidant sensor in murine airway sensory neurons

(2008) Bret F. Bessac et al.   JOURNAL OF CLINICAL INVESTIGATION

Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial

(2008) Tony W Ho et al.   LANCET

Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1

(2008) S. Materazzi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Radial stretch reveals distinct populations of mechanosensitive mammalian somatosensory neurons

(2008) M. R. C. Bhattacharya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA