Review
Astronomy & Astrophysics
Thomas J. Immel, Scott L. England, Brian J. Harding, Yen-Jung Wu, Astrid Maute, Chihoko Cullens, Christoph R. Englert, Stephen B. Mende, Roderick A. Heelis, Harald U. Frey, Eric J. Korpela, Andrew W. Stephan, Sabine Frey, Michael H. Stevens, Jonathan J. Makela, Farzad Kamalabadi, Colin C. Triplett, Jeffrey M. Forbes, Emma McGinness, L. Claire Gasque, John M. Harlander, Jean-C. Gerard, Benoit Hubert, Joseph D. Huba, Robert R. Meier, Bryce Roberts
Summary: The two-year prime mission of NASA's Ionospheric Connection Explorer (ICON) has been successfully completed, exceeding the baseline objectives. Through a detailed mission design, ICON has provided unique and synergistic measurements to investigate the behavior of the ionosphere-thermosphere system. It has revealed remarkable effects in the ionosphere caused by energetic inputs from the lower and middle atmosphere, shedding light on the transmission of these effects to the peak of plasma density.
SPACE SCIENCE REVIEWS
(2023)
Article
Microbiology
Sushmita Sridhar, Sally Forrest, Derek Pickard, Claire Cormie, Emily A. Lees, Nicholas R. Thomson, Gordon Dougan, Stephen Baker
Summary: Antimicrobial resistance is a critical global health crisis, with rising resistance to fluoroquinolones such as ciprofloxacin. Research has shown that clinical isolates of Salmonella enterica serovar Typhimurium adapt to high concentrations of ciprofloxacin in a way that promotes intracellular survival, with different isolates responding heterogeneously to the drug.
Editorial Material
Chemistry, Physical
Qiangfei Xia, J. Joshua Yang, Rivu Midya
Summary: A disordered network of nanowires controlled by thermodynamics is used as a physical 'reservoir' for processing spatiotemporal information in a memristive implementation of reservoir computing.
Article
Biochemistry & Molecular Biology
Serena Ammendola, Valerio Secli, Francesca Pacello, Martina Bortolami, Fabiana Pandolfi, Antonella Messore, Roberto Di Santo, Luigi Scipione, Andrea Battistoni
Summary: The chelating agent DFP effectively inhibits the growth of Pseudomonas aeruginosa but not Salmonella enterica serovar Typhimurium. Different Fe-dependent genes of the two pathogens respond differently to DFP. Some derivatives of DFP show a greater ability to interfere with Fe homeostasis in STM compared to DFP, suggesting the possibility of obtaining derivatives with broader antimicrobial action.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Logan Gildea, Joseph Atia Ayariga, Olufemi S. Ajayi, Junhuan Xu, Robert Villafane, Michelle Samuel-Foo
Summary: This study examines the antibacterial potential of CBD against Salmonella and demonstrates its efficacy through biological assays. Comparative studies also reveal the potential resistance development of Salmonella against CBD treatment.
Article
Multidisciplinary Sciences
Peter Stout
Summary: Houston, TX had a well-known failure in its police forensic laboratory, but the Houston Forensic Science Center (HFSC) has successfully remediated past failures and improved public trust in forensic testing, becoming a model for other labs. HFSC's blind testing program has provided valuable insights into the challenges faced by forensic laboratories. These challenges include poor-quality evidence, interconnectedness with the criminal justice system, and the need for oversight and regulatory frameworks.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Agronomy
Sainan Zhang, Shengcai Han, Xiaofang Yu, Julin Gao, Shuping Hu, Naoganchaolu Borjigin, Qinggeer Borjigin, Jiangan Guo, Jianfei Bai, Bizhou Zhang, Zhiyuan Huang, Yong Lei
Summary: Solid bacterial agents were screened to degrade stover at low temperatures, using corn stover powder, starch, and bran as additives. The optimal formulation had a 1:4 ratio of precipitates and additives, with a 4:3:9 ratio of corn stover powder, starch, and bran. This formulation showed higher degradation effects on stover and its components, particularly lignin, both in lab soil culture simulation and field environment, and had a high viable bacterial count and lignocellulase activities.
Article
Dermatology
Lisa Zhai, Kiran Motaparthi
Summary: Building a successful culture in academic dermatology is essential due to the shortage of dermatologists in academia, which raises concerns about the training of future physicians and the progress of innovative research. Recruitment and retention of dermatologists face challenges from academic demands and the private sector. Addressing barriers to a career in academia and retaining faculty are crucial to avoid leadership gaps.
CLINICS IN DERMATOLOGY
(2022)
Article
Dermatology
Lisa Zhai, Kiran Motaparthi
Summary: Building a successful culture in academic dermatology is crucial due to the shortage of dermatologists, especially academicians. The recruitment and retention of dermatologists in academia faces challenges from increasing demands in academic medicine and the allure of the private sector. Efforts should be made to address barriers to a career in academia and retain faculty already in academia.
CLINICS IN DERMATOLOGY
(2023)
News Item
Physics, Multidisciplinary
Julie Plastino
Summary: Biomolecular condensates enable compartmentalization and concentration of cellular components independent of lipid membranes. The protein VASP has been found to condense, leading to the reshaping of actin, a critical component of the cell cytoskeleton.
Editorial Material
Biochemistry & Molecular Biology
Elise Bornet, Alexander J. Westermann
Summary: This article discusses the increasing use of Bacteroides spp. as model gut commensals in cocolonization studies and their divergent roles in protecting against or promoting infection. It also explores the potential of cutting-edge transcriptomics in unraveling the molecular basis of these roles.
TRENDS IN MICROBIOLOGY
(2022)
Article
Automation & Control Systems
K. L. Yung, Y. P. Tsang, C. H. Wu, W. H. Ip
Summary: In recent aerospace missions, space logistics play a crucial role in storing, delivering, and returning crew and materials. Unlike traditional commercial logistics, space logistics are expensive and mission-driven, with a long replenishment cycle. This study extends the theory of the inventory packing problem to develop autonomous agents that interact within a space logistics decision support system to enhance replenishment decisions, optimize chunk loading, and ensure quality inspection.
Article
Computer Science, Artificial Intelligence
Rahul Kala
Summary: This paper studies the problem of giving complex instructions to a robot using expression trees. A greedy solution algorithm is proposed followed by optimization using a Genetic Algorithm. Experimental results show that the proposed approach outperforms other solutions for large problem sizes that cannot be solved using traditional techniques.
APPLIED SOFT COMPUTING
(2023)
Article
Agriculture, Dairy & Animal Science
Rasha M. M. Abou Elez, Ibrahim Elsohaby, Nashwa El-Gazzar, Hala M. N. Tolba, Eman N. Abdelfatah, Samah S. Abdellatif, Ahmed Atef Mesalam, Asmaa B. M. B. Tahoun
Summary: Salmonella enterica is a common foodborne pathogen causing gastrointestinal signs in a variety of hosts. The overuse of antibiotics in poultry has led to the emergence of multidrug-resistant microorganisms. Biosynthesized silver nanoparticles (AgNPs) show promise as alternative antimicrobial agents against MDR Salmonella. This study evaluated the effectiveness of AgNPs on MDR S. enteritidis and S. typhimurium isolates from laying hens, eggs, and humans, suggesting potential use in laying hen farms.
Article
Microbiology
Anice Sabag-Daigle, Erin F. Boulanger, Pankajavalli Thirugnanasambantham, Jamison D. Law, Alex J. Bogard, Edward J. Behrman, Venkat Gopalan, Brian M. M. Ahmer
Summary: Nontyphoidal salmonellosis is a significant foodborne disease globally, with no vaccines available for prevention and antibiotic resistance on the rise. The FraB gene is identified to cause fitness attenuation in Salmonella. Small-molecule inhibitors of FraB have been discovered, showing potential as therapeutics to reduce the severity of Salmonella infections.
MICROBIOLOGY SPECTRUM
(2023)
Article
Multidisciplinary Sciences
Weidong Zhao, Thomas Moest, Yaya Zhao, Aude-Agnes Guilhon, Christophe Buffat, Jean-Pierre Gