Profiling phospho-signaling networks in breast cancer using reverse-phase protein arrays

Discovery of Small Molecule c-Met Inhibitors: Evolution and Profiles of Clinical Candidates

(2012) Ted Underiner et al.   Anti-Cancer Agents in Medicinal Chemistry

A Dual Array-Based Approach to Assess the Abundance and Posttranslational Modification State of Signaling Proteins

(2012) K. Luckert et al.   Science Signaling

Transcriptional activation of the Axl and PDGFR-α by c-Met through a ras- and Src-independent mechanism in human bladder cancer

(2011) Chen-Yun Yeh et al.   BMC CANCER

Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA

(2011) Mark Mackiewicz et al.   BREAST CANCER RESEARCH AND TREATMENT

Principles and Strategies for Developing Network Models in Cancer

(2011) Dana Pe'er et al.   CELL

Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks

(2011) Yu Kataoka et al.   INVESTIGATIONAL NEW DRUGS

Lysate Microarrays Enable High-throughput, Quantitative Investigations of Cellular Signaling

(2011) Mark Sevecka et al.   MOLECULAR & CELLULAR PROTEOMICS

Breast Cancer-Derived Bone Metastasis Can Be Effectively Reduced through Specific c-MET Inhibitor Tivantinib (ARQ 197) and shRNA c-MET Knockdown

(2011) S. Previdi et al.   MOLECULAR CANCER THERAPEUTICS

Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM

(2010) Charles J. Vaske et al.   BIOINFORMATICS

Pathway Analysis of Breast Cancer Genome-Wide Association Study Highlights Three Pathways and One Canonical Signaling Cascade

(2010) Idan Menashe et al.   CANCER RESEARCH

R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer

(2010) S. J. Holland et al.   CANCER RESEARCH

Functional Proteomic Analysis of Advanced Serous Ovarian Cancer Using Reverse Phase Protein Array: TGF-  Pathway Signaling Indicates Response to Primary Chemotherapy

(2010) M. S. Carey et al.   CLINICAL CANCER RESEARCH

Proteomic Profiling Identifies Pathways Dysregulated in Non-small Cell Lung Cancer and an Inverse Association of AMPK and Adhesion Pathways with Recurrence

(2010) Meera Nanjundan et al.   Journal of Thoracic Oncology

Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer

(2010) K Vuoriluoto et al.   ONCOGENE

A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers

(2010) Bryan T. Hennessy et al.   Clinical Proteomics

Evidence that Fold-Change, and Not Absolute Level, of β-Catenin Dictates Wnt Signaling

(2009) Lea Goentoro et al.   MOLECULAR CELL

Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival

(2009) C. Gjerdrum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AXL Is a Potential Target for Therapeutic Intervention in Breast Cancer Progression

(2008) Y.-X. Zhang et al.   CANCER RESEARCH

Cytokine-Induced Signaling Networks Prioritize Dynamic Range over Signal Strength

(2008) Kevin A. Janes et al.   CELL