Next-Generation Antithrombotics in Ischemic Stroke: Preclinical Perspective on ‘Bleeding-Free Antithrombosis’

Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain

(2012) Douglas J. Cook et al.   NATURE

GPIIb/IIIa inhibitors: From bench to bedside and back to bench again

(2012) Paul C. Armstrong et al.   THROMBOSIS AND HAEMOSTASIS

Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes

(2011) J. W. Rowley et al.   BLOOD

Platelets at work in primary hemostasis

(2011) Katleen Broos et al.   BLOOD REVIEWS

Blood coagulation factor XII—a neglected player in stroke pathophysiology

(2011) Mirko Pham et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Ischaemic stroke: a thrombo-inflammatory disease?

(2011) Bernhard Nieswandt et al.   JOURNAL OF PHYSIOLOGY-LONDON

Terutroban versus aspirin in patients with cerebral ischaemic events (PERFORM): a randomised, double-blind, parallel-group trial

(2011) Marie-Germaine Bousser et al.   LANCET

Arterial thrombosis—insidious, unpredictable and deadly

(2011) Shaun P Jackson   NATURE MEDICINE

Akuter ischämischer Schlaganfall

(2011) P. Kraft et al.   NERVENARZT

Sustained Reperfusion after Blockade of Glycoprotein-Receptor-Ib in Focal Cerebral Ischemia: An MRI Study at 17.6 Tesla

(2011) Mirko Pham et al.   PLoS One

Safety of Tirofiban in Acute Ischemic Stroke

(2011) Mario Siebler et al.   STROKE

von Willebrand Factor

(2011) Simon F. De Meyer et al.   STROKE

Combating innate inflammation: a new paradigm for acute treatment of stroke?

(2010) Guido Stoll et al.   Annals of the New York Academy of Sciences

Binding of von Willebrand Factor to Collagen and Glycoprotein Ibα, But Not to Glycoprotein IIb/IIIa, Contributes to Ischemic Stroke in Mice—Brief Report

(2010) Simon F. De Meyer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Variation in the von Willebrand factor gene is associated with von Willebrand factor levels and with the risk for cardiovascular disease

(2010) M. C. van Schie et al.   BLOOD

Effect of Intravenous Tirofiban and Aspirin in Reducing Short-Term and Long-Term Neurologic Deficit in Patients with Ischemic Stroke: A Double-Blind Randomized Trial

(2010) G. Torgano et al.   CEREBROVASCULAR DISEASES

Factor XIIa Inhibitor Recombinant Human Albumin Infestin-4 Abolishes Occlusive Arterial Thrombus Formation Without Affecting Bleeding

(2010) Ina Hagedorn et al.   CIRCULATION

Intrinsic Coagulation Activation and the Risk of Arterial Thrombosis in Young Women

(2010) B. Siegerink et al.   CIRCULATION

Stroke in a young patient treated by alteplase heralding an acquired thrombotic thrombocytopenic purpura

(2010) Amandine Sevy et al.   JOURNAL OF CLINICAL APHERESIS

Platelet receptor signaling in thrombus formation

(2010) David Stegner et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials

(2010) Kennedy R Lees et al.   LANCET

Antithrombotic drugs for patients with ischaemic stroke and transient ischaemic attack to prevent recurrent major vascular events

(2010) Graeme J Hankey et al.   LANCET NEUROLOGY

Cilostazol for prevention of secondary stroke (CSPS 2): an aspirin-controlled, double-blind, randomised non-inferiority trial

(2010) Yukito Shinohara et al.   LANCET NEUROLOGY

Far from the Heart: Counteracting coagulation

(2010) Charles T Esmon   NATURE MEDICINE

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired  IIb 3 Integrin Activation and Shear-Dependent Thrombus Formation in Mice Lacking Phospholipase D1

(2010) M. Elvers et al.   Science Signaling

High von Willebrand Factor Levels Increase the Risk of Stroke

(2010) Renske G. Wieberdink et al.   STROKE

Soluble Glycoprotein VI Is Raised in the Plasma of Patients With Acute Ischemic Stroke

(2010) Mohammad Al-Tamimi et al.   STROKE

von Willebrand factor-cleaving protease ADAMTS13 reduces ischemic brain injury in experimental stroke

(2009) B.-Q. Zhao et al.   BLOOD

Deficiency of von Willebrand factor protects mice from ischemic stroke

(2009) C. Kleinschnitz et al.   BLOOD

von Willebrand factor to the rescue

(2009) S. F. De Meyer et al.   BLOOD

ADAMTS13 gene deletion aggravates ischemic brain damage: a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion

(2009) M. Fujioka et al.   BLOOD

Platelet Polyphosphates Are Proinflammatory and Procoagulant Mediators In Vivo

(2009) Felicitas Müller et al.   CELL

Calcium signaling in platelets

(2009) D. VARGA-SZABO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Dabigatran versus Warfarin in Patients with Atrial Fibrillation

(2009) Stuart J. Connolly et al.   NEW ENGLAND JOURNAL OF MEDICINE

Orai1 (CRACM1) is the platelet SOC channel and essential for pathological thrombus formation

(2008) A. Braun et al.   BLOOD

Reduced incidence of ischemic stroke in patients with severe factor XI deficiency

(2008) O. Salomon et al.   BLOOD

Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment

(2008) G. Stoll et al.   BLOOD

Neuroprotection and glutamate attenuation by acetylsalicylic acid in temporary but not in permanent cerebral ischemia

(2008) C. Berger et al.   EXPERIMENTAL NEUROLOGY

The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction

(2008) David Varga-Szabo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Emergency Administration of Abciximab for Treatment of Patients With Acute Ischemic Stroke: Results of an International Phase III Trial

(2007) Harold P. Adams et al.   STROKE