Pathogenesis and prevention of rheumatic disease: focus on preclinical RA and SLE

Systematic Review: Accuracy of Anti–Citrullinated Peptide Antibodies for Diagnosing Rheumatoid Arthritis

(2013) Penny F. Whiting   ANNALS OF INTERNAL MEDICINE

Circulating plasmablasts/plasmacells as a source of anticitrullinated protein antibodies in patients with rheumatoid arthritis

(2013) Priscilla F Kerkman et al.   ANNALS OF THE RHEUMATIC DISEASES

The type I IFN signature as a biomarker of preclinical rheumatoid arthritis

(2013) Joyce Lübbers et al.   ANNALS OF THE RHEUMATIC DISEASES

Anti-Citrullinated Protein Antibodies in Unaffected First-Degree Relatives of Rheumatoid Arthritis Patients

(2013) Lillian Barra et al.   ARTHRITIS AND RHEUMATISM

Multiplex Analyses of Antibodies Against Citrullinated Peptides in Individuals Prior to Development of Rheumatoid Arthritis

(2013) Mikael Brink et al.   ARTHRITIS AND RHEUMATISM

Relatives Without Rheumatoid Arthritis Show Reactivity to Anti-Citrullinated Protein/Peptide Antibodies That Are Associated With Arthritis-Related Traits: Studies of the Etiology of Rheumatoid Arthritis

(2013) Kendra A. Young et al.   ARTHRITIS AND RHEUMATISM

Infections in vasculitis

(2013) Loïc Guillevin   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

How do autoimmune diseases cluster in families? A systematic review and meta-analysis

(2013) Jorge Cárdenas-Roldán et al.   BMC Medicine

Elevated Subclinical Double-Stranded DNA Antibodies and Future Proliferative Lupus Nephritis

(2013) S. W. Olson et al.   Clinical Journal of the American Society of Nephrology

Relation between Asymptomatic Proteinase 3 Antibodies and Future Granulomatosis with Polyangiitis

(2013) S. W. Olson et al.   Clinical Journal of the American Society of Nephrology

Genetic susceptibility to SLE: Recent progress from GWAS

(2013) Yong Cui et al.   JOURNAL OF AUTOIMMUNITY

First-degree Relatives of Patients with Rheumatoid Arthritis Exhibit High Prevalence of Joint Symptoms

(2013) I. Smolik et al.   JOURNAL OF RHEUMATOLOGY

Prevalence of Anti-Peptidylarginine Deiminase Type 4 Antibodies in Rheumatoid Arthritis and Unaffected First-degree Relatives in Indigenous North American Populations

(2013) E. D. Ferucci et al.   JOURNAL OF RHEUMATOLOGY

Immunopathogenic mechanisms of systemic autoimmune disease

(2013) Marie Wahren-Herlenius et al.   LANCET

Single-Cell Analysis Reveals Isotype-Specific Autoreactive B Cell Repertoires in Sjögren’s Syndrome

(2013) Cuong Q. Nguyen et al.   PLoS One

The Role of Microparticles in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus

(2013) J. R. Dye et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

(2013) R. Khandpur et al.   Science Translational Medicine

Association of Environmental and Genetic Factors and Gene-Environment Interactions With Risk of Developing Rheumatoid Arthritis

(2013) Elizabeth W. Karlson et al.   ARTHRITIS CARE & RESEARCH

Periodontal disease, Porphyromonas gingivalis, and rheumatoid arthritis: what triggers autoimmunity and clinical disease?

(2013) Jose U Scher et al.   ARTHRITIS RESEARCH & THERAPY

Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

(2013) Jose U Scher et al.   eLife

Greater prevalence of seropositivity for anti-cyclic citrullinated peptide antibody in unaffected first-degree relatives in multicase rheumatoid arthritis-affected families

(2013) Seong-Kyu Kim et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

A prediction rule for the development of arthritis in seropositive arthralgia patients

(2012) Lotte Arwen van de Stadt et al.   ANNALS OF THE RHEUMATIC DISEASES

DNA methylome signature in rheumatoid arthritis

(2012) Kazuhisa Nakano et al.   ANNALS OF THE RHEUMATIC DISEASES

Recent insights into the genetic basis of systemic lupus erythematosus

(2012) Ornella Josephine Rullo et al.   ANNALS OF THE RHEUMATIC DISEASES

EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis

(2012) Danielle M Gerlag et al.   ANNALS OF THE RHEUMATIC DISEASES

Prevalence and sociodemographic correlates of antinuclear antibodies in the United States

(2012) Minoru Satoh et al.   ARTHRITIS AND RHEUMATISM

Familial clustering of the serum cytokine profile in the relatives of rheumatoid arthritis patients

(2012) Hani S. El-Gabalawy et al.   ARTHRITIS AND RHEUMATISM

Porphyromonas gingivalisand disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis

(2012) Ted R. Mikuls et al.   ARTHRITIS AND RHEUMATISM

Multifunctional T cell reactivity with native and glycosylated type II collagen in rheumatoid arthritis

(2012) Omri Snir et al.   ARTHRITIS AND RHEUMATISM

Brief Report: Anti-Carbamylated Protein Antibodies Are Present in Arthralgia Patients and Predict the Development of Rheumatoid Arthritis

(2012) Jing Shi et al.   ARTHRITIS AND RHEUMATISM

Streptococcus and rheumatic fever

(2012) Madeleine W. Cunningham   CURRENT OPINION IN RHEUMATOLOGY

Lupus and Epstein-Barr

(2012) Judith A. James et al.   CURRENT OPINION IN RHEUMATOLOGY

Proteinase-3 Antineutrophil Cytoplasm Antibody Positivity in Patients Without Primary Systemic Vasculitis

(2012) Stephen Paul McAdoo et al.   JCR-JOURNAL OF CLINICAL RHEUMATOLOGY

Palindromic Rheumatism: A Pre-Rheumatoid Arthritis State?

(2012) S. J. KATZ et al.   JOURNAL OF RHEUMATOLOGY

Genetics of spondyloarthritis—beyond the MHC

(2012) John D. Reveille   Nature Reviews Rheumatology

Pre-rheumatoid arthritis: predisposition and transition to clinical synovitis

(2012) William P. Arend et al.   Nature Reviews Rheumatology

Autoantibody Epitope Spreading in the Pre-Clinical Phase Predicts Progression to Rheumatoid Arthritis

(2012) Jeremy Sokolove et al.   PLoS One

Lung disease with anti-CCP antibodies but not rheumatoid arthritis or connective tissue disease

(2012) Aryeh Fischer et al.   RESPIRATORY MEDICINE

Environmental and Gene-Environment Interactions and Risk of Rheumatoid Arthritis

(2012) Elizabeth W. Karlson et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Palindromic Rheumatism

(2012) Rtika R. Abraham   SOUTHERN MEDICAL JOURNAL

Antiphospholipid antibodies: Evaluation of the thrombotic risk

(2012) Katrien M.J. Devreese   THROMBOSIS RESEARCH

Reactive Arthritis: Developments and Challenges in Diagnosis and Treatment

(2012) Davina Morris et al.   Current Rheumatology Reports

Treatment Strategies in Early Rheumatoid Arthritis and Prevention of Rheumatoid Arthritis

(2012) M. Kristen Demoruelle et al.   Current Rheumatology Reports

Antibodies against cyclic citrullinated peptides of IgG, IgA and IgM isotype and rheumatoid factor of IgM and IgA isotype are increased in unaffected members of multicase rheumatoid arthritis families from northern Sweden

(2011) Lisbeth Ärlestig et al.   ANNALS OF THE RHEUMATIC DISEASES

Analysis of autosomal genes reveals gene–sex interactions and higher total genetic risk in men with systemic lupus erythematosus

(2011) Travis Hughes et al.   ANNALS OF THE RHEUMATIC DISEASES

Identification and functional characterization of T cells reactive to citrullinated vimentin in HLA-DRB1*0401-positive humanized mice and rheumatoid arthritis patients

(2011) Omri Snir et al.   ARTHRITIS AND RHEUMATISM

Avidity maturation of anti-citrullinated protein antibodies in rheumatoid arthritis

(2011) P. Suwannalai et al.   ARTHRITIS AND RHEUMATISM

Brief Report: Airways abnormalities and rheumatoid arthritis-related autoantibodies in subjects without arthritis: Early injury or initiating site of autoimmunity?

(2011) M. Kristen Demoruelle et al.   ARTHRITIS AND RHEUMATISM

Systemic lupus erythematosus

(2011) Sean O’Neill et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

The Therapeutic Potential of Epigenetics in Autoimmune Diseases

(2011) Maria De Santis et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Leaky Gut and Autoimmune Diseases

(2011) Alessio Fasano   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Non-HLA genes modulate the risk of rheumatoid arthritis associated with HLA-DRB1 in a susceptible North American Native population

(2011) H S El-Gabalawy et al.   GENES AND IMMUNITY

Unraveling the functional implications of GWAS: how T cell protein tyrosine phosphatase drives autoimmune disease

(2011) Julie Zikherman et al.   JOURNAL OF CLINICAL INVESTIGATION

Asymptomatic Autoantibodies Associate with Future Anti-glomerular Basement Membrane Disease

(2011) S. W. Olson et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Lupus arthritis--do we have a clinically useful classification?

(2011) E. M. A. Ball et al.   RHEUMATOLOGY

Antibodies of IgG, IgA and IgM isotypes against cyclic citrullinated peptide precede the development of rheumatoid arthritis

(2011) Heidi Kokkonen et al.   ARTHRITIS RESEARCH & THERAPY

Autoantibodies predate the onset of systemic lupus erythematosus in northern Sweden

(2011) Catharina Eriksson et al.   ARTHRITIS RESEARCH & THERAPY

Antibodies to Citrullinated Protein Antigens (ACPAs): Clinical and Pathophysiologic Significance

(2011) M. Kristen Demoruelle et al.   Current Rheumatology Reports

Epitope spreading of the anti-citrullinated protein antibody response occurs before disease onset and is associated with the disease course of early arthritis

(2010) D. van der Woude et al.   ANNALS OF THE RHEUMATIC DISEASES

Prevention of autoimmune rheumatic disease: state of the art and future perspectives

(2010) L. Klareskog et al.   ANNALS OF THE RHEUMATIC DISEASES

The extent of the anti-citrullinated protein antibody repertoire is associated with arthritis development in patients with seropositive arthralgia

(2010) L. A. van de Stadt et al.   ANNALS OF THE RHEUMATIC DISEASES

Different stages of rheumatoid arthritis: features of the synovium in the preclinical phase

(2010) M. G. H. van de Sande et al.   ANNALS OF THE RHEUMATIC DISEASES

Autoimmunity to peptidyl arginine deiminase type 4 precedes clinical onset of rheumatoid arthritis

(2010) Jason R. Kolfenbach et al.   ARTHRITIS AND RHEUMATISM

Gene expression profiling in autoantibody-positive patients with arthralgia predicts development of arthritis

(2010) Lisa G. M. van Baarsen et al.   ARTHRITIS AND RHEUMATISM

Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll-like receptor 4 and Fcγ receptor

(2010) Jeremy Sokolove et al.   ARTHRITIS AND RHEUMATISM

Aberrant IgG galactosylation precedes disease onset, correlates with disease activity, and is prevalent in autoantibodies in rheumatoid arthritis

(2010) Altan Ercan et al.   ARTHRITIS AND RHEUMATISM

Alcohol consumption and markers of inflammation in women with preclinical rheumatoid arthritis

(2010) Bing Lu et al.   ARTHRITIS AND RHEUMATISM

The number of elevated cytokines and chemokines in preclinical seropositive rheumatoid arthritis predicts time to diagnosis in an age-dependent manner

(2010) Kevin D. Deane et al.   ARTHRITIS AND RHEUMATISM

Effect of interactions of glutathione S-transferase T1, M1, and P1 and HMOX1 gene promoter polymorphisms with heavy smoking on the risk of rheumatoid arthritis

(2010) Brendan T. Keenan et al.   ARTHRITIS AND RHEUMATISM

Network analysis of associations between serum interferon-α activity, autoantibodies, and clinical features in systemic lupus erythematosus

(2010) Corinna E. Weckerle et al.   ARTHRITIS AND RHEUMATISM

Predicting the risk of coronary heart disease

(2010) T.H.S. Dent   ATHEROSCLEROSIS

In Situ B Cell-Mediated Immune Responses and Tubulointerstitial Inflammation in Human Lupus Nephritis

(2010) A. Chang et al.   JOURNAL OF IMMUNOLOGY

Antibodies to Porphyromonas gingivalis Are Associated with Anticitrullinated Protein Antibodies in Patients with Rheumatoid Arthritis and Their Relatives

(2010) C. A. HITCHON et al.   JOURNAL OF RHEUMATOLOGY

Studies of Filipino patients with systemic lupus erythematosus: Autoantibody profile of first-degree relatives

(2010) SV Navarra et al.   LUPUS

Lack of seroconversion of rheumatoid factor and anti-cyclic citrullinated peptide in patients with early inflammatory arthritis: a systematic literature review

(2010) Lillian Barra et al.   RHEUMATOLOGY

The Lupus Family Registry and Repository

(2010) A. Rasmussen et al.   RHEUMATOLOGY

Type 1 Diabetes TrialNet-An International Collaborative Clinical Trials Network

(2009) Jay S. Skyler et al.   Annals of the New York Academy of Sciences

Effect of dexamethasone on autoantibody levels and arthritis development in patients with arthralgia: a randomised trial

(2009) W. H. Bos et al.   ANNALS OF THE RHEUMATIC DISEASES

Beneficial effects of a 3-week course of intramuscular glucocorticoid injections in patients with very early inflammatory polyarthritis: results of the STIVEA trial

