标题
Natural product synthesis in the age of scalability
作者
关键词
-
出版物
NATURAL PRODUCT REPORTS
Volume 31, Issue 4, Pages 419-432
出版商
Royal Society of Chemistry (RSC)
发表日期
2013-12-16
DOI
10.1039/c3np70090a
参考文献
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- (2013) Yasuaki Fukuda et al. ARCHIVES OF PHARMACAL RESEARCH
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- (2013) Silas P Cook Future Medicinal Chemistry
- Isolation and First Total Synthesis of PM050489 and PM060184, Two New Marine Anticancer Compounds
- (2013) María Jesús Martín et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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- (2013) Daniel J. Jansen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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- (2013) Brett A. Granger et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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- (2013) Melvin J. Yu et al. NATURAL PRODUCT REPORTS
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- (2013) Magnus Ronn et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
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- (2013) L. Jorgensen et al. SCIENCE
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- (2013) H. Renata et al. SCIENCE
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- (2013) Ivann Zaragoza Galicia et al. TETRAHEDRON LETTERS
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- (2012) Scott A. Snyder et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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- (2012) Francisco J. Fañanás et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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- (2012) Jun Yin et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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- (2012) François Lévesque et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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- (2012) Sarah-Jane Cozzi et al. ARCHIVES OF DERMATOLOGICAL RESEARCH
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- (2012) JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
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- (2012) George Martin et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
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- (2012) Jing F. Gill et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Correction to Fusarisetin A, an Acinar Morphogenesis Inhibitor from a Soil Fungus, Fusarium sp. FN080326
- (2012) Jae-Hyuk Jang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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- (2012) Mark Lebwohl et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2012) Stephen R. Tudhope et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Fusarisetin A: scalable total synthesis and related studies
- (2012) Jing Xu et al. Chemical Science
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- (2011) Tobias Brückl et al. ACCOUNTS OF CHEMICAL RESEARCH
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- (2011) Timothy Newhouse et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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- (2011) Louis H. Miller et al. CELL
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