Covalent Growth Factor Immobilization Strategies for Tissue Repair and Regeneration

A review of the literature on topical therapies for diabetic foot ulcers. Part 2: advanced treatments

(2014) R. White et al.   Journal of Wound Care

Regulation of keratinocyte signaling and function via changes in epidermal growth factor presentation

(2010) Tracy J. Puccinelli et al.   Acta Biomaterialia

Nerve growth factor (NGF)-conjugated electrospun nanostructures with topographical cues for neuronal differentiation of mesenchymal stem cells

(2010) Young Il Cho et al.   Acta Biomaterialia

Covalently immobilized platelet-derived growth factor-BB promotes angiogenesis in biomimetic poly(ethylene glycol) hydrogels

(2010) Jennifer E. Saik et al.   Acta Biomaterialia

Improved cellularization and angiogenesis using collagen scaffolds chemically conjugated with vascular endothelial growth factor

(2010) Qifen He et al.   Acta Biomaterialia

The use of vascular endothelial growth factor functionalized agarose to guide pluripotent stem cell aggregates toward blood progenitor cells

(2010) Nafees Rahman et al.   BIOMATERIALS

Differentiation of pre-osteoblast cells on poly(ethylene terephthalate) grafted with RGD and/or BMPs mimetic peptides

(2010) Omar F. Zouani et al.   BIOMATERIALS

Bioactive modification of poly(ethylene glycol) hydrogels for tissue engineering

(2010) Junmin Zhu   BIOMATERIALS

Toward delivery of multiple growth factors in tissue engineering

(2010) Fa-Ming Chen et al.   BIOMATERIALS

Differentiation of neural stem cells in three-dimensional growth factor-immobilized chitosan hydrogel scaffolds

(2010) Nic D. Leipzig et al.   BIOMATERIALS

Biodegradable collagen patch with covalently immobilized VEGF for myocardial repair

(2010) Yasuo Miyagi et al.   BIOMATERIALS

Vascular Endothelial Growth Factor as an Anti-Angiogenic Target for Cancer Therapy

(2010) Gang Niu et al.   CURRENT DRUG TARGETS

Benefit-Risk Assessment of Becaplermin in the Treatment of Diabetic Foot Ulcers

(2010) Nikolaos Papanas et al.   DRUG SAFETY

TGF-β3 immobilized PLGA-gelatin/chondroitin sulfate/hyaluronic acid hybrid scaffold for cartilage regeneration

(2010) Hongbin Fan et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Defining conditions for covalent immobilization of angiogenic growth factors onto scaffolds for tissue engineering

(2010) Loraine L.Y. Chiu et al.   Journal of Tissue Engineering and Regenerative Medicine

Binding to the Extracellular Matrix and Proteolytic Processing: Two Key Mechanisms Regulating Vascular Endothelial Growth Factor Action

(2010) Napoleone Ferrara   MOLECULAR BIOLOGY OF THE CELL

Immobilization of growth factors on solid supports for the modulation of stem cell fate

(2010) Tilo Pompe et al.   Nature Protocols

Chemically-Conjugated Bone Morphogenetic Protein-2 on Three-Dimensional Polycaprolactone Scaffolds Stimulates Osteogenic Activity in Bone Marrow Stromal Cells

(2010) Huina Zhang et al.   TISSUE ENGINEERING PART A

Micron-Scale Spatially Patterned, Covalently Immobilized Vascular Endothelial Growth Factor on Hydrogels Accelerates Endothelial Tubulogenesis and Increases Cellular Angiogenic Responses

(2010) Julia E. Leslie-Barbick et al.   TISSUE ENGINEERING PART A

Engineering surfaces for site-specific vascular differentiation of mouse embryonic stem cells

(2009) C. Katherine Chiang et al.   Acta Biomaterialia

Epidermal Growth Factor Tethered through Coiled-Coil Interactions Induces Cell Surface Receptor Phosphorylation

(2009) Cyril Boucher et al.   BIOCONJUGATE CHEMISTRY

Direct Chemical Cross-Linking of Platelet-Derived Growth Factor-BB to the Demineralized Bone Matrix Improves Cellularization and Vascularization

(2009) Lei Chen et al.   BIOMACROMOLECULES

Surface Functionalization of Titanium with Carboxymethyl Chitosan and Immobilized Bone Morphogenetic Protein-2 for Enhanced Osseointegration

(2009) Zhilong Shi et al.   BIOMACROMOLECULES

The bioactivity of rhBMP-2 immobilized poly(lactide-co-glycolide) scaffolds

(2009) Hong Shen et al.   BIOMATERIALS

The phosphorylation of vascular endothelial growth factor receptor-2 (VEGFR-2) by engineered surfaces with electrostatically or covalently immobilized VEGF

(2009) Sean M. Anderson et al.   BIOMATERIALS

The use of immobilized osteogenic growth peptide on gradient substrates synthesized via click chemistry to enhance MC3T3-E1 osteoblast proliferation

(2009) Nicole M. Moore et al.   BIOMATERIALS

The effect of VEGF functionalization of titanium on endothelial cells in vitro

(2009) Chye Khoon Poh et al.   BIOMATERIALS

Scaffolds with covalently immobilized VEGF and Angiopoietin-1 for vascularization of engineered tissues

(2009) Loraine L.Y. Chiu et al.   BIOMATERIALS

Synergistic effect of immobilized laminin and nerve growth factor on PC12 neurite outgrowth

(2009) Anil Kumar H. Achyuta et al.   BIOTECHNOLOGY PROGRESS

Covalently-Immobilized Vascular Endothelial Growth Factor Promotes Endothelial Cell Tubulogenesis in Poly(ethylene glycol) Diacrylate Hydrogels

(2009) Julia E. Leslie-Barbick et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Sustained epidermal growth factor receptor levels and activation by tethered ligand binding enhances osteogenic differentiation of multi-potent marrow stromal cells

(2009) Manu O. Platt et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Three-Dimensional Nanofibrous Scaffolds Incorporating Immobilized BDNF Promote Proliferation and Differentiation of Cortical Neural Stem Cells

(2009) Malcolm K. Horne et al.   STEM CELLS AND DEVELOPMENT

Biopolymer-Based Growth Factor Delivery for Tissue Repair: From Natural Concepts to Engineered Systems

(2009) Lorenz Uebersax et al.   TISSUE ENGINEERING PART B-REVIEWS

Immobilization of glycoproteins, such as VEGF, on biodegradable substrates

(2008) J.L. Sharon et al.   Acta Biomaterialia

Vascular endothelial growth factor immobilized in collagen scaffold promotes penetration and proliferation of endothelial cells

(2008) Yi Hao Shen et al.   Acta Biomaterialia

Directed differentiation of pancreatic stem cells by soluble and immobilised signalling factors

(2008) Claudia Brose et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Co-Immobilization of Gradient-Patterned Growth Factors for Directed Cell Migration

(2008) Tracy Jane Stefonek-Puccinelli et al.   ANNALS OF BIOMEDICAL ENGINEERING

The effect of immobilized platelet derived growth factor AA on neural stem/progenitor cell differentiation on cell-adhesive hydrogels

(2008) Yukie Aizawa et al.   BIOMATERIALS

The immobilization of basic fibroblast growth factor on plasma-treated poly(lactide-co-glycolide)

(2008) Hong Shen et al.   BIOMATERIALS

Evaluation of RGD- or EGF-immobilized chitosan scaffolds for chondrogenic activity

(2008) R. Seda Tiğli et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Immobilized recombinant human bone morphogenetic protein-2 enhances the phosphorylation of receptor-activated Smads

(2008) Eiki Yamachika et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Treating the chronic wound: A practical approach to the care of nonhealing wounds and wound care dressings

(2008) Margaret A. Fonder et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Effect of Grafting RGD and BMP-2 Protein-Derived Peptides to a Hydrogel Substrate on Osteogenic Differentiation of Marrow Stromal Cells

(2008) Xuezhong He et al.   LANGMUIR

Functional immobilization of signaling proteins enables control of stem cell fate

(2008) Kristin Alberti et al.   NATURE METHODS

PEG Hydrogels for the Controlled Release of Biomolecules in Regenerative Medicine

(2008) Chien-Chi Lin et al.   PHARMACEUTICAL RESEARCH

PERSPECTIVE ARTICLE: Growth factors and cytokines in wound healing

(2008) Stephan Barrientos et al.   WOUND REPAIR AND REGENERATION

In vivo wound healing of diabetic ulcers using electrospun nanofibers immobilized with human epidermal growth factor (EGF)

(2007) Ji Suk Choi et al.   BIOMATERIALS

Covalently immobilized biosignal molecule materials for tissue engineering

(2007) Yoshihiro Ito   Soft Matter