What have we learned from the streptozotocin-induced animal model of sporadic Alzheimer’s disease, about the therapeutic strategies in Alzheimer’s research
出版年份 2012 全文链接
标题
What have we learned from the streptozotocin-induced animal model of sporadic Alzheimer’s disease, about the therapeutic strategies in Alzheimer’s research
作者
关键词
Intracerebroventricular streptozotocin, Non-transgenic rat model, Sporadic Alzheimer’s disease, Therapeutic strategies
出版物
JOURNAL OF NEURAL TRANSMISSION
Volume 120, Issue 1, Pages 233-252
出版商
Springer Nature
发表日期
2012-08-11
DOI
10.1007/s00702-012-0877-9
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Modeling Sporadic Alzheimer's Disease: The Insulin Resistant Brain State Generates Multiple Long-Term Morphobiological Abnormalities Including Hyperphosphorylated Tau Protein and Amyloid-β
- (2017) Melita Salkovic-Petrisic et al. JOURNAL OF ALZHEIMERS DISEASE
- Hippocampal Alterations in Rats Submitted to Streptozotocin-Induced Dementia Model are Prevented by Aminoguanidine
- (2017) Letícia Rodrigues et al. JOURNAL OF ALZHEIMERS DISEASE
- Carvedilol Reestablishes Long-Term Potentiation in a Mouse Model of Alzheimer's Disease
- (2017) Isabel Arrieta-Cruz et al. JOURNAL OF ALZHEIMERS DISEASE
- A Multi-Center Randomized Proof-of-Concept Clinical Trial Applying [18F]FDG-PET for Evaluation of Metabolic Therapy with Rosiglitazone XR in Mild to Moderate Alzheimer's Disease
- (2017) Sofia Tzimopoulou et al. JOURNAL OF ALZHEIMERS DISEASE
- Treating transgenic Alzheimer mice with a β-secretase inhibitor, what have we learned?
- (2016) Jordan Tang et al. Aging-US
- Memory restorative role of statins in experimental dementia: an evidence of their cholesterol dependent and independent actions
- (2014) Yogita Dalla et al. Pharmacological Reports
- The Novel Multi-Target Iron Chelating-Radical Scavenging Compound M30 Possesses Beneficial Effects on Major Hallmarks of Alzheimer's Disease
- (2012) Lana Kupershmidt et al. ANTIOXIDANTS & REDOX SIGNALING
- Antioxidants for Alzheimer Disease
- (2012) Douglas R. Galasko et al. ARCHIVES OF NEUROLOGY
- Cognitive decline in STZ-3V rats is largely due to dysfunctional insulin signalling through the dentate gyrus
- (2012) Akiko Sheala Shingo et al. BEHAVIOURAL BRAIN RESEARCH
- The role of iron as a mediator of oxidative stress in Alzheimer disease
- (2012) Rudy J. Castellani et al. BIOFACTORS
- Glycogen Synthase Kinase-3 (GSK-3) Inhibitors for the Treatment of Alzheimers Disease
- (2012) Miguel Medina et al. CURRENT PHARMACEUTICAL DESIGN
- Neuroprotection by the multitarget iron chelator M30 on age-related alterations in mice
- (2012) Lana Kupershmidt et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type
- (2012) H. Javed et al. NEUROSCIENCE
- Neuroprotective effect of RO-20-1724-a phosphodiesterase4 inhibitor against intracerebroventricular streptozotocin induced cognitive deficit and oxidative stress in rats
- (2012) Vivek Sharma et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Amelioration of neurodegenerative changes in cellular and rat models of diabetes-related Alzheimer’s disease by exendin-4
- (2011) Song Chen et al. AGE
- Insulin-resistant brain state: The culprit in sporadic Alzheimer's disease?
- (2011) Sónia C. Correia et al. AGEING RESEARCH REVIEWS
- Extended results of the Alzheimer’s disease anti-inflammatory prevention trial
- (2011) John C. Breitner et al. Alzheimers & Dementia
- Cholesterol Level and Statin Use in Alzheimer Disease
- (2011) Nina E. Shepardson ARCHIVES OF NEUROLOGY
- Cholesterol Level and Statin Use in Alzheimer Disease
- (2011) Nina E. Shepardson ARCHIVES OF NEUROLOGY
- Improvement of brain energy metabolism and cholinergic functions contributes to the beneficial effects of silibinin against streptozotocin induced memory impairment
- (2011) Santoshkumar Tota et al. BEHAVIOURAL BRAIN RESEARCH
- ICV STZ induced impairment in memory and neuronal mitochondrial function: A protective role of nicotinic receptor
- (2011) Gunjan Saxena et al. BEHAVIOURAL BRAIN RESEARCH
- Lithium, phenserine, memantine and pioglitazone reverse memory deficit and restore phospho-GSK3β decreased in hippocampus in intracerebroventricular streptozotocin induced memory deficit model
- (2011) Teresa Ponce-Lopez et al. BRAIN RESEARCH
- Disease-modifying properties of long-term lithium treatment for amnestic mild cognitive impairment: randomised controlled trial
- (2011) Orestes V. Forlenza et al. BRITISH JOURNAL OF PSYCHIATRY
- Neuroprotector effect of p,p'-methoxyl-diphenyl diselenide in a model of sporadic dementia of Alzheimer's type in mice: contribution of antioxidant mechanism
- (2011) Simone Pinton et al. CELL BIOCHEMISTRY AND FUNCTION
- Rosiglitazone Does Not Improve Cognition or Global Function when Used as Adjunctive Therapy to AChE Inhibitors in Mild-to-Moderate Alzheimers Disease: Two Phase 3 Studies
- (2011) C. Harrington et al. Current Alzheimer Research
- Modulation of nitrergic pathway by sesamol prevents cognitive deficits and associated biochemical alterations in intracerebroventricular streptozotocin administered rats
- (2011) Shubham Misra et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- (Val8) glucagon-like peptide-1 prevents tau hyperphosphorylation, impairment of spatial learning and ultra-structural cellular damage induced by streptozotocin in rat brains
- (2011) Lin Li et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Insulin receptor signaling in rat hippocampus: A study in STZ (ICV) induced memory deficit model
- (2011) Rahul Agrawal et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Perindopril, a centrally active angiotensin-converting enzyme inhibitor, prevents cognitive impairment in mouse models of Alzheimer's disease
- (2011) Yi-Fei Dong et al. FASEB JOURNAL
- Possible implications of insulin resistance and glucose metabolism in Alzheimer’s disease pathogenesis
- (2011) Domenico Bosco et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Differential role of cyclooxygenase isozymes on neuronal density in hippocampus CA1 region of intracerebroventricular streptozotocin treated rat brain
- (2011) Dinesh K. Dhull et al. JOURNAL OF CHEMICAL NEUROANATOMY
- Neuroprotective Effect of Cyclooxygenase Inhibitors in ICV-STZ Induced Sporadic Alzheimer’s Disease in Rats
- (2011) Dinesh Kumar Dhull et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- The neuroprotective effect of two statins: simvastatin and pravastatin on a streptozotocin-induced model of Alzheimer’s disease in rats
