Amino Acid Derivatives of Ligustrazine-Oleanolic Acid as New Cytotoxic Agents

Synthesis and antibacterial evaluation of amino acid–antibiotic conjugates

(2014) Mohamed A. Ibrahim et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and Cytotoxic Activities of the Amino Acid-Conjugates of 10-Hydroxycamptothecin

(2014) Guangrong Meng et al.   CHINESE JOURNAL OF ORGANIC CHEMISTRY

Combination of Amino Acid/Dipeptide with Nitric Oxide Donating Oleanolic Acid Derivatives as PepT1 Targeting Antitumor Prodrugs

(2014) Lei Fang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Solid-Phase Library Synthesis of Bi-Functional Derivatives of Oleanolic and Maslinic Acids and Their Cytotoxicity on Three Cancer Cell Lines

(2014) Andres Parra et al.   ACS Combinatorial Science

Antiproliferative and Apoptotic Effects ofSesbania grandifloraLeaves in Human Cancer Cells

(2014) Sankar Pajaniradje et al.   Biomed Research International

Preparation and Evaluation of Solid Dispersions of A New Antitumor Compound Based on Early-Stage Preparation Discovery Concept

(2013) Peng Hou et al.   AAPS PHARMSCITECH

In-vitroandin-vivocomparison of T-OA microemulsions and solid dispersions based on EPDC

(2013) Peng Hou et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Memantine-sulfur containing antioxidant conjugates as potential prodrugs to improve the treatment of Alzheimer’s disease

(2013) Piera Sozio et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Synthesis and Protective Effect of New Ligustrazine-Benzoic Acid Derivatives against CoCl2-Induced Neurotoxicity in Differentiated PC12 Cells

(2013) Penglong Wang et al.   MOLECULES

Discovery of TUG-770: A Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes

(2013) Elisabeth Christiansen et al.   ACS Medicinal Chemistry Letters

Cell survival, DNA damage, and oncogenic transformation after a transient and reversible apoptotic response

(2012) Ho Lam Tang et al.   MOLECULAR BIOLOGY OF THE CELL

Substituted N-Benzylpyrazine-2-carboxamides: Synthesis and Biological Evaluation

(2012) Barbora Servusová et al.   MOLECULES

Synthesis and Biological Evaluation of New Ligustrazine Derivatives as Anti-Tumor Agents

(2012) Penglong Wang et al.   MOLECULES

Lipophilicity in drug discovery

(2010) Michael J Waring   Expert Opinion on Drug Discovery

Lipophilicity and Its Relationship with Passive Drug Permeation

(2010) Xiangli Liu et al.   PHARMACEUTICAL RESEARCH

Gastroprotective Effect and Cytotoxicity of Labdeneamides with Amino Acids

(2010) Guillermo Schmeda-Hirschmann et al.   PLANTA MEDICA

Esters of betulin and betulinic acid with amino acids have improved water solubility and are selectively cytotoxic toward cancer cells

(2009) Malgorzata Drag-Zalesinska et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and evaluation of a novel series of heterocyclic oleanolic acid derivatives with anti-osteoclast formation activity

(2009) Jun-Feng Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Solution- and solid-phase synthesis and anti-HIV activity of maslinic acid derivatives containing amino acids and peptides

(2008) Andres Parra et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The synthesis of ursolic acid derivatives with cytotoxic activity and the investigation of their preliminary mechanism of action

(2008) Yan-Qiu Meng et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structural analysis and antitussive evaluation of five novel esters of verticinone and bile acids

(2008) Jiu-liang Zhang et al.   STEROIDS