Chimeric nucleolin aptamer with survivin DNAzyme for cancer cell targeted delivery

Nucleolin-targeting liposomes guided by aptamer AS1411 for the delivery of siRNA for the treatment of malignant melanomas

(2014) Liyu Li et al.   BIOMATERIALS

Dysregulation of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in advanced retinoblastoma

(2014) Job Sudhakar et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Cell-surface nucleolin acts as a central mediator for carcinogenic, anti-carcinogenic, and disease-related ligands

(2014) Hirota Fujiki et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Survivin mRNA-circulating tumor cells predict treatment efficacy of chemotherapy and survival for advanced non-small cell lung cancer patients

(2014) Yong-Jie Du et al.   TUMOR BIOLOGY

Oligonucleotide Aptamers: New Tools for Targeted Cancer Therapy

(2014) Hongguang Sun et al.   Molecular Therapy-Nucleic Acids

Ani-survivin DNAzymes Inhibit Cell Proliferation and Migration in Breast Cancer Cell Line MCF-7

(2013) Min Zhang et al.   Asian Pacific Journal of Cancer Prevention

AKT1 Inhibitory DNAzymes Inhibit Cell Proliferation and Migration of Thyroid Cancer Cells

(2013) Le Yang et al.   Asian Pacific Journal of Cancer Prevention

Treat cancers by targeting survivin: Just a dream or future reality?

(2013) Mohane Selvaraj Coumar et al.   CANCER TREATMENT REVIEWS

An improved G-quadruplex DNAzyme for dual-functional electrochemical biosensing of adenosines and hydrogen peroxide from cancer cells

(2013) Zong-Hua Wang et al.   CHEMICAL COMMUNICATIONS

Cleavage of BCR–ABL transcripts at the T315I point mutation by DNAzyme promotes apoptotic cell death in imatinib-resistant BCR–ABL leukemic cells

(2013) J E Kim et al.   LEUKEMIA

Hypoxic tumor microenvironment in advanced retinoblastoma

(2013) Job Sudhakar et al.   PEDIATRIC BLOOD & CANCER

Multifunctional AS1411-functionalized fluorescent gold nanoparticles for targeted cancer cell imaging and efficient photodynamic therapy

(2013) Jun Ai et al.   TALANTA

Use of DNAzymes for cancer research and therapy

(2012) ZhiJie Xu et al.   CHINESE SCIENCE BULLETIN

Retinoblastoma

(2012) Helen Dimaras et al.   LANCET

Survivin Signaling in Clinical Oncology: A Multifaceted Dragon

(2012) Jagat R. Kanwar et al.   MEDICINAL RESEARCH REVIEWS

Aptamer-DNAzyme hairpins for biosensing of Ochratoxin A

(2011) Cheng Yang et al.   BIOSENSORS & BIOELECTRONICS

Chimeric aptamers in cancer cell-targeted drug delivery

(2011) Jagat R. Kanwar et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Targeting survivin in cancer: patent review

(2010) Jagat R Kanwar et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Oligodeoxyribozymes That Cleave  -Catenin Messenger RNA Inhibit Growth of Colon Cancer Cells via Reduction of  -Catenin Response Transcription

(2010) B.-R. Choi et al.   MOLECULAR CANCER THERAPEUTICS

Detection of survivin protein in aqueous humor and serum of retinoblastoma patients and its clinical significance

(2009) Hanan H. Shehata et al.   CLINICAL BIOCHEMISTRY

Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer

(2009) Paula J. Bates et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

The Nucleolin Targeting Aptamer AS1411 Destabilizes Bcl-2 Messenger RNA in Human Breast Cancer Cells

(2008) S. Soundararajan et al.   CANCER RESEARCH

Dz13, a DNAzyme Targeting c-jun, Induces Off-Target Cytotoxicity in Endothelial Cells with Features of Nonapoptotic Programmed Cell Death

(2008) Mary Margaret Gozar et al.   OLIGONUCLEOTIDES