Chronic myelogenous leukemia stem and progenitor cells demonstrate chromosomal instability related to repeated breakage-fusion-bridge cycles mediated by increased nonhomologous end joining

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

(2011) Philip J. Stephens et al.   CELL

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

Different outcomes of telomere-dependent anaphase bridges

(2010) Laura Tusell et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

BCR/ABL Stimulates WRN to Promote Survival and Genomic Instability

(2010) A. Slupianek et al.   CANCER RESEARCH

Chronic myeloid leukemia: mechanisms of blastic transformation

(2010) Danilo Perrotti et al.   JOURNAL OF CLINICAL INVESTIGATION

Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4

(2010) Cristian Boboila et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inhibition of Grb2 expression demonstrates an important role in BCR–ABL-mediated MAPK activation and transformation of primary human hematopoietic cells

(2010) H Modi et al.   LEUKEMIA

Dangerous Liaisons: Fanconi Anemia and Toxic Nonhomologous End Joining in DNA Crosslink Repair

(2010) Samuel F. Bunting et al.   MOLECULAR CELL

Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells

(2010) M. Fenech et al.   MUTAGENESIS

Mechanisms of double-strand break repair in somatic mammalian cells

(2009) Andrea J. Hartlerode et al.   BIOCHEMICAL JOURNAL

Up-regulation of WRN and DNA ligase III  in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks

(2008) A. Sallmyr et al.   BLOOD

BCR/ABL induces chromosomal instability after genotoxic stress and alters the cell death threshold

(2008) J Dierov et al.   LEUKEMIA

BCR/ABL promotes accumulation of chromosomal aberrations induced by oxidative and genotoxic stress

(2008) M Koptyra et al.   LEUKEMIA

Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair

(2008) Nicole Bennardo et al.   PLoS Genetics