On the dynamics of neutral mutations in a mathematical model for a homogeneous stem cell population

Chronic myelogenous leukemia stem and progenitor cells demonstrate chromosomal instability related to repeated breakage-fusion-bridge cycles mediated by increased nonhomologous end joining

(2012) S. Chakraborty et al.   BLOOD

Rac2-MRC-cIII-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors

(2012) M. Nieborowska-Skorska et al.   BLOOD

Defining the mode of tumour growth by clonal analysis

(2012) Gregory Driessens et al.   NATURE

Deregulated expression of HMGA2 is implicated in clonal expansion of PIGA deficient cells in paroxysmal nocturnal haemoglobinuria

(2011) Yoshiko Murakami et al.   BRITISH JOURNAL OF HAEMATOLOGY

Eculizumab treatment modifies the immune profile of PNH patients

(2011) Fiorella Alfinito et al.   IMMUNOBIOLOGY

A compact result for the time-dependent probability of fixation at a neutral locus

(2011) D. Waxman   JOURNAL OF THEORETICAL BIOLOGY

Somatic mutations and the hierarchy of hematopoiesis

(2010) Arne Traulsen et al.   BIOESSAYS

BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cells

(2010) M. Schemionek et al.   BLOOD

Reproductive fitness advantage of BCR–ABL expressing leukemia cells

(2010) Arne Traulsen et al.   CANCER LETTERS

Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity

(2010) Amie S. Corbin et al.   JOURNAL OF CLINICAL INVESTIGATION

Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein

(2010) M. Jaras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The pathophysiology of paroxysmal nocturnal hemoglobinuria and treatment with eculizumab

(2010) Richard Kelly   Therapeutics and Clinical Risk Management

Progenitor cell self-renewal and cyclic neutropenia

(2009) D.  Dingli et al.   CELL PROLIFERATION

Tyrosine kinase inhibitor therapy can cure chronic myeloid leukemia without hitting leukemic stem cells

(2009) T. Lenaerts et al.   HAEMATOLOGICA

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

Fixation times in evolutionary games under weak selection

(2009) Philipp M Altrock et al.   NEW JOURNAL OF PHYSICS

Fluctuating selection: the perpetual renewal of adaptation in variable environments

(2009) G. Bell   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Is Tumor Growth Sustained by Rare Cancer Stem Cells or Dominant Clones?

(2008) J. M. Adams et al.   CANCER RESEARCH

Multiple mutant clones in blood rarely coexist

(2008) David Dingli et al.   PHYSICAL REVIEW E

Neutral evolution in paroxysmal nocturnal hemoglobinuria

(2008) D. Dingli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA