Arterial thrombosis—insidious, unpredictable and deadly

The Perils of Combination Antithrombotic Therapy and Potential Resolutions

(2011) Marc Fisher et al.   CIRCULATION

Microparticles in Hemostasis and Thrombosis

(2011) A. Phillip Owens et al.   CIRCULATION RESEARCH

The evolution of antiplatelet therapy in cardiovascular disease

(2011) Omair Yousuf et al.   Nature Reviews Cardiology

Lack of P-selectin glycoprotein ligand-1 protects mice from thrombosis after collagen/epinephrine challenge

(2011) Kornél Miszti-Blasius et al.   THROMBOSIS RESEARCH

Scavenger receptor BI modulates platelet reactivity and thrombosis in dyslipidemia

(2010) Y. Ma et al.   BLOOD

Procoagulant platelets: are they necrotic?

(2010) S. P. Jackson et al.   BLOOD

Inhibition of the intrinsic coagulation pathway factor XI by antisense oligonucleotides: a novel antithrombotic strategy with lowered bleeding risk

(2010) H. Zhang et al.   BLOOD

Deletion of the p110  isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo

(2010) V. Martin et al.   BLOOD

Daily administration of the TP receptor antagonist terutroban improved endothelial function in high-cardiovascular-risk patients with atherosclerosis

(2010) Pierre-François Lesault et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Factor XIIa Inhibitor Recombinant Human Albumin Infestin-4 Abolishes Occlusive Arterial Thrombus Formation Without Affecting Bleeding

(2010) Ina Hagedorn et al.   CIRCULATION

Double-blind, placebo-controlled Phase II studies of the protease-activated receptor 1 antagonist E5555 (atopaxar) in Japanese patients with acute coronary syndrome or high-risk coronary artery disease

(2010) S. Goto et al.   EUROPEAN HEART JOURNAL

Phospholipid scramblase: An update

(2010) Edouard M. Bevers et al.   FEBS LETTERS

Nitric oxide signalling in the regulation of cardiovascular and platelet function

(2010) Eugenia Gkaliagkousi   Frontiers in Bioscience-Landmark

Arrestin-2 Differentially Regulates PAR4 and ADP Receptor Signaling in Platelets

(2010) Dongjun Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hageman factor, platelets and polyphosphates: early history and recent connection

(2010) J. CAEN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Calcium-dependent phospholipid scrambling by TMEM16F

(2010) Jun Suzuki et al.   NATURE

Antiplatelet therapies for the treatment of cardiovascular disease

(2010) Alan D. Michelson   NATURE REVIEWS DRUG DISCOVERY

The final steps of integrin activation: the end game

(2010) Sanford J. Shattil et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Impaired  IIb 3 Integrin Activation and Shear-Dependent Thrombus Formation in Mice Lacking Phospholipase D1

(2010) M. Elvers et al.   Science Signaling

Impaired activation of platelets lacking protein kinase C-  isoform

(2009) B. Nagy et al.   BLOOD

Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function

(2009) S. M. Schoenwaelder et al.   BLOOD

New insights into the haemostatic function of platelets

(2009) Andrew H. Wei et al.   BRITISH JOURNAL OF HAEMATOLOGY

Platelet Polyphosphates Are Proinflammatory and Procoagulant Mediators In Vivo

(2009) Felicitas Müller et al.   CELL

2009 Focused Updates: ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction (Updating the 2004 Guideline and 2007 Focused Update) and ACC/AHA/SCAI Guidelines on Percutaneous Coronary Intervention (Updating the 2005 Guideline and 2007 Focused Update)

(2009) Frederick G. Kushner et al.   CIRCULATION

Bleeding, Blood Transfusion, and Increased Mortality After Percutaneous Coronary Intervention

(2009) Brendan J. Doyle et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Risk of bleeding in patients with acute myocardial infarction treated with different combinations of aspirin, clopidogrel, and vitamin K antagonists in Denmark: a retrospective analysis of nationwide registry data

(2009) Rikke Sørensen et al.   LANCET

Safety and tolerability of SCH 530348 in patients undergoing non-urgent percutaneous coronary intervention: a randomised, double-blind, placebo-controlled phase II study

(2009) Richard C Becker et al.   LANCET

Platelet Adhesion under Flow

(2009) Zaverio M. Ruggeri   MICROCIRCULATION

A shear gradient–dependent platelet aggregation mechanism drives thrombus formation

(2009) Warwick S Nesbitt et al.   NATURE MEDICINE

Cell Adhesion Mechanisms in Platelets

(2008) David Varga-Szabo et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Orai1 (CRACM1) is the platelet SOC channel and essential for pathological thrombus formation

(2008) A. Braun et al.   BLOOD

R93W mutation in Orai1 causes impaired calcium influx in platelets

(2008) W. Bergmeier et al.   BLOOD

Reduced incidence of ischemic stroke in patients with severe factor XI deficiency

(2008) O. Salomon et al.   BLOOD

Antiplatelet Drugs

(2008) Carlo Patrono et al.   CHEST

The risk of iatrogenic bleeding in acute coronary syndromes and long-term mortality

(2008) Magdalena Sobieraj-Teague et al.   CURRENT OPINION IN CARDIOLOGY

What Makes Platelets Angry

(2008) Deepak L. Bhatt   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Complementary roles of platelets and coagulation in thrombus formation on plaques acutely ruptured by targeted ultrasound treatment: a novel intravital model

(2008) M. J. E. KUIJPERS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Mechanisms of Thrombus Formation

(2008) Bruce Furie et al.   NEW ENGLAND JOURNAL OF MEDICINE