Drainage of Cells and Soluble Antigen from the CNS to Regional Lymph Nodes

Low-Dose Tolerance Is Mediated by the Microfold Cell Ligand, Reovirus Protein  1

(2014) A. Rynda et al.   JOURNAL OF IMMUNOLOGY

Intrinsic and Induced Regulation of the Age-Associated Onset of Spontaneous Experimental Autoimmune Encephalomyelitis

(2014) H. Zhang et al.   JOURNAL OF IMMUNOLOGY

Swift Entry of Myelin-Specific T Lymphocytes into the Central Nervous System in Spontaneous Autoimmune Encephalomyelitis

(2014) G. C. Furtado et al.   JOURNAL OF IMMUNOLOGY

MHC class I–restricted myelin epitopes are cross-presented by Tip-DCs that promote determinant spreading to CD8+ T cells

(2013) Qingyong Ji et al.   NATURE IMMUNOLOGY

Site-specific accumulation of recently activated CD4+Foxp3+ regulatory T cells following adoptive transfer

(2012) Scott M. Lieberman et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Dendritic Cells Ameliorate Autoimmunity in the CNS by Controlling the Homeostasis of PD-1 Receptor+ Regulatory T Cells

(2012) Nir Yogev et al.   IMMUNITY

Dendritic Cells and Multiple Sclerosis: Disease, Tolerance and Therapy

(2012) Mohammad Mohammad et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CD4+LAP+ and CD4+CD25+Foxp3+ Regulatory T Cells Induced by Nasal Oxidized Low-Density Lipoprotein Suppress Effector T Cells Response and Attenuate Atherosclerosis in ApoE−/− Mice

(2012) Yucheng Zhong et al.   JOURNAL OF CLINICAL IMMUNOLOGY

B cell exchange across the blood-brain barrier in multiple sclerosis

(2012) H.-Christian von Büdingen et al.   JOURNAL OF CLINICAL INVESTIGATION

Zinc finger transcription factor zDC is a negative regulator required to prevent activation of classical dendritic cells in the steady state

(2012) Matthew M. Meredith et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Brain-Derived Antigens in Lymphoid Tissue of Patients with Acute Stroke

(2012) A. M. Planas et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells Selectively Preserve Immune Privilege of Self-Antigens during Viral Central Nervous System Infection

(2012) L. Cervantes-Barragan et al.   JOURNAL OF IMMUNOLOGY

Editorial: Route by which monocytes leave the brain is revealed

(2012) Jon D. Laman et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Migration of monocytes after intracerebral injection at entorhinal cortex lesion site

(2012) Miriam Kaminski et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Detecting and Treating Cancer with Nanotechnology

(2012) Keith B. Hartman et al.   Molecular Diagnosis & Therapy

Induction of immune tolerance in mice with a novel mucosal nanoemulsion adjuvant and self-antigen

(2012) Su He Wang et al.   Nanomedicine

T cells become licensed in the lung to enter the central nervous system

(2012) Francesca Odoardi et al.   NATURE

Primary oligodendrocyte death does not elicit anti-CNS immunity

(2012) Giuseppe Locatelli et al.   NATURE NEUROSCIENCE

Animal models of multiple sclerosis: the good, the bad and the bottom line

(2012) Richard M Ransohoff   NATURE NEUROSCIENCE

Immune surveillance in the central nervous system

(2012) Shalina S Ousman et al.   NATURE NEUROSCIENCE

The immunology of acute stroke

(2012) Ángel Chamorro et al.   Nature Reviews Neurology

Disruption of Arterial Perivascular Drainage of Amyloid-β from the Brains of Mice Expressing the Human APOE ε4 Allele

(2012) Cheryl A. Hawkes et al.   PLoS One

Dendritic Cells from Oral Cavity Induce Foxp3+ Regulatory T Cells upon Antigen Stimulation

(2012) Sayuri Yamazaki et al.   PLoS One

ApoE-Directed Therapeutics Rapidly Clear  -Amyloid and Reverse Deficits in AD Mouse Models

(2012) P. E. Cramer et al.   SCIENCE

Viral and Inflammatory Triggers of Neurodegenerative Diseases

(2012) M. Deleidi et al.   Science Translational Medicine

Reversal of Paralysis and Reduced Inflammation from Peripheral Administration of  -Amyloid in TH1 and TH17 Versions of Experimental Autoimmune Encephalomyelitis

(2012) J. L. Grant et al.   Science Translational Medicine

A Dense Poly(Ethylene Glycol) Coating Improves Penetration of Large Polymeric Nanoparticles Within Brain Tissue

(2012) E. A. Nance et al.   Science Translational Medicine

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Neck Lymph Nodes in Chronic Autoimmune Thyroiditis: The Sonographic Pattern

(2012) Davide Brancato et al.   THYROID

Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy

(2011) Cheryl A. Hawkes et al.   ACTA NEUROPATHOLOGICA

Induction of Tolerance via the Sublingual Route: Mechanisms and Applications

(2011) Philippe Moingeon et al.   Clinical & Developmental Immunology

Oral macrophage-like cells play a key role in tolerance induction following sublingual immunotherapy of asthmatic mice

(2011) L Mascarell et al.   Mucosal Immunology

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination

(2011) Kerstin Berer et al.   NATURE

Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

(2011) Marco Prinz et al.   NATURE NEUROSCIENCE

PLGA, PLGA-TMC and TMC-TPP Nanoparticles Differentially Modulate the Outcome of Nasal Vaccination by Inducing Tolerance or Enhancing Humoral Immunity

(2011) Chantal Keijzer et al.   PLoS One

CNS-derived CCL21 is both sufficient to drive homeostatic CD4+ T cell proliferation and necessary for efficient CD4+ T cell migration into the CNS parenchyma following Toxoplasma gondii infection

(2010) Corinne C. Ploix et al.   BRAIN BEHAVIOR AND IMMUNITY

Identification of Regulatory Foxp3+ Invariant NKT Cells Induced by TGF- 

(2010) M. Monteiro et al.   JOURNAL OF IMMUNOLOGY

Central Nervous System Demyelinating Disease Protection by the Human Commensal Bacteroides fragilis Depends on Polysaccharide A Expression

(2010) J. Ochoa-Reparaz et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells Inhibit T Cell Proliferation and Decrease Demyelination in Mice Chronically Infected with a Coronavirus

(2010) K. Trandem et al.   JOURNAL OF IMMUNOLOGY

Novel Characterization of Monocyte-Derived Cell Populations in the Meninges and Choroid Plexus and Their Rates of Replenishment in Bone Marrow Chimeric Mice

(2010) Holly R. Chinnery et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease

(2010) J Ochoa-Repáraz et al.   Mucosal Immunology

Turning over the Chance card on MS susceptibility

(2010) Richard M Ransohoff   NATURE IMMUNOLOGY

Viral infection triggers central nervous system autoimmunity via activation of CD8+ T cells expressing dual TCRs

(2010) Qingyong Ji et al.   NATURE IMMUNOLOGY

Dynamics and fate of USPIO in the central nervous system in experimental autoimmune encephalomyelitis

(2010) Raoul D. Oude Engberink et al.   NMR IN BIOMEDICINE

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Superparamagnetic Iron Oxide Nanoparticles: Diagnostic Magnetic Resonance Imaging and Potential Therapeutic Applications in Neurooncology and Central Nervous System Inflammatory Pathologies, a Review

(2009) Jason S Weinstein et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The lung vascular filter as a site of immune induction for T cell responses to large embolic antigen

(2009) Monique A.M. Willart et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD11c+CD8 + Dendritic Cells Promote Protective Immunity to Respiratory Infection with Bordetella pertussis

(2009) P. J. Dunne et al.   JOURNAL OF IMMUNOLOGY

Role of Gut Commensal Microflora in the Development of Experimental Autoimmune Encephalomyelitis

(2009) J. Ochoa-Reparaz et al.   JOURNAL OF IMMUNOLOGY

Selective targeting of perivascular macrophages for clearance of  -amyloid in cerebral amyloid angiopathy

(2009) C. A. Hawkes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lymphatic drainage of the brain and the pathophysiology of neurological disease

(2008) Roy O. Weller et al.   ACTA NEUROPATHOLOGICA

After Injection into the Striatum, in Vitro-Differentiated Microglia- and Bone Marrow-Derived Dendritic Cells Can Leave the Central Nervous System via the Blood Stream

(2008) Sonja Hochmeister et al.   AMERICAN JOURNAL OF PATHOLOGY

A nasal proteosome adjuvant activates microglia and prevents amyloid deposition

(2008) Dan Frenkel et al.   ANNALS OF NEUROLOGY

Mucosal Tolerance to E-Selectin Promotes the Survival of Newly Generated Neuroblasts via Regulatory T-Cell Induction after Stroke in Spontaneously Hypertensive Rats

(2008) Satoru Ishibashi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain

(2008) Karen Bulloch et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Brain antigens in functionally distinct antigen-presenting cell populations in cervical lymph nodes in MS and EAE

(2008) Marloes van Zwam et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Surgical excision of CNS-draining lymph nodes reduces relapse severity in chronic-relapsing experimental autoimmune encephalomyelitis

(2008) Marloes van Zwam et al.   JOURNAL OF PATHOLOGY

Immune cell entry into the central nervous system: Involvement of adhesion molecules and chemokines

(2008) Britta Engelhardt   JOURNAL OF THE NEUROLOGICAL SCIENCES

Abundant extracellular myelin in the meninges of patients with multiple sclerosis

(2008) E.-J. Kooi et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Cerebrospinal Fluid Dendritic Cells Infiltrate the Brain Parenchyma and Target the Cervical Lymph Nodes under Neuroinflammatory Conditions

(2008) Eric Hatterer et al.   PLoS One