Genetics of spondyloarthritis—beyond the MHC

Evidence to support IL-13 as a risk locus for psoriatic arthritis but not psoriasis vulgaris

(2011) J. Bowes et al.   ANNALS OF THE RHEUMATIC DISEASES

Confirmation of TNIP1 and IL23A as susceptibility loci for psoriatic arthritis

(2011) J. Bowes et al.   ANNALS OF THE RHEUMATIC DISEASES

High resolution mapping in the major histocompatibility complex region identifies multiple independent novel loci for psoriatic arthritis

(2011) P. Rahman et al.   ANNALS OF THE RHEUMATIC DISEASES

The genetic basis of spondyloarthritis

(2011) J. D. Reveille   ANNALS OF THE RHEUMATIC DISEASES

Progress in the genetics of ankylosing spondylitis

(2011) M. A. Brown   Briefings in Functional Genomics

Improved risk prediction for Crohn's disease with a multi-locus approach

(2011) J. Kang et al.   HUMAN MOLECULAR GENETICS

Expression of MHC class I dimers and ERAP1 in an ankylosing spondylitis patient cohort

(2011) Elaine C. Campbell et al.   IMMUNOLOGY

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

(2011) Patrick Brest et al.   NATURE GENETICS

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

(2011) David M Evans et al.   NATURE GENETICS

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming

(2011) G. Kochan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential major histocompatibility complex class I chain-related A allele associations with skin and joint manifestations of psoriatic disease

(2011) R. Pollock et al.   TISSUE ANTIGENS

A Meta-Analysis of Genome-Wide Association Scans Identifies IL18RAP, PTPN2, TAGAP, and PUS10 As Shared Risk Loci for Crohn's Disease and Celiac Disease

(2011) Eleonora A. M. Festen et al.   PLoS Genetics

Association of STAT3 and TNFRSF1A with ankylosing spondylitis in Han Chinese

(2010) S. I. Davidson et al.   ANNALS OF THE RHEUMATIC DISEASES

Variants in linkage disequilibrium with the late cornified envelope gene cluster deletion are associated with susceptibility to psoriatic arthritis

(2010) J. Bowes et al.   ANNALS OF THE RHEUMATIC DISEASES

Elucidating the chromosome 9 association with AS; CARD9 is a candidate gene

(2010) J J Pointon et al.   GENES AND IMMUNITY

Distinct and overlapping genetic loci in crohnʼs disease and ulcerative colitis: Correlations with pathogenesis

(2010) Matti Waterman et al.   INFLAMMATORY BOWEL DISEASES

Endogenous PGE2 promotes the induction of human Th17 responses by fungal β-glucan

(2010) Maria Cristina Gagliardi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Serum Cytokine Receptors in Ankylosing Spondylitis: Relationship to Inflammatory Markers and Endoplasmic Reticulum Aminopeptidase Polymorphisms

(2010) N. HAROON et al.   JOURNAL OF RHEUMATOLOGY

Genetic Studies of Ankylosing Spondylitis in Koreans Confirm Associations with ERAP1 and 2p15 Reported in White Patients

(2010) S.-Y. BANG et al.   JOURNAL OF RHEUMATOLOGY

Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease

(2010) Yukihide Momozawa et al.   NATURE GENETICS

Association analyses identify six new psoriasis susceptibility loci in the Chinese population

(2010) Liang-Dan Sun et al.   NATURE GENETICS

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

(2010) John D Reveille et al.   NATURE GENETICS

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

(2010) Dermot P B McGovern et al.   NATURE GENETICS

Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

(2010) Eva Ellinghaus et al.   NATURE GENETICS

Genome-wide association analysis identifies three psoriasis susceptibility loci

(2010) Philip E Stuart et al.   NATURE GENETICS

Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis

(2010) Ulrike Hüffmeier et al.   NATURE GENETICS

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1

(2010) Amy Strange et al.   NATURE GENETICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

(2010) Jung-Hyun Park et al.   NATURE IMMUNOLOGY

Evidence for Significant Overlap between Common Risk Variants for Crohn's Disease and Ankylosing Spondylitis

(2010) Debby Laukens et al.   PLoS One

Association of Variants at 1q32 and STAT3 with Ankylosing Spondylitis Suggests Genetic Overlap with Crohn's Disease

(2010) Patrick Danoy et al.   PLoS Genetics

Diverse Genome-wide Association Studies Associate the IL12/IL23 Pathway with Crohn Disease

(2009) Kai Wang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

CARD9 Signaling in the Innate Immune Response

(2009) Jürgen Ruland   Annals of the New York Academy of Sciences

The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene tumour necrosis factor receptor type 1-associated death domain (TRADD)

(2009) J. J. Pointon et al.   ANNALS OF THE RHEUMATIC DISEASES

Deletion of LCE3C and LCE3B genes at PSORS4 does not contribute to susceptibility to psoriatic arthritis in German patients

(2009) U. Huffmeier et al.   ANNALS OF THE RHEUMATIC DISEASES

Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis

(2009) F. W. L. Tsui et al.   ANNALS OF THE RHEUMATIC DISEASES

HLA-B27 misfolding and the unfolded protein response augment interleukin-23 production and are associated with Th17 activation in transgenic rats

(2009) Monica L. DeLay et al.   ARTHRITIS AND RHEUMATISM

Association of a specific ERAP1/ARTS1 haplotype with disease susceptibility in ankylosing spondylitis

(2009) W. P. Maksymowych et al.   ARTHRITIS AND RHEUMATISM

Association ofERAP1, but notIL23R, with ankylosing spondylitis in a Han Chinese population

(2009) Stuart I. Davidson et al.   ARTHRITIS AND RHEUMATISM

The interplay between the geographic distribution of HLA-B27 alleles and their role in infectious and autoimmune diseases: A unifying hypothesis

(2009) Alessandro Mathieu et al.   AUTOIMMUNITY REVIEWS

Genome-wide association scan yields new insights into the immunopathogenesis of psoriasis

(2009) J T Elder   GENES AND IMMUNITY

Interleukin-23 receptor gene variants in Hungarian systemic lupus erythematosus patients

(2009) Eniko Safrany et al.   INFLAMMATION RESEARCH

Association between IL13 Polymorphisms and Psoriatic Arthritis Is Modified by Smoking

(2009) Kristina Callis Duffin et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

IL-23R Polymorphisms in Patients with Ankylosing Spondylitis in Korea

(2009) I.-H. SUNG et al.   JOURNAL OF RHEUMATOLOGY

Association of ARTS1 Gene Polymorphisms with Ankylosing Spondylitis in the Hungarian Population: The rs27044 Variant Is Associated with HLA-B*2705 Subtype in Hungarian Patients with Ankylosing Spondylitis

(2009) B. PAZAR et al.   JOURNAL OF RHEUMATOLOGY

Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: randomised, double-blind, placebo-controlled, crossover trial

(2009) Alice Gottlieb et al.   LANCET

Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21

(2009) Xue-Jun Zhang et al.   NATURE GENETICS

Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis

(2009) Rafael de Cid et al.   NATURE GENETICS

Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways

(2009) Rajan P Nair et al.   NATURE GENETICS

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

(2009) Rachel Cooney et al.   NATURE MEDICINE

Association between the interleukin 23 receptor and ankylosing spondylitis is confirmed by a new UK case-control study and meta-analysis of published series

(2009) T. Karaderi et al.   RHEUMATOLOGY

Multiple Loci within the Major Histocompatibility Complex Confer Risk of Psoriasis

(2009) Bing-Jian Feng et al.   PLoS Genetics

The IL23R Arg381Gln non-synonymous polymorphism confers susceptibility to ankylosing spondylitis

(2008) B Rueda et al.   ANNALS OF THE RHEUMATIC DISEASES

Association of interleukin-23 receptor variants with ankylosing spondylitis

(2008) Proton Rahman et al.   ARTHRITIS AND RHEUMATISM

Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases

(2008) Maria Armaka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Polymorphisms of the IL12B and IL23R Genes Are Associated with Psoriasis

(2008) Rajan P. Nair et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Further Genetic Evidence for Three Psoriasis-Risk Genes: ADAM33, CDKAL1, and PTPN22

(2008) Yonghong Li et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

(2008) Sheila A Fisher et al.   NATURE GENETICS

Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease

(2008) Subra Kugathasan et al.   NATURE GENETICS

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

(2008) Steven A McCarroll et al.   NATURE GENETICS

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

A Genome-Wide Association Study of Psoriasis and Psoriatic Arthritis Identifies New Disease Loci

(2008) Ying Liu et al.   PLoS Genetics