Targeting of host organelles by pathogenic bacteria: a sophisticated subversion strategy

PLEKHM1 Regulates Salmonella-Containing Vacuole Biogenesis and Infection

(2015) David G. McEwan et al.   Cell Host & Microbe

Bacterial remodelling of the host epigenome: functional role and evolution of effectors methylating host histones

(2015) Monica Rolando et al.   CELLULAR MICROBIOLOGY

PLEKHM1 Regulates Autophagosome-Lysosome Fusion through HOPS Complex and LC3/GABARAP Proteins

(2015) David G. McEwan et al.   MOLECULAR CELL

Secretion systems in Gram-negative bacteria: structural and mechanistic insights

(2015) Tiago R. D. Costa et al.   NATURE REVIEWS MICROBIOLOGY

Live to die another way: modes of programmed cell death and the signals emanating from dying cells

(2015) Yaron Fuchs et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Post-translational modifications are key players of the Legionella pneumophila infection strategy

(2015) Céline Michard et al.   Frontiers in Microbiology

Bacterial Pathogen Manipulation of Host Membrane Trafficking

(2014) Seblewongel Asrat et al.   Annual Review of Cell and Developmental Biology

SnapShot: Histone Modifications

(2014) He Huang et al.   CELL

Vibrio cholerae T3SS Effector VopE Modulates Mitochondrial Dynamics and Innate Immune Signaling by Targeting Miro GTPases

(2014) Masato Suzuki et al.   Cell Host & Microbe

Diversity of bacterial manipulation of the host ubiquitin pathways

(2014) Yan Zhou et al.   CELLULAR MICROBIOLOGY

Shigella flexneri targets the HP1  subcode through the phosphothreonine lyase OspF

(2014) H. Harouz et al.   EMBO JOURNAL

A trip in the “New Microbiology” with the bacterial pathogen Listeria monocytogenes

(2014) Pascale Cossart et al.   FEBS LETTERS

The Salmonella Effector SteA Contributes to the Control of Membrane Dynamics of Salmonella-Containing Vacuoles

(2014) Lia Domingues et al.   INFECTION AND IMMUNITY

Expression of the Effector Protein IncD in Chlamydia trachomatis Mediates Recruitment of the Lipid Transfer Protein CERT and the Endoplasmic Reticulum-Resident Protein VAPB to the Inclusion Membrane

(2014) Hervé Agaisse et al.   INFECTION AND IMMUNITY

Histone Acetylation and Flagellin Are Essential for Legionella pneumophila-Induced Cytokine Expression

(2014) B. Schmeck et al.   JOURNAL OF IMMUNOLOGY

Bacteria–autophagy interplay: a battle for survival

(2014) Ju Huang et al.   NATURE REVIEWS MICROBIOLOGY

Legionella pneumophilaSubversion of Host Vesicular Transport by SidC Effector Proteins

(2014) Florian A. Horenkamp et al.   TRAFFIC

Legionella pneumophila type IV effectors hijack the transcription and translation machinery of the host cell

(2014) Monica Rolando et al.   TRENDS IN CELL BIOLOGY

Caspase crosstalk: integration of apoptotic and innate immune signalling pathways

(2014) Emma M. Creagh   TRENDS IN IMMUNOLOGY

A New Method To Determine In Vivo Interactomes Reveals Binding of the Legionella pneumophila Effector PieE to Multiple Rab GTPases

(2014) A. Mousnier et al.   mBio

Effector triggered manipulation of host immune response elicited by different pathotypes ofEscherichia coli

(2014) Elamparithi Jayamani et al.   Virulence

Legionella pneumophila Effector RomA Uniquely Modifies Host Chromatin to Repress Gene Expression and Promote Intracellular Bacterial Replication

(2013) Monica Rolando et al.   Cell Host & Microbe

A Rab-Centric Perspective of Bacterial Pathogen-Occupied Vacuoles

(2013) Racquel Kim Sherwood et al.   Cell Host & Microbe

The Legionella Effector RidL Inhibits Retrograde Trafficking to Promote Intracellular Replication

(2013) Ivo Finsel et al.   Cell Host & Microbe

Identification of a type IV secretion substrate ofBrucella abortusthat participates in the early stages of intracellular survival

(2013) Peter H. Döhmer et al.   CELLULAR MICROBIOLOGY

Salmonella T3SSs: successful mission of the secret(ion) agents

(2013) Thomas P Moest et al.   CURRENT OPINION IN MICROBIOLOGY

Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB

(2013) Emerich Mihai Gazdag et al.   EMBO REPORTS

SET-domain bacterial effectors target heterochromatin protein 1 to activate host rDNA transcription

(2013) Ting Li et al.   EMBO REPORTS

A bacterial protein promotes the recognition of theLegionella pneumophilavacuole by autophagy

(2013) Arwa A. Khweek et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Anthrax SET Protein

(2013) Shiraz Mujtaba et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reprogrammation épigénétique des cellules hôtes parLegionella pneumophila

(2013) Monica Rolando et al.   M S-MEDECINE SCIENCES

Exploitation of eukaryotic subcellular targeting mechanisms by bacterial effectors

(2013) Stuart W. Hicks et al.   NATURE REVIEWS MICROBIOLOGY

Searching algorithm for type IV secretion system effectors 1.0: a tool for predicting type IV effectors and exploring their genomic context

(2013) Damien F. Meyer et al.   NUCLEIC ACIDS RESEARCH

A Role for SIRT2-Dependent Histone H3K18 Deacetylation in Bacterial Infection

(2013) H. A. Eskandarian et al.   SCIENCE

Bacterial Subversion of Host Innate Immune Pathways

(2013) L. A. Baxt et al.   SCIENCE

Apoptosome Structure, Assembly, and Procaspase Activation

(2013) Shujun Yuan et al.   STRUCTURE

Dynamics of the Type III Secretion System Activity of Enteropathogenic Escherichia coli

(2013) E. Mills et al.   mBio

Genome Dynamics in Legionella: The Basis of Versatility and Adaptation to Intracellular Replication

(2013) L. Gomez-Valero et al.   Cold Spring Harbor Perspectives in Medicine

A Novel Membrane Sensor Controls the Localization and ArfGEF Activity of Bacterial RalF

(2013) Marcia Folly-Klan et al.   PLoS Pathogens

Brucella Modulates Secretory Trafficking via Multiple Type IV Secretion Effector Proteins

(2013) Sebenzile Myeni et al.   PLoS Pathogens

GTPase Networks in Membrane Traffic

(2012) Emi Mizuno-Yamasaki et al.   Annual Review of Biochemistry

The Legionella pneumophila Effector DrrA Is Sufficient to Stimulate SNARE-Dependent Membrane Fusion

(2012) Kohei Arasaki et al.   Cell Host & Microbe

Engineering commensal bacteria for prophylaxis against infection

(2012) Yih-Lin Goh et al.   CURRENT OPINION IN BIOTECHNOLOGY

Post-translational modifications of host proteins byLegionella pneumophila: a sophisticated survival strategy

(2012) Monica Rolando et al.   Future Microbiology

Coordination between RAB GTPase and phosphoinositide regulation and functions

(2012) Steve Jean et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The protein SdhA maintains the integrity of the Legionella-containing vacuole

(2012) E. A. Creasey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagosomes induced by a bacterial Beclin 1 binding protein facilitate obligatory intracellular infection

(2012) H. Niu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aggravating Genetic Interactions Allow a Solution to Redundancy in a Bacterial Pathogen

(2012) T. J. O'Connor et al.   SCIENCE

The Legionella Effector RavZ Inhibits Host Autophagy Through Irreversible Atg8 Deconjugation

(2012) A. Choy et al.   SCIENCE

Salmonella Inhibits Retrograde Trafficking of Mannose-6-Phosphate Receptors and Lysosome Function

(2012) K. McGourty et al.   SCIENCE

Secretive Bacterial Pathogens and the Secretory Pathway

(2012) Hubert Hilbi et al.   TRAFFIC

Parkinson's Disease–Associated Kinase PINK1 Regulates Miro Protein Level and Axonal Transport of Mitochondria

(2012) Song Liu et al.   PLoS Genetics

Legionella pneumophila Secretes a Mitochondrial Carrier Protein during Infection

(2012) Pavel Dolezal et al.   PLoS Pathogens

Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health

(2011) David C. Chan   Annual Review of Genetics

The pathogenic Escherichia coli type III secreted protease NleC degrades the host acetyltransferase p300

(2011) Stephanie R. Shames et al.   CELLULAR MICROBIOLOGY

Identification of a Brucella spp. secreted effector specifically interacting with human small GTPase Rab2

(2011) Marie de Barsy et al.   CELLULAR MICROBIOLOGY

OPERating ON Chromatin, a Colorful Language where Context Matters

(2011) Kathryn E. Gardner et al.   JOURNAL OF MOLECULAR BIOLOGY

A type III effector protease NleC from enteropathogenic Escherichia coli targets NF-κB for degradation

(2011) Jaclyn S. Pearson et al.   MOLECULAR MICROBIOLOGY

Legionella pneumophila SidD is a deAMPylase that modifies Rab1

(2011) Yunhao Tan et al.   NATURE

Modulation of Rab GTPase function by a protein phosphocholine transferase

(2011) Shaeri Mukherjee et al.   NATURE

Protein LidA from Legionella is a Rab GTPase supereffector

(2011) S. Schoebel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Listeria monocytogenestransiently alters mitochondrial dynamics during infection

(2011) Fabrizia Stavru et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Legionella pneumophila regulates the small GTPase Rab1 activity by reversible phosphorylcholination

(2011) Y. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Illuminating the landscape of host-pathogen interactions with the bacterium Listeria monocytogenes

(2011) P. Cossart   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retrograde vesicle transport in the Golgi

(2011) Nathanael P. Cottam et al.   PROTOPLASMA

De-AMPylation of the Small GTPase Rab1 by the Pathogen Legionella pneumophila

(2011) M. R. Neunuebel et al.   SCIENCE

A Bacterial Protein Targets the BAHD1 Chromatin Complex to Stimulate Type III Interferon Response

(2011) A. Lebreton et al.   SCIENCE

Salmonella-induced tubular networks

(2011) Nina Schroeder et al.   TRENDS IN MICROBIOLOGY

Chlamydia trachomatis Co-opts GBF1 and CERT to Acquire Host Sphingomyelin for Distinct Roles during Intracellular Development

(2011) Cherilyn A. Elwell et al.   PLoS Pathogens

Comparative and Functional Genomics of Legionella Identified Eukaryotic Like Proteins as Key Players in Host?Pathogen Interactions

(2011) Laura Gomez-Valero et al.   Frontiers in Microbiology

Modulation of Host Cell Function byLegionella pneumophilaType IV Effectors

(2010) Andree Hubber et al.   Annual Review of Cell and Developmental Biology

The Phosphoinositide Phosphatase SopB Manipulates Membrane Surface Charge and Trafficking of the Salmonella-Containing Vacuole

(2010) Malina A. Bakowski et al.   Cell Host & Microbe

Sorting nexin 3 (SNX3) is a component of a tubular endosomal network induced by Salmonella and involved in maturation of the Salmonella-containing vacuole

(2010) Virginie Braun et al.   CELLULAR MICROBIOLOGY

Multiple Host Proteins That Function in Phosphatidylinositol-4-Phosphate Metabolism Are Recruited to the Chlamydial Inclusion