(2009) S. M. M. Verstappen et al.   ANNALS OF THE RHEUMATIC DISEASES

Impact of smoking as a risk factor for developing rheumatoid arthritis: a meta-analysis of observational studies

(2009) D Sugiyama et al.   ANNALS OF THE RHEUMATIC DISEASES

Impact of T-cell costimulation modulation in patients with undifferentiated inflammatory arthritis or very early rheumatoid arthritis: a clinical and imaging study of abatacept (the ADJUST trial)

(2009) P. Emery et al.   ANNALS OF THE RHEUMATIC DISEASES

Arthritis development in patients with arthralgia is strongly associated with anti-citrullinated protein antibody status: a prospective cohort study

(2009) W. H. Bos et al.   ANNALS OF THE RHEUMATIC DISEASES

Gene-environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident rheumatoid arthritis

(2009) E W Karlson et al.   ANNALS OF THE RHEUMATIC DISEASES

Familial associations of rheumatoid arthritis with autoimmune diseases and related conditions

(2009) Kari Hemminki et al.   ARTHRITIS AND RHEUMATISM

A prospective approach to investigating the natural history of preclinical rheumatoid arthritis (RA) using first-degree relatives of probands with RA

(2009) Jason R. Kolfenbach et al.   ARTHRITIS AND RHEUMATISM

Biomarkers of inflammation and development of rheumatoid arthritis in women from two prospective cohort studies

(2009) Elizabeth W. Karlson et al.   ARTHRITIS AND RHEUMATISM

Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients

(2009) Omri Snir et al.   ARTHRITIS AND RHEUMATISM

Pathogenesis of primary adrenal insufficiency

(2009) Eystein Husebye et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Interferon signature gene expression is correlated with autoantibody profiles in patients with incomplete lupus syndromes

(2009) Q.-Z. Li et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Rheumatoid arthritis (RA)-specific autoantibodies in patients with interstitial lung disease and absence of clinically apparent articular RA

(2009) Alison M. Gizinski et al.   CLINICAL RHEUMATOLOGY

Societal cost of rheumatoid arthritis patients in the US

(2009) Howard Birnbaum et al.   CURRENT MEDICAL RESEARCH AND OPINION

Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis

(2009) Natalia Wegner et al.   IMMUNOLOGICAL REVIEWS

Autoantibodies and the Risk of Cardiovascular Events

(2009) K. P. LIANG et al.   JOURNAL OF RHEUMATOLOGY

Comparison of Threshold Cutpoints and Continuous Measures of Anti-Cyclic Citrullinated Peptide Antibodies in Predicting Future Rheumatoid Arthritis

(2009) L. B. CHIBNIK et al.   JOURNAL OF RHEUMATOLOGY

Immunogenetic Risks of Anti-Cyclical Citrullinated Peptide Antibodies in a North American Native Population with Rheumatoid Arthritis and Their First-degree Relatives

(2009) H. S. El-GABALAWY et al.   JOURNAL OF RHEUMATOLOGY

Sex Differences in Autoimmune Disease from a Pathological Perspective

(2008) DeLisa Fairweather et al.   AMERICAN JOURNAL OF PATHOLOGY

Duration of pre-rheumatoid arthritis anti-cyclic citrullinated peptide positivity is positively associated with age at seroconversion

(2008) W H Bos et al.   ANNALS OF THE RHEUMATIC DISEASES

Alcohol consumption is associated with decreased risk of rheumatoid arthritis: results from two Scandinavian case-control studies

(2008) H Kallberg et al.   ANNALS OF THE RHEUMATIC DISEASES

Immunity to Citrullinated Proteins in Rheumatoid Arthritis

(2008) Lars Klareskog et al.   Annual Review of Immunology

Marked differences in fine specificity and isotype usage of the anti-citrullinated protein antibody in health and disease

(2008) Andreea Ioan-Facsinay et al.   ARTHRITIS AND RHEUMATISM

Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice

(2008) Jonathan A. Hill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mechanisms of Disease: autoantigens as clues to the pathogenesis of myositis

(2008) Tomeka L Suber et al.   Nature clinical practice. Rheumatology

Cytokines, autoantibodies and viral antibodies in premorbid and postdiagnostic sera from patients with rheumatoid arthritis: case-control study nested in a cohort of Norwegian blood donors

(2007) K T Jorgensen et al.   ANNALS OF THE RHEUMATIC DISEASES

Duration of preclinical rheumatoid arthritis-related autoantibody positivity increases in subjects with older age at time of disease diagnosis

(2007) D S Majka et al.   ANNALS OF THE RHEUMATIC DISEASES