Bispecific therapeutic aptamers for targeted therapy of cancer: a review on cellular perspective
出版年份 2018 全文链接
标题
Bispecific therapeutic aptamers for targeted therapy of cancer: a review on cellular perspective
作者
关键词
Aptamers, Bispecific aptamers, Aptamer chimera, Antitumor immunity, Multifunctional chimera, Multimodal nanomedicine
出版物
JOURNAL OF MOLECULAR MEDICINE-JMM
Volume 96, Issue 9, Pages 885-902
出版商
Springer Nature America, Inc
发表日期
2018-07-28
DOI
10.1007/s00109-018-1669-y
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Recent advances in aptamer-armed multimodal theranostic nanosystems for imaging and targeted therapy of cancer
- (2018) Somayeh Vandghanooni et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Aptamer–drug conjugate: targeted delivery of doxorubicin in a HER3 aptamer-functionalized liposomal delivery system reduces cardiotoxicity
- (2018) Xiao-qian Dou et al. International Journal of Nanomedicine
- STAT3 Gene Silencing by Aptamer-siRNA Chimera as Selective Therapeutic for Glioblastoma
- (2018) Carla Lucia Esposito et al. Molecular Therapy-Nucleic Acids
- Targeted Delivery of Auristatin-Modified Toxins to Pancreatic Cancer Using Aptamers
- (2018) Christina Kratschmer et al. Molecular Therapy-Nucleic Acids
- Aptamer Therapeutics in Cancer: Current and Future
- (2018) Yoshihiro Morita et al. Cancers
- Current Advances in Aptamers for Cancer Diagnosis and Therapy
- (2018) Shin-ichiro Hori et al. Cancers
- Recent Advances in SELEX Technology and Aptamer Applications in Biomedicine
- (2017) Zhenjian Zhuo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Aptamers and Glioblastoma: Their Potential Use for Imaging and Therapeutic Applications
- (2017) Emma Hays et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Anti-FGFR1 aptamer-tagged superparamagnetic conjugates for anticancer hyperthermia therapy
- (2017) Przemysław M Jurek et al. International Journal of Nanomedicine
- Aptamer-conjugated PEGylated quantum dots targeting epidermal growth factor receptor variant III for fluorescence imaging of glioma
- (2017) Jiaze Tang et al. International Journal of Nanomedicine
- Construction of DNAzyme-Encapsulated Fibermats Using the Precursor Network Polymer of Poly(γ-glutamate) and 4-Glycidyloxypropyltrimethoxysilane
- (2017) Koji Mizuno et al. LANGMUIR
- Olaptesed pegol, an anti-CXCL12/SDF-1 Spiegelmer, alone and with bortezomib–dexamethasone in relapsed/refractory multiple myeloma: a Phase IIa Study
- (2017) H Ludwig et al. LEUKEMIA
- PLGA nanoparticles with CD133 aptamers for targeted delivery and sustained release of propranolol to hemangioma
- (2017) Xiaonan Guo et al. Nanomedicine
- Self-Assembled Aptamer-Nanomedicine for Targeted Chemotherapy and Gene Therapy
- (2017) Nianxi Zhao et al. Small
- Simultaneous targeting of CD44 and EpCAM with a bispecific aptamer effectively inhibits intraperitoneal ovarian cancer growth
- (2017) Jingying Zheng et al. Theranostics
- Aptamer-Drug Conjugates of Active Metabolites of Nucleoside Analogs and Cytotoxic Agents Inhibit Pancreatic Tumor Cell Growth
- (2017) Sorah Yoon et al. Molecular Therapy-Nucleic Acids
- Current and Prospective Protein Biomarkers of Lung Cancer
- (2017) Tatiana Zamay et al. Cancers
- Long-term outcomes of responders in a randomized, controlled phase II trial of aptamer AS1411 in AML.
- (2017) D. Rizzieri et al. JOURNAL OF CLINICAL ONCOLOGY
- Tumor-Infiltrating Lymphocytes: A Promising Biomarker in Breast Cancer
- (2016) Barbara Ingold Heppner et al. Breast Care
- A specific aptamer-cell penetrating peptides complex delivered siRNA efficiently and suppressed prostate tumor growthin vivo
- (2016) Yanjun Diao et al. CANCER BIOLOGY & THERAPY
- Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy
- (2016) Hong-Min Meng et al. CHEMICAL SOCIETY REVIEWS
- Theranostic MUC-1 aptamer targeted gold coated superparamagnetic iron oxide nanoparticles for magnetic resonance imaging and photothermal therapy of colon cancer
- (2016) Morteza Azhdarzadeh et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Aptamer Functionalized Cisplatin-Albumin Nanoparticles for Targeted Delivery to Epidermal Growth Factor Receptor Positive Cervical Cancer
- (2016) Yao Chen et al. Journal of Biomedical Nanotechnology
- Enhancement of Thermal Damage to Adenocarcinoma Cells by Iron Nanoparticles Modified with MUC1 Aptamer
- (2016) Fangqin Guo et al. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
- Advances in the development of aptamer drug conjugates for targeted drug delivery
- (2016) Ke Chen et al. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
- Improved Synthesis andIn VitroEvaluation of an Aptamer Ribosomal Toxin Conjugate
- (2016) Linsley Kelly et al. Nucleic Acid Therapeutics
- MRP1-CD28 bi-specific oligonucleotide aptamers: target costimulation to drug-resistant melanoma cancer stem cells
- (2016) Mario Martínez Soldevilla et al. Oncotarget
- Aptamer-miRNA-212 Conjugate Sensitizes NSCLC Cells to TRAIL
- (2016) Margherita Iaboni et al. Molecular Therapy-Nucleic Acids
- DNA-Hybrid-Gated Photothermal Mesoporous Silica Nanoparticles for NIR-Responsive and Aptamer-Targeted Drug Delivery
- (2015) Yuanxin Zhang et al. ACS Applied Materials & Interfaces
- Oligonucleotide aptamer-drug conjugates for targeted therapy of acute myeloid leukemia
- (2015) Nianxi Zhao et al. BIOMATERIALS
- Chimeric nucleolin aptamer with survivin DNAzyme for cancer cell targeted delivery
- (2015) Nithya Subramanian et al. CHEMICAL COMMUNICATIONS
- Prognostic and predictive value of tumor-infiltrating lymphocytes in breast cancer: a systematic review and meta-analysis
- (2015) X. Yu et al. Clinical & Translational Oncology
- Cellular delivery of shRNA using aptamer-conjugated PLL-alkyl-PEI nanoparticles
- (2015) Saeedeh Askarian et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Antibody-mediated delivery of therapeutics for cancer therapy
- (2015) Sagun Parakh et al. Expert Opinion on Drug Delivery
- An AS1411 aptamer-conjugated liposomal system containing a bubble-generating agent for tumor-specific chemotherapy that overcomes multidrug resistance
- (2015) Zi-Xian Liao et al. JOURNAL OF CONTROLLED RELEASE
- Methotrexate-conjugated quantum dots: synthesis, characterisation and cytotoxicity in drug resistant cancer cells
- (2015) Mohammad Johari-Ahar et al. JOURNAL OF DRUG TARGETING
- A unique aptamer-drug conjugate for targeted therapy of multiple myeloma
- (2015) J Wen et al. LEUKEMIA
- Systemic Administration and Targeted Radiosensitization via Chemically Synthetic Aptamer-siRNA Chimeras in Human Tumor Xenografts
- (2015) X. Ni et al. MOLECULAR CANCER THERAPEUTICS
- An aptamer-targeting photoresponsive drug delivery system using “off–on” graphene oxide wrapped mesoporous silica nanoparticles
- (2015) Yuxia Tang et al. Nanoscale
- Formulation, characterization, and geno/cytotoxicity studies of galbanic acid-loaded solid lipid nanoparticles
- (2015) Morteza Eskandani et al. PHARMACEUTICAL BIOLOGY
- Locked nucleic acid modified bi-specific aptamer-targeted nanoparticles carrying survivin antagonist towards effective colon cancer therapy
- (2015) Kislay Roy et al. RSC Advances
- Multifunctional mitoxantrone-conjugated magnetic nanosystem for targeted therapy of folate receptor-overexpressing malignant cells
- (2015) Jaleh Barar et al. JOURNAL OF NANOBIOTECHNOLOGY
- In Situ immunization by bispecific antibody targeted T cell therapy in breast cancer
- (2015) Archana Thakur et al. OncoImmunology
- EpCAM Aptamer-siRNA Chimera Targets and Regress Epithelial Cancer
- (2015) Nithya Subramanian et al. PLoS One
- A Novel Bispecific Antibody against Human CD3 and Ephrin Receptor A10 for Breast Cancer Therapy
- (2015) Shintaro Taki et al. PLoS One
- In vitro and in vivo Evaluation of Antitumor Drug-Loaded Aptamer Targeted Single-Walled Carbon Nanotubes System
- (2014) Huijuan Zhang et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- Self-reporter shikonin-Act-loaded solid lipid nanoparticle: Formulation, physicochemical characterization and geno/cytotoxicity evaluation
- (2014) Morteza Eskandani et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Deregulation of cell signaling in cancer
- (2014) Filippo G. Giancotti FEBS LETTERS
- Protein-tyrosine Pseudokinase 7 (PTK7) Directs Cancer Cell Motility and Metastasis
- (2014) Vladislav S. Golubkov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Gold nanoparticle–DNA aptamer composites as a universal carrier for in vivo delivery of biologically functional proteins
- (2014) Sang-Mi Ryou et al. JOURNAL OF CONTROLLED RELEASE
- RNA aptamer-conjugated liposome as an efficient anticancer drug delivery vehicle targeting cancer cells in vivo
- (2014) Si Eun Baek et al. JOURNAL OF CONTROLLED RELEASE
- Multifunctional Aptamer-miRNA Conjugates for Targeted Cancer Therapy
- (2014) Carla L Esposito et al. MOLECULAR THERAPY
- PTK 7 Is a Transforming Gene and Prognostic Marker for Breast Cancer and Nodal Metastasis Involvement
- (2014) Silvia Gärtner et al. PLoS One
- Targeted Disruption of β-Arrestin 2-Mediated Signaling Pathways by Aptamer Chimeras Leads to Inhibition of Leukemic Cell Growth
- (2014) Jonathan W. Kotula et al. PLoS One
- Targeting 4-1BB Costimulation to the Tumor Stroma with Bispecific Aptamer Conjugates Enhances the Therapeutic Index of Tumor Immunotherapy
- (2014) B. Schrand et al. Cancer Immunology Research
- Cell-type-specific, Aptamer-functionalized Agents for Targeted Disease Therapy
- (2014) Jiehua Zhou et al. Molecular Therapy-Nucleic Acids
- Specific Capture and Release of Circulating Tumor Cells Using Aptamer-Modified Nanosubstrates
- (2013) Qinglin Shen et al. ADVANCED MATERIALS
- A polyvalent aptamer system for targeted drug delivery
- (2013) Zhiqing Zhang et al. BIOMATERIALS
- Aptamer-conjugated and doxorubicin-loaded unimolecular micelles for targeted therapy of prostate cancer
- (2013) Wenjin Xu et al. BIOMATERIALS
- Use of Oligonucleotide Aptamer Ligands to Modulate the Function of Immune Receptors
- (2013) E. Gilboa et al. CLINICAL CANCER RESEARCH
- Tamoxifen loaded folic acid armed PEGylated magnetic nanoparticles for targeted imaging and therapy of cancer
- (2013) Mostafa Heidari Majd et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- DNAzyme Delivery Approaches in Biological Settings
- (2013) Cecilia Chan et al. CURRENT MEDICINAL CHEMISTRY
- Specific targeting of cancer cells by multifunctional mitoxantrone-conjugated magnetic nanoparticles
- (2013) Mostafa Heidari Majd et al. JOURNAL OF DRUG TARGETING
- Solubilization of flurbiprofen into aptamer-modified PEG–PLA micelles for targeted delivery to brain-derived endothelial cellsin vitro
- (2013) Chaofeng Mu et al. JOURNAL OF MICROENCAPSULATION
- Durable Knockdown and Protection From HIV Transmission in Humanized Mice Treated With Gel-formulated CD4 Aptamer-siRNA Chimeras
- (2013) Lee Adam Wheeler et al. MOLECULAR THERAPY
- ARC15105 Is a Potent Antagonist of Von Willebrand Factor Mediated Platelet Activation and Adhesion
- (2012) Jolanta M. Siller-Matula et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Whole-cell SELEX aptamer-functionalised poly(ethyleneglycol)-poly(ε-caprolactone) nanoparticles for enhanced targeted glioblastoma therapy
- (2012) Huile Gao et al. BIOMATERIALS
- AS1411 aptamer tagged PLGA-lecithin-PEG nanoparticles for tumor cell targeting and drug delivery
- (2012) Athulya Aravind et al. BIOTECHNOLOGY AND BIOENGINEERING
- Reversal of Paclitaxel Resistance in Epithelial Ovarian Carcinoma Cells by a MUC1 Aptamer-let-7i Chimera
- (2012) Nenghui Liu et al. CANCER INVESTIGATION
- Self-Assembled Aptamer-Based Drug Carriers for Bispecific Cytotoxicity to Cancer Cells
- (2012) Guizhi Zhu et al. Chemistry-An Asian Journal
- Use of DNAzymes for cancer research and therapy
- (2012) ZhiJie Xu et al. CHINESE SCIENCE BULLETIN
- Structuring Polymers for Delivery of DNA-Based Therapeutics: Updated Insights
- (2012) Madhu Gupta et al. CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS
- Anticancer role of MUC1 aptamer–miR-29b chimera in epithelial ovarian carcinoma cells through regulation of PTEN methylation
- (2012) Furong Dai et al. Targeted Oncology
- Release of Photoactivatable Drugs from Plasmonic Nanoparticles for Targeted Cancer Therapy
- (2011) Yun-Ling Luo et al. ACS Nano
- Aptamer-conjugated nanomaterials and their applications
- (2011) Liu Yang et al. ADVANCED DRUG DELIVERY REVIEWS
- Chimeric aptamers in cancer cell-targeted drug delivery
- (2011) Jagat R. Kanwar et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Aptamers Against Cell Surface Receptors: Selection, Modification and Application
- (2011) J. Wang et al. CURRENT MEDICINAL CHEMISTRY
- Tumor-Targeted Drug Delivery with Aptamers
- (2011) Y. Zhang et al. CURRENT MEDICINAL CHEMISTRY
- Bi-specific Aptamers Mediating Tumor Cell Lysis
- (2011) Achim Boltz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts
- (2011) Xiaohua Ni et al. JOURNAL OF CLINICAL INVESTIGATION
- Tumor targeted quantum dot-mucin 1 aptamer-doxorubicin conjugate for imaging and treatment of cancer
- (2011) Ronak Savla et al. JOURNAL OF CONTROLLED RELEASE
- Targeted drug delivery to tumors: Myths, reality and possibility
- (2011) You Han Bae et al. JOURNAL OF CONTROLLED RELEASE
- Targeting 4-1BB Costimulation to Disseminated Tumor Lesions With Bi-specific Oligonucleotide Aptamers
- (2011) Fernando Pastor et al. MOLECULAR THERAPY
- Targeted Cell-Cell Interactions by DNA Nanoscaffold-Templated Multivalent Bispecific Aptamers
- (2011) Xiaowei Liu et al. Small
- A nanocomplex that is both tumor cell-selective and cancer gene-specific for anaplastic large cell lymphoma
- (2011) Nianxi Zhao et al. JOURNAL OF NANOBIOTECHNOLOGY
- An Aptamer Targeting the Apical-Loop Domain Modulates pri-miRNA Processing
- (2010) Christina E. Lünse et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Reversible Targeting and controlled release delivery of daunorubicin to cancer cells by aptamer-wrapped carbon nanotubes
- (2010) Seyed Mohammad Taghdisi et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Wnt signal transduction pathways
- (2010) Yuko Komiya et al. Organogenesis
- Molecular Assembly of an Aptamer-Drug Conjugate for Targeted Drug Delivery to Tumor Cells
- (2009) Yu-Fen Huang et al. CHEMBIOCHEM
- A liposome-based nanostructure for aptamer directed delivery
- (2009) Huaizhi Kang et al. CHEMICAL COMMUNICATIONS
- Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
- (2009) Bryan T. MacDonald et al. DEVELOPMENTAL CELL
- Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer
- (2009) Paula J. Bates et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Nanoparticle-based targeted drug delivery
- (2009) Rajesh Singh et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- DNAzyme Delivery Systems: Getting Past First Base
- (2009) Mei Lin Tan et al. Expert Opinion on Drug Delivery
- An efficient cell-targeting and intracellular controlled-release drug delivery system based on MSN-PEM-aptamer conjugates
- (2009) Chun-Ling Zhu et al. JOURNAL OF MATERIALS CHEMISTRY
- Aptamer-conjugated dendrimer-modified quantum dots for cancer cell targeting and imaging
- (2009) Zhiming Li et al. MATERIALS LETTERS
- Plasma Membrane Nucleolin Is a Receptor for the Anticancer Aptamer AS1411 in MV4-11 Leukemia Cells
- (2009) S. Soundararajan et al. MOLECULAR PHARMACOLOGY
- The promises and pitfalls of RNA-interference-based therapeutics
- (2009) Daniela Castanotto et al. NATURE
- Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors
- (2009) Justin P Dassie et al. NATURE BIOTECHNOLOGY
- Active targeting schemes for nanoparticle systems in cancer therapeutics
- (2008) James D. Byrne et al. ADVANCED DRUG DELIVERY REVIEWS
- The Nucleolin Targeting Aptamer AS1411 Destabilizes Bcl-2 Messenger RNA in Human Breast Cancer Cells
- (2008) S. Soundararajan et al. CANCER RESEARCH
- MicroRNA-21 Targets a Network of Key Tumor-Suppressive Pathways in Glioblastoma Cells
- (2008) T. Papagiannakopoulos et al. CANCER RESEARCH
- Superparamagnetic Iron Oxide Nanoparticle-Aptamer Bioconjugates for Combined Prostate Cancer Imaging and Therapy
- (2008) Andrew Z. Wang et al. ChemMedChem
- Cell-Specific Induction of Apoptosis by Rationally Designed Bivalent Aptamer-siRNA Transcripts Silencing Eukaryotic Elongation Factor 2
- (2008) Ulrich Wullner et al. CURRENT CANCER DRUG TARGETS
- Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice
- (2008) James O. McNamara et al. JOURNAL OF CLINICAL INVESTIGATION
- Cell-Specific Aptamer Probes for Membrane Protein Elucidation in Cancer Cells
- (2008) Dihua Shangguan et al. JOURNAL OF PROTEOME RESEARCH
- Toward Reliable Gold Nanoparticle Patterning On Self-Assembled DNA Nanoscaffold
- (2008) Jaswinder Sharma et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Assembling Materials with DNA as the Guide
- (2008) F. A. Aldaye et al. SCIENCE
- Cell-Specific Internalization Study of an Aptamer from Whole Cell Selection
- (2007) Zeyu Xiao et al. CHEMISTRY-A EUROPEAN JOURNAL
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