(2010) A. M. Moorhead et al.   INFECTION AND IMMUNITY

Interactions between bacterial pathogens and mitochondrial cell death pathways

(2010) Thomas Rudel et al.   NATURE REVIEWS MICROBIOLOGY

Chlamydia trachomatis Intercepts Golgi-Derived Sphingolipids through a Rab14-Mediated Transport Required for Bacterial Development and Replication

(2010) Anahí Capmany et al.   PLoS One

The Legionella Effector Protein DrrA AMPylates the Membrane Traffic Regulator Rab1b

(2010) M. P. Muller et al.   SCIENCE

SKIP, the Host Target of the Salmonella Virulence Factor SifA, Promotes Kinesin-1-Dependent Vacuolar Membrane Exchanges

(2010) Audrey Dumont et al.   TRAFFIC

Anaplasma phagocytophilum Ats-1 Is Imported into Host Cell Mitochondria and Interferes with Apoptosis Induction

(2010) Hua Niu et al.   PLoS Pathogens

NleC, a Type III Secretion Protease, Compromises NF-κB Activation by Targeting p65/RelA

(2010) Hilo Yen et al.   PLoS Pathogens

Histone Methylation by NUE, a Novel Nuclear Effector of the Intracellular Pathogen Chlamydia trachomatis

(2010) Meghan E. Pennini et al.   PLoS Pathogens

Molecular mimicry: an important virulence strategy employed byLegionella pneumophilato subvert host functions

(2009) Tamara Nora et al.   Future Microbiology

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epigenetic Silencing of Host Cell Defense Genes Enhances Intracellular Survival of the Rickettsial Pathogen Anaplasma phagocytophilum

(2009) Jose C. Garcia-Garcia et al.   PLoS Pathogens

Real-Time Analysis of Effector Translocation by the Type III Secretion System of Enteropathogenic Escherichia coli

(2008) Erez Mills et al.   Cell Host & Microbe

Structure and Function of Salmonella SifA Indicate that Its Interactions with SKIP, SseJ, and RhoA Family GTPases Induce Endosomal Tubulation

(2008) Maikke B. Ohlson et al.   Cell Host & Microbe

TheLegionella pneumophilaphosphatidylinositol-4 phosphate-binding type IV substrate SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole

(2008) Curdin Ragaz et al.   CELLULAR MICROBIOLOGY

The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth ofLegionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE

(2008) Stefan S. Weber et al.   CELLULAR MICROBIOLOGY

Import of bacterial pathogenicity factors into mitochondria

(2008) Vera Kozjak-Pavlovic et al.   CURRENT OPINION IN MICROBIOLOGY

SopB promotes phosphatidylinositol 3-phosphate formation onSalmonellavacuoles by recruiting Rab5 and Vps34

(2008) Gustavo V. Mallo et al.   JOURNAL OF CELL BIOLOGY

Sorting nexin-1 defines an early phase of Salmonella-containing vacuole-remodeling during Salmonella infection

(2008) M. V. Bujny et al.   JOURNAL OF CELL SCIENCE

Virulence blockers as alternatives to antibiotics: type III secretion inhibitors against Gram-negative bacteria

(2008) P. Keyser et al.   JOURNAL OF INTERNAL MEDICINE

Chlamydia causes fragmentation of the Golgi compartment to ensure reproduction

(2008) Dagmar Heuer et al.   NATURE

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

(2008) Ralph R. Isberg et al.   NATURE REVIEWS MICROBIOLOGY

Ankyrin Repeat Proteins Comprise a Diverse Family of Bacterial Type IV Effectors

(2008) X. Pan et al.   SCIENCE

Legionella Eukaryotic-Like Type IV Substrates Interfere with Organelle Trafficking

(2008) Karim Suwwan de Felipe et al.   PLoS Pathogens

SNARE Protein Mimicry by an Intracellular Bacterium

(2008) Cédric Delevoye et al.   PLoS Pathogens

The versatility of Shigella effectors

(2007) Michinaga Ogawa et al.   NATURE REVIEWS MICROBIOLOGY