Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors
出版年份 2010 全文链接
标题
Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors
作者
关键词
-
出版物
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 14, Issue 10, Pages 1073-1090
出版商
Informa Healthcare
发表日期
2010-09-02
DOI
10.1517/14728222.2010.515980
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- (2010) E. G. Van Meir et al. CA-A CANCER JOURNAL FOR CLINICIANS
- The Axl receptor tyrosine kinase confers an adverse prognostic influence in pancreatic cancer and represents a new therapeutic target
- (2010) Jan-Bart M. Koorstra et al. CANCER BIOLOGY & THERAPY
- Receptor Tyrosine Kinase Coactivation Networks in Cancer
- (2010) A. M. Xu et al. CANCER RESEARCH
- R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
- (2010) S. J. Holland et al. CANCER RESEARCH
- A Phase I Study of Foretinib, a Multi-Targeted Inhibitor of c-Met and Vascular Endothelial Growth Factor Receptor 2
- (2010) J. P. Eder et al. CLINICAL CANCER RESEARCH
- Comprehensive Mapping of the Human Kinome to Epidermal Growth Factor Receptor Signaling
- (2010) Kakajan Komurov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Review of Oncology and Hematology Drug Product Approvals at the US Food and Drug Administration Between July 2005 and December 2007
- (2010) R. Sridhara et al. JNCI-Journal of the National Cancer Institute
- Myeloid Zinc Finger 1 Induces Migration, Invasion, and In vivo Metastasis through Axl Gene Expression in Solid Cancer
- (2010) G. Mudduluru et al. MOLECULAR CANCER RESEARCH
- Inhibition of Mer and Axl Receptor Tyrosine Kinases in Astrocytoma Cells Leads to Increased Apoptosis and Improved Chemosensitivity
- (2010) A. K. Keating et al. MOLECULAR CANCER THERAPEUTICS
- Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases
- (2010) Y Liu et al. ONCOGENE
- Triple-negative breast cancer--current status and future directions
- (2009) O. Gluz et al. ANNALS OF ONCOLOGY
- Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6
- (2009) S. Loges et al. BLOOD
- Mer receptor tyrosine kinase is a novel therapeutic target in pediatric B-cell acute lymphoblastic leukemia
- (2009) R. M. A. Linger et al. BLOOD
- MP470, a novel receptor tyrosine kinase inhibitor, in combination with Erlotinib inhibits the HER family/PI3K/Akt pathway and tumor growth in prostate cancer
- (2009) Wenqing Qi et al. BMC CANCER
- DNA Copy Number Variation and Gene Expression Analyses Reveal the Implication of Specific Oncogenes and Genes in GBM
- (2009) Javier Margareto et al. CANCER INVESTIGATION
- Novel Mechanism of Lapatinib Resistance in HER2-Positive Breast Tumor Cells: Activation of AXL
- (2009) L. Liu et al. CANCER RESEARCH
- Differential Expression of Axl and Gas6 in Renal Cell Carcinoma Reflecting Tumor Advancement and Survival
- (2009) A. Gustafsson et al. CLINICAL CANCER RESEARCH
- TAM receptors and the regulation of erythropoiesis in mice
- (2009) H. Tang et al. HAEMATOLOGICA
- Cytoplasmic ACK1 Interaction with Multiple Receptor Tyrosine Kinases Is Mediated by Grb2
- (2009) Lin Pao-Chun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mer tyrosine kinase (MerTK) promotes macrophage survival following exposure to oxidative stress
- (2009) Adil Anwar et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Discovery ofN-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a Selective and Orally Efficacious Inhibitor of the Met Kinase Superfamily
- (2009) Gretchen M. Schroeder et al. JOURNAL OF MEDICINAL CHEMISTRY
- Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
- (2009) Roger Stupp et al. LANCET ONCOLOGY
- Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial
- (2009) Tetsuya Mitsudomi et al. LANCET ONCOLOGY
- Gene expression profiling of imatinib and PD166326-resistant CML cell lines identifies Fyn as a gene associated with resistance to BCR-ABL inhibitors
- (2009) S. Grosso et al. MOLECULAR CANCER THERAPEUTICS
- Imatinib and beyond—exploring the full potential of targeted therapy for CML
- (2009) Alfonso Quintás-Cardama et al. Nature Reviews Clinical Oncology
- Kinase mutations in human disease: interpreting genotype–phenotype relationships
- (2009) Piya Lahiry et al. NATURE REVIEWS GENETICS
- Screening for Epidermal Growth Factor Receptor Mutations in Lung Cancer
- (2009) Rafael Rosell et al. NEW ENGLAND JOURNAL OF MEDICINE
- Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma
- (2009) Tony S. Mok et al. NEW ENGLAND JOURNAL OF MEDICINE
- Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis
- (2009) Y Li et al. ONCOGENE
- Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival
- (2009) C. Gjerdrum et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Growth arrest-specific gene 6 expression in human breast cancer
- (2008) O Mc Cormack et al. BRITISH JOURNAL OF CANCER
- Receptor tyrosine kinase AXL is induced by chemotherapy drugs and overexpression of AXL confers drug resistance in acute myeloid leukemia
- (2008) Chih-Chen Hong et al. CANCER LETTERS
- AXL Is a Potential Target for Therapeutic Intervention in Breast Cancer Progression
- (2008) Y.-X. Zhang et al. CANCER RESEARCH
- Axl and Growth Arrest Specific Gene 6 Are Frequently Overexpressed in Human Gliomas and Predict Poor Prognosis in Patients with Glioblastoma Multiforme
- (2008) M. Hutterer et al. CLINICAL CANCER RESEARCH
- Activity of Bosutinib, Dasatinib, and Nilotinib Against 18 Imatinib-Resistant BCR/ABL Mutants
- (2008) Sara Redaelli et al. JOURNAL OF CLINICAL ONCOLOGY
- Structural insights into the inhibited states of the Mer receptor tyrosine kinase
- (2008) Xudong Huang et al. JOURNAL OF STRUCTURAL BIOLOGY
- EGFR Inhibitors as First-Line Therapy in Advanced Non-small Cell Lung Cancer
- (2008) Thomas Fong et al. Journal of Thoracic Oncology
- Endogenous human microRNAs that suppress breast cancer metastasis
- (2008) Sohail F. Tavazoie et al. NATURE
- Axl promotes cell invasion by inducing MMP-9 activity through activation of NF-κB and Brg-1
- (2008) K-Y Tai et al. ONCOGENE
- Drug Insight: gastrointestinal stromal tumors (GIST)—the solid tumor model for cancer-specific treatment
- (2008) Stefan Sleijfer et al. Nature clinical practice. Oncology
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