- (2011) Ana Carolina Tramontina et al. JOURNAL OF NEURAL TRANSMISSION
- Cerebral amyloid angiopathy in streptozotocin rat model of sporadic Alzheimer’s disease: a long-term follow up study
- (2011) Melita Salkovic-Petrisic et al. JOURNAL OF NEURAL TRANSMISSION
- Developing β-secretase inhibitors for treatment of Alzheimer’s disease
- (2011) Arun K. Ghosh et al. JOURNAL OF NEUROCHEMISTRY
- Melatonin treatment restores mitochondrial function in Alzheimer’s mice: a mitochondrial protective role of melatonin membrane receptor signaling
- (2011) Natasa Dragicevic et al. JOURNAL OF PINEAL RESEARCH
- Molecular mechanisms linking diabetes mellitus and Alzheimer disease: beta-amyloid peptide, insulin signaling, and neuronal function
- (2011) Shuko Takeda et al. Molecular BioSystems
- Novel molecular targets of the neuroprotective/neurorescue multimodal iron chelating drug M30 in the mouse brain
- (2011) L. Kupershmidt et al. NEUROSCIENCE
- Changes in hippocampal synapses and learning-memory abilities in a streptozotocin-treated rat model and intervention by using fasudil hydrochloride
- (2011) Y. Hou et al. NEUROSCIENCE
- 2.14.3 NEURORESTORATIVE, NEUROPROTECTIVE AND CELL CYCLE ARREST ACTIVITY OF NOVEL MULTI TARGET DRUGS IN ANIMAL MODELS OF PARKINSON'S DISEASE
- (2011) M.B.H. Youdim PARKINSONISM & RELATED DISORDERS
- A Randomized Pilot Clinical Trial of the Safety of Pioglitazone in Treatment of Patients With Alzheimer Disease
- (2010) David S. Geldmacher et al. ARCHIVES OF NEUROLOGY
- Protective effect of quercetin against intracerebral streptozotocin induced reduction in cerebral blood flow and impairment of memory in mice
- (2010) Santoshkumar Tota et al. BEHAVIOURAL BRAIN RESEARCH
- Potential of ezetimibe in memory deficits associated with dementia of alzheimer′s type in mice
- (2010) Nirmal Singh et al. INDIAN JOURNAL OF PHARMACOLOGY
- Treadmill training restores spatial cognitive deficits and neurochemical alterations in the hippocampus of rats submitted to an intracerebroventricular administration of streptozotocin
- (2010) Letícia Rodrigues et al. JOURNAL OF NEURAL TRANSMISSION
- Effects of Erythropoietin on Memory Deficits and Brain Oxidative Stress in the Mouse Models of Dementia
- (2010) Rohit Kumar et al. KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
- Involvement of PPAR-gamma in curcumin-mediated beneficial effects in experimental dementia
- (2010) Puneet Rinwa et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Oxidative stress in Alzheimer disease: A possibility for prevention
- (2010) David J. Bonda et al. NEUROPHARMACOLOGY
- Rosiglitazone Rescues Memory Impairment in Alzheimer's Transgenic Mice: Mechanisms Involving a Reduced Amyloid and Tau Pathology
- (2010) Luis Escribano et al. NEUROPSYCHOPHARMACOLOGY
- Organoselenium improves memory decline in mice: Involvement of acetylcholinesterase activity
- (2010) Simone Pinton et al. NEUROSCIENCE LETTERS
- Protective Effects of Intranasal Losartan in the APP/PS1 Transgenic Mouse Model of Alzheimer Disease
- (2010) Lusine Danielyan et al. REJUVENATION RESEARCH
- ‘Too much good news’ – are Alzheimer mouse models trying to tell us how to prevent, not cure, Alzheimer's disease?
- (2010) Kathleen R. Zahs et al. TRENDS IN NEUROSCIENCES
- Effects of Pycnogenol and vitamin E on cognitive deficits and oxidative damage induced by intracerebroventricular streptozotocin in rats
- (2009) Tauheed Ishrat et al. BEHAVIOURAL PHARMACOLOGY
- Selenium prevents cognitive decline and oxidative damage in rat model of streptozotocin-induced experimental dementia of Alzheimer's type
- (2009) Tauheed Ishrat et al. BRAIN RESEARCH
- Amelioration of intracerebroventricular streptozotocin induced cognitive dysfunction and oxidative stress by vinpocetine — a PDE1 inhibitor
- (2009) Rahul Deshmukh et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Amelioration of cognitive deficits and neurodegeneration by curcumin in rat model of sporadic dementia of Alzheimer's type (SDAT)☆
- (2009) Tauheed Ishrat et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Exploring mechanism of pioglitazone-induced memory restorative effect in experimental dementia
- (2009) Baljinder Kaur et al. FUNDAMENTAL & CLINICAL PHARMACOLOGY
- Lithium Trial in Alzheimer's Disease
- (2009) Harald Hampel et al. JOURNAL OF CLINICAL PSYCHIATRY
- Statins Reduce the Neurofibrillary Tangle Burden in a Mouse Model of Tauopathy
- (2009) Moran Boimel et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- -Amyloid Oligomers Induce Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate via c-Jun N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and Curcumin
- (2009) Q.-L. Ma et al. JOURNAL OF NEUROSCIENCE
- Effect of chronic treatment of carvedilol on oxidative stress in an intracerebroventricular streptozotocin induced model of dementia in rats
- (2009) Atish Kumar Prakash et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Protective effect of curcumin against intracerebral streptozotocin induced impairment in memory and cerebral blood flow
- (2009) Himani Awasthi et al. LIFE SCIENCES
- Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1ΔE9 mouse model of Alzheimer's disease
- (2009) E M Toledo et al. MOLECULAR PSYCHIATRY
- Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease
- (2009) Tomohiko Sato et al. NEUROBIOLOGY OF AGING
- Consumption of Grape Seed Extract Prevents Amyloid-β Deposition and Attenuates Inflammation in Brain of an Alzheimer’s Disease Mouse
- (2009) Yan-Jiang Wang et al. NEUROTOXICITY RESEARCH
- Effect of curcumin on brain insulin receptors and memory functions in STZ (ICV) induced dementia model of rat
- (2009) Rahul Agrawal et al. PHARMACOLOGICAL RESEARCH
- Chronic treatment with tocotrienol, an isoform of vitamin E, prevents intracerebroventricular streptozotocin-induced cognitive impairment and oxidative–nitrosative stress in rats
- (2009) Vinod Tiwari et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Melatonin alleviates memory deficits and neuronal degeneration induced by intracerebroventricular administration of streptozotocin in rats
- (2009) Gunjan Saxena et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Curcumin ameliorates impaired insulin/IGF signalling and memory deficit in a streptozotocin-treated rat model
- (2008) Ahmet Turan Isik et al. AGE
- Angiotensin Converting Enzyme Inhibitors and Cognitive and Functional Decline in Patients with Alzheimer's Disease: An Observational Study
- (2008) Ihab M. Hajjar et al. American Journal of Alzheimers Disease and Other Dementias
- Wheel-running in a transgenic mouse model of Alzheimer's disease: Protection or symptom?
- (2008) Helene Richter et al. BEHAVIOURAL BRAIN RESEARCH
- Candesartan improves memory decline in mice: Involvement of AT1 receptors in memory deficit induced by intracerebral streptozotocin
- (2008) Santoshkumar Tota et al. BEHAVIOURAL BRAIN RESEARCH
- Therapeutic potential of resveratrol in Alzheimer's disease
- (2008) Valérie Vingtdeux et al. BMC NEUROSCIENCE
- Study of neuroprotection of donepezil, a therapy for Alzheimer's disease
- (2008) S. Akasofu et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Complete Rescue of Cerebrovascular Function in Aged Alzheimer's Disease Transgenic Mice by Antioxidants and Pioglitazone, a Peroxisome Proliferator-Activated Receptor Agonist
- (2008) N. Nicolakakis et al. JOURNAL OF NEUROSCIENCE
- Modulation of celecoxib- and streptozotocin-induced experimental dementia of Alzheimer's disease by pitavastatin and donepezil
- (2008) Bhupesh Sharma et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial
- (2008) Clive Holmes et al. LANCET
- Effects of treadmill exercise on memory and c-Fos expression in the hippocampus of the rats with intracerebroventricular injection of streptozotocin
- (2008) Yong-Seok Jee et al. NEUROSCIENCE LETTERS
- Exploitation of HIV protease inhibitor Indinavir as a memory restorative agent in experimental dementia
- (2008) Bhupesh Sharma et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- New polyphenols active on β-amyloid aggregation
- (2007) Céline Rivière et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Effect of donepezil and tacrine on oxidative stress in intracerebral streptozotocin-induced model of dementia in mice
- (2007) Gunjan Saxena et al. EUROPEAN JOURNAL OF PHARMACOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search