Intrathymic Notch3 and CXCR4 combinatorial interplay facilitates T-cell leukemia propagation

Maml1 acts cooperatively with Gli proteins to regulate sonic hedgehog signaling pathway

(2017) Roberta Quaranta et al.   Cell Death & Disease

KISS1R signaling promotes invadopodia formation in human breast cancer cell via β-arrestin2/ERK

(2016) Cameron G. Goertzen et al.   CELLULAR SIGNALLING

Role of CXCR4-mediated bone marrow colonization in CNS infiltration by T cell acute lymphoblastic leukemia

(2016) Tanja Rezzonico Jost et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression

(2016) G Franciosa et al.   ONCOGENE

Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies

(2016) P Bernasconi-Elias et al.   ONCOGENE

CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia

(2015) C. Arieta Kuksin et al.   BLOOD

CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphoblastic Leukemia

(2015) Diana Passaro et al.   CANCER CELL

CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance

(2015) Lauren A. Pitt et al.   CANCER CELL

Multidrug Resistance Protein-4 Influences Aspirin Toxicity in Human Cell Line

(2015) Isabella Massimi et al.   MEDIATORS OF INFLAMMATION

Mouse Sertoli Cells Sustain De Novo Generation of Regulatory T Cells by Triggering the Notch Pathway Through Soluble JAGGED11

(2014) Antonio Francesco Campese et al.   BIOLOGY OF REPRODUCTION

 -Arrestins - new players in Notch and GPCR signaling pathways in mammals

(2014) L. Puca et al.   JOURNAL OF CELL SCIENCE

Kinetics of In Vivo Proliferation and Death of Memory and Naive CD8 T Cells: Parameter Estimation Based on 5-Bromo-2'-Deoxyuridine Incorporation in Spleen, Lymph Nodes, and Bone Marrow

(2014) E. Parretta et al.   JOURNAL OF IMMUNOLOGY

Cell competition is a tumour suppressor mechanism in the thymus

(2014) Vera C. Martins et al.   NATURE

Notch3/Jagged1 Circuitry Reinforces Notch Signaling and Sustains T-ALL

(2014) Maria Pelullo et al.   NEOPLASIA

Opposing chemokine gradients control human thymocyte migration in situ

(2013) Joanna Halkias et al.   JOURNAL OF CLINICAL INVESTIGATION

Ubiquitin-dependent regulation of G protein-coupled receptor trafficking and signaling

(2012) Adriano Marchese et al.   CELLULAR SIGNALLING

The molecular basis of T cell acute lymphoblastic leukemia

(2012) Pieter Van Vlierberghe et al.   JOURNAL OF CLINICAL INVESTIGATION

Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia

(2011) Irene Homminga et al.   CANCER CELL

Notch3 and Canonical NF- B Signaling Pathways Cooperatively Regulate Foxp3 Transcription

(2011) A. Barbarulo et al.   JOURNAL OF IMMUNOLOGY

Notch1 regulates chemotaxis and proliferation by controlling the CC-chemokine receptors 5 and 9 in T cell acute lymphoblastic leukaemia

(2011) Leonardo Mirandola et al.   JOURNAL OF PATHOLOGY

Stromal cell-derived factor 1α and CXCR4: newly defined requirements for efficient thymic β-selection

(2010) Michelle L. Janas et al.   TRENDS IN IMMUNOLOGY

Site-specific metastasis formation

(2010) Adit Ben-Baruch   Cell Adhesion & Migration

Thymic development beyond β-selection requires phosphatidylinositol 3-kinase activation by CXCR4

(2009) Michelle L. Janas et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CXCR4 acts as a costimulator during thymic β-selection

(2009) Paul C Trampont et al.   NATURE IMMUNOLOGY

Differential subcellular localization regulates c-Cbl E3 ligase activity upon Notch3 protein in T-cell leukemia

(2009) S Checquolo et al.   ONCOGENE

CCL3 and CXCL12 regulate trafficking of mouse bone marrow NK cell subsets

(2008) G. Bernardini et al.   BLOOD

NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity

(2008) F. Armstrong et al.   BLOOD

Bone marrow stromal cells and the upregulation of interleukin-8 production in human T-cell acute lymphoblastic leukemia through the CXCL12/CXCR4 axis and the NF- B and JNK/AP-1 pathways

(2008) M. T. Scupoli et al.   HAEMATOLOGICA