Orai1 (CRACM1) is the platelet SOC channel and essential for pathological thrombus formation

Orai1 Mediates the Interaction between STIM1 and hTRPC1 and Regulates the Mode of Activation of hTRPC1-forming Ca2+Channels

(2008) Isaac Jardin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction

(2008) David Varga-Szabo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

(2008) Masatsugu Oh-hora et al.   NATURE IMMUNOLOGY

Mechanisms of Thrombus Formation

(2008) Bruce Furie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Store-operated Ca2+ entry in platelets occurs independently of transient receptor potential (TRP) C1

(2008) David Varga-Szabo et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Expression profiling and electrophysiological studies suggest a major role for Orai1 in the store-operated Ca2+influx pathway of platelets and megakaryocytes

(2008) Gwen Tolhurst et al.   PLATELETS

Functional relevance of the de novo coupling between hTRPC1 and type II IP3 receptor in store-operated Ca2+ entry in human platelets

(2007) Isaac Jardín et al.   CELLULAR SIGNALLING