Targeting MET and AXL overcomes resistance to sunitinib therapy in renal cell carcinoma
出版年份 2015 全文链接
标题
Targeting MET and AXL overcomes resistance to sunitinib therapy in renal cell carcinoma
作者
关键词
-
出版物
ONCOGENE
Volume 35, Issue 21, Pages 2687-2697
出版商
Springer Nature
发表日期
2015-09-14
DOI
10.1038/onc.2015.343
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A phase I study of cabozantinib (XL184) in patients with renal cell cancer
- (2014) T. K. Choueiri et al. ANNALS OF ONCOLOGY
- Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET
- (2014) Erinn B. Rankin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting the Hepatocyte Growth Factor/c-Met Signaling Pathway in Renal Cell Carcinoma
- (2013) Lauren C. Harshman et al. CANCER JOURNAL
- Emerging antiangiogenics for renal cancer
- (2013) Charlotte Domblides et al. EXPERT OPINION ON EMERGING DRUGS
- Preclinical validation of AXL receptor as a target for antibody-based pancreatic cancer immunotherapy
- (2013) W Leconet et al. ONCOGENE
- In Vitro and In Vivo Activity of Cabozantinib (XL184), an Inhibitor of RET, MET, and VEGFR2, in a Model of Medullary Thyroid Cancer
- (2013) Frauke Bentzien et al. THYROID
- c-Met is a prognostic marker and potential therapeutic target in clear cell renal cell carcinoma
- (2012) G. T. Gibney et al. ANNALS OF ONCOLOGY
- Rapid Angiogenesis Onset after Discontinuation of Sunitinib Treatment of Renal Cell Carcinoma Patients
- (2012) A. W. Griffioen et al. CLINICAL CANCER RESEARCH
- Axl is essential for VEGF-A-dependent activation of PI3K/Akt
- (2012) Guo-Xiang Ruan et al. EMBO JOURNAL
- Cabozantinib in Patients With Advanced Prostate Cancer: Results of a Phase II Randomized Discontinuation Trial
- (2012) David C. Smith et al. JOURNAL OF CLINICAL ONCOLOGY
- TNF- Induces Epithelial-Mesenchymal Transition of Renal Cell Carcinoma Cells via a GSK3 -Dependent Mechanism
- (2012) M.-Y. Ho et al. MOLECULAR CANCER RESEARCH
- Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair
- (2012) Xue Zhang et al. NATURE GENETICS
- MET: a promising anticancer therapeutic target
- (2012) Solange Peters et al. Nature Reviews Clinical Oncology
- Profiling phospho-signaling networks in breast cancer using reverse-phase protein arrays
- (2012) T S Gujral et al. ONCOGENE
- Suppression of Tumor Invasion and Metastasis by Concurrent Inhibition of c-Met and VEGF Signaling in Pancreatic Neuroendocrine Tumors
- (2012) Barbara Sennino et al. Cancer Discovery
- Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
- (2011) Peter Friedl et al. CELL
- Hepatocyte growth factor-induced c-Src-phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway inhibits dendritic cell activation by blocking IκB kinase activity
- (2011) Eshu Singhal et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- EGFR and MET receptor tyrosine kinase–altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers
- (2011) Michela Garofalo et al. NATURE MEDICINE
- Gene and protein expression markers of response to combined antiangiogenic and epidermal growth factor targeted therapy in renal cell carcinoma
- (2010) D. Tsavachidou-Fenner et al. ANNALS OF ONCOLOGY
- Interleukin-8 Mediates Resistance to Antiangiogenic Agent Sunitinib in Renal Cell Carcinoma
- (2010) D. Huang et al. CANCER RESEARCH
- AXL Is an Essential Factor and Therapeutic Target for Metastatic Ovarian Cancer
- (2010) E. B. Rankin et al. CANCER RESEARCH
- Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors
- (2010) Rachel MA Linger et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies
- (2010) X Ye et al. ONCOGENE
- Myelosuppression and kinase selectivity of multikinase angiogenesis inhibitors
- (2009) R Kumar et al. BRITISH JOURNAL OF CANCER
- Patterns of disease progression in metastatic renal cell carcinoma patients treated with antivascular agents and interferon
- (2009) Elizabeth R. Plimack et al. CANCER
- Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
- (2009) Marta Pàez-Ribes et al. CANCER CELL
- Differential Expression of Axl and Gas6 in Renal Cell Carcinoma Reflecting Tumor Advancement and Survival
- (2009) A. Gustafsson et al. CLINICAL CANCER RESEARCH
- Cytoplasmic ACK1 Interaction with Multiple Receptor Tyrosine Kinases Is Mediated by Grb2
- (2009) Lin Pao-Chun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phase II Presurgical Feasibility Study of Bevacizumab in Untreated Patients With Metastatic Renal Cell Carcinoma
- (2009) Eric Jonasch et al. JOURNAL OF CLINICAL ONCOLOGY
- Gas6 and the Receptor Tyrosine Kinase Axl in Clear Cell Renal Cell Carcinoma
- (2009) Anna Gustafsson et al. PLoS One
- Cytoplasmic Sequestration of p27 via AKT Phosphorylation in Renal Cell Carcinoma
- (2008) J. Kim et al. CLINICAL CANCER RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started