Inhibition of RNA Helicase Brr2 by the C-Terminal Tail of the Spliceosomal Protein Prp8

Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system

(2013) J.-B. Fourmann et al.   GENES & DEVELOPMENT

Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre

(2012) Nicolas Rasche et al.   EMBO JOURNAL

Brr2p-mediated conformational rearrangements in the spliceosome during activation and substrate repositioning

(2012) D. Hahn et al.   GENES & DEVELOPMENT

The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA

(2012) S. Mozaffari-Jovin et al.   GENES & DEVELOPMENT

Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome

(2012) K. F. Santos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism for Aar2p function as a U5 snRNP assembly factor

(2011) G. Weber et al.   GENES & DEVELOPMENT

Prognosis for splicing factor PRPF8 retinitis pigmentosa, novel mutations and correlation between human and yeast phenotypes

(2010) Katherine V. Towns et al.   HUMAN MUTATION

Molecular replacement withMOLREP

(2009) Alexei Vagin et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Common Design Principles in the Spliceosomal RNA Helicase Brr2 and in the Hel308 DNA Helicase

(2009) Vladimir Pena et al.   MOLECULAR CELL

Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2

(2009) Lingdi Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure and function of an RNase H domain at the heart of the spliceosome

(2008) Vladimir Pena et al.   EMBO JOURNAL

ATP-dependent unwinding of U4/U6 snRNAs by the Brr2 helicase requires the C terminus of Prp8

(2008) Corina Maeder et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A role for ubiquitin in the spliceosome assembly pathway

(2008) Priya Bellare et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY