A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus

Adjuvant Therapy for Melanoma

(2012) Diwakar Davar et al.   CANCER JOURNAL

Effect of IL28B Genotype on Early Viral Kinetics During Interferon-Free Treatment of Patients With Chronic Hepatitis C

(2012) Tom W. Chu et al.   GASTROENTEROLOGY

Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma

(2012) Hashem B. El-Serag   GASTROENTEROLOGY

Combined effects of different interleukin-28B gene variants on the outcome of dual combination therapy in chronic hepatitis C virus type 1 infection

(2012) Janett Fischer et al.   HEPATOLOGY

HCV RNA levels in a multiethnic cohort of injection drug users: Human genetic, viral and demographic associations

(2012) Lorenzo Uccellini et al.   HEPATOLOGY

Antiviral strategies in hepatitis C virus infection

(2012) Christoph Sarrazin et al.   JOURNAL OF HEPATOLOGY

c-Fos regulates hepatitis C virus propagation

(2011) Sang-Min Kang et al.   FEBS LETTERS

Polymorphisms Near IL28B and Serologic Response to Peginterferon in HBeAg-Positive Patients With Chronic Hepatitis B

(2011) Milan J. Sonneveld et al.   GASTROENTEROLOGY

Association of gene expression involving innate immunity and genetic variation in interleukin 28B with antiviral response

(2011) Yasuhiro Asahina et al.   HEPATOLOGY

Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures

(2011) Svetlana Marukian et al.   HEPATOLOGY

CCL5: A Double-Edged Sword in Host Defense Against the Hepatitis C Virus

(2011) Antonios Katsounas et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Single nucleotide polymorphism upstream of interleukin 28B associated with phase 1 and phase 2 of early viral kinetics in patients infected with HCV genotype 1

(2011) Charles D. Howell et al.   JOURNAL OF HEPATOLOGY

IL28B rs12979860 Genotype and Spontaneous Clearance of Hepatitis C Virus in a Multi-Ethnic Cohort of Injection Drug Users: Evidence for a Supra-Additive Association

(2011) Fatma M. Shebl et al.   JOURNAL OF INFECTIOUS DISEASES

The dawn of a new era in HCV therapy

(2011) Sandra Ciesek et al.   Nature Reviews Gastroenterology & Hepatology

ENCODE whole-genome data in the UCSC Genome Browser: update 2012

(2011) K. R. Rosenbloom et al.   NUCLEIC ACIDS RESEARCH

Dysregulation of IFN System Can Lead to Poor Response to Pegylated Interferon and Ribavirin Therapy in Chronic Hepatitis C

(2011) Koji Onomoto et al.   PLoS One

Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohort

(2011) Katherine R Smith et al.   Genome Medicine

Structure and function of interleukin-22 and other members of the interleukin-10 family

(2010) Daniela Barretto Barbosa Trivella et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Interleukin-28B Polymorphism Improves Viral Kinetics and Is the Strongest Pretreatment Predictor of Sustained Virologic Response in Genotype 1 Hepatitis C Virus

(2010) Alexander J. Thompson et al.   GASTROENTEROLOGY

Hepatic ISG Expression Is Associated With Genetic Variation in Interleukin 28B and the Outcome of IFN Therapy for Chronic Hepatitis C

(2010) Masao Honda et al.   GASTROENTEROLOGY

Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study

(2010) Andri Rauch et al.   GASTROENTEROLOGY

Interferon-Induced Gene Expression Is a Stronger Predictor of Treatment Response Than IL28B Genotype in Patients With Hepatitis C

(2010) Michael T. Dill et al.   GASTROENTEROLOGY

IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C

(2010) Thomas J. Urban et al.   HEPATOLOGY

Phase 1b study of pegylated interferon lambda 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection

(2010) Andrew J. Muir et al.   HEPATOLOGY

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Structure and Mechanism of Receptor Sharing by the IL-10R2 Common Chain

(2010) Sung-il Yoon et al.   STRUCTURE

CTCF: Master Weaver of the Genome

(2009) Jennifer E. Phillips et al.   CELL

Interferon-λ Is Functionally an Interferon but Structurally Related to the Interleukin-10 Family

(2009) Hans Henrik Gad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

(2009) Dongliang Ge et al.   NATURE

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

(2009) David L. Thomas et al.   NATURE

IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy

(2009) Vijayaprakash Suppiah et al.   NATURE GENETICS

Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

(2009) Yasuhito Tanaka et al.   NATURE GENETICS

Messenger RNA regulation: to translate or to degrade

(2008) Ann-Bin Shyu et al.   EMBO JOURNAL

Analysis of CD8+ T-Cell–Mediated Inhibition of Hepatitis C Virus Replication Using a Novel Immunological Model

(2008) Juandy Jo et al.   GASTROENTEROLOGY

Prolonged Therapy of Advanced Chronic Hepatitis C with Low-Dose Peginterferon

(2008) Adrian M. Di Bisceglie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interferon signaling and treatment outcome in chronic hepatitis C

(2008) M. Sarasin-Filipowicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA