Therapeutic potential of nucleic acid-binding isoquinoline alkaloids: Binding aspects and implications for drug design

Fluorescence properties of selected benzo[c]phenantridine alkaloids and studies of their interaction with CT DNA

(2009) Jana Urbanová et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Small molecule–RNA interaction: Spectroscopic and calorimetric studies on the binding by the cytotoxic protoberberine alkaloid coralyne to single stranded polyribonucleotides

(2009) Md. Maidul Islam et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Berberine Exerts Neuroprotective Actions against in Vitro Ischemia-Induced Neuronal Cell Damage in Organotypic Hippocampal Slice Cultures: Involvement of B-Cell Lymphoma 2 Phosphorylation Suppression

(2009) Hu-Shan Cui et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Interaction of Isoquinoline Alkaloids with Polymorphic DNA Structures

(2009) Kakali Bhadra et al.   CHEMISTRY & BIODIVERSITY

Molecular Aspects of Small Molecules-Poly(A) Interaction: An Approach to RNA Based Drug Design

(2009) Prabal Giri et al.   CURRENT MEDICINAL CHEMISTRY

Protective effect of berberine on beta cells in streptozotocin- and high-carbohydrate/high-fat diet-induced diabetic rats

(2009) Jiyin Zhou et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effect of berberine on Staphylococcus epidermidis biofilm formation

(2009) Xiaoqing Wang et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Synthesis and antimicrobial activity of 3-octyloxy-8-alkyljatrorrhizine derivatives

(2009) Li-Jun Wang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Spectroscopic and Calorimetric Studies on the Binding of Alkaloids Berberine, Palmatine and Coralyne to Double Stranded RNA Polynucleotides

(2009) Md. Maidul Islam et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Interaction of Isoquinoline Alkaloids with an RNA Triplex: Structural and Thermodynamic Studies of Berberine, Palmatine, and Coralyne Binding to Poly(U).Poly(A)*Poly(U)

(2009) Rangana Sinha et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Berberine induces p53-dependent cell cycle arrest and apoptosis of human osteosarcoma cells by inflicting DNA damage

(2009) Zhaojian Liu et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Berberine inhibits human tongue squamous carcinoma cancer tumor growth in a murine xenograft model

(2009) Yung-Tsuan Ho et al.   PHYTOMEDICINE

Self-structure induction in single stranded poly(A) by small molecules: Studies on DNA intercalators, partial intercalators and groove binding molecules

(2008) Prabal Giri et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Berberine–DNA complexation: New insights into the cooperative binding and energetic aspects

(2008) Kakali Bhadra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Palmatine, a protoberberine alkaloid, inhibits both Ca2+- and cAMP-activated Cl− secretion in isolated rat distal colon

(2008) D Z Wu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Sanguinarine causes DNA damage and p53-independent cell death in human colon cancer cell lines

(2008) Smita S. Matkar et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Anti-invasive activity of sanguinarine through modulation of tight junctions and matrix metalloproteinase activities in MDA-MB-231 human breast carcinoma cells

(2008) Yung Hyun Choi et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Interaction of Isoquinoline Alkaloid Palmatine with Deoxyribonucleic Acids: Binding Heterogeneity, and Conformational and Thermodynamic Aspects

(2008) Kakali Bhadra et al.   CHEMISTRY & BIODIVERSITY

Sanguinarine, a Benzophenanthridine Alkaloid, Induces Apoptosis in MDA-MB-231 Human Breast Carcinoma Cells through a Reactive Oxygen Species-Mediated Mitochondrial Pathway

(2008) Woo Young Choi et al.   CHEMOTHERAPY

Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I: A Mechanism for the Action of Berberine to Activate AMP-Activated Protein Kinase and Improve Insulin Action

(2008) N. Turner et al.   DIABETES

Binding of berberine to human telomeric quadruplex - spectroscopic, calorimetric and molecular modeling studies

(2008) Amit Arora et al.   FEBS Journal

DNA binding of benzophenanthridine compounds sanguinarine versus ethidium: Comparative binding and thermodynamic profile of intercalation

(2008) Maidul Hossain et al.   JOURNAL OF CHEMICAL THERMODYNAMICS

Energetics of the binding of phototoxic and cytotoxic plant alkaloid sanguinarine to DNA: Isothermal titration calorimetric studies

(2008) Anupam Adhikari et al.   JOURNAL OF MOLECULAR STRUCTURE

Binding of DNA-binding alkaloids berberine and palmatine to tRNA and comparison to ethidium: Spectroscopic and molecular modeling studies

(2008) Md. Maidul Islam et al.   JOURNAL OF MOLECULAR STRUCTURE

Solvent Effects on the Thermodynamics and Kinetics of Coralyne Self-Aggregation

(2008) Begoña García et al.   JOURNAL OF PHYSICAL CHEMISTRY B

RNA targeting through binding of small molecules: Studies on t-RNA binding by the cytotoxic protoberberine alkaloidcoralyne

(2008) Md. Maidul Islam et al.   Molecular BioSystems

Molecular recognition of poly(A) by small ligands: an alternative method of analysis reveals nanomolar, cooperative and shape-selective binding

(2008) Özgül Persil Çetinkol et al.   NUCLEIC ACIDS RESEARCH

Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine

(2008) Mohsen Imanshahidi et al.   PHYTOTHERAPY RESEARCH

Synthesis and Antimicrobial Activity of 3-Alkoxyjatrorrhizine Derivatives

(2008) Li-jun Wang et al.   PLANTA MEDICA

Study on the phosphorescence characterizations of palmatine chloride on the solid substrate and its interaction with ctDNA

(2008) J LI et al.   TALANTA

Sanguinarine induces apoptosis in A549 human lung cancer cells primarily via cellular glutathione depletion

(2008) Byeong-Churl Jang et al.   TOXICOLOGY IN VITRO

Thermodynamics of the binding of cytotoxic protoberberine molecule coralyne to deoxyribonucleic acids

(2007) Kakali Bhadra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

RNA targeting by small molecule alkaloids: Studies on the binding of berberine and palmatine to polyribonucleotides and comparison to ethidium

(2007) Md. Maidul Islam et al.   JOURNAL OF MOLECULAR STRUCTURE

Spectroscopic and calorimetric studies on the binding of the phototoxic and cytotoxic plant alkaloid sanguinarine with double helical poly(A)

(2007) Prabal Giri et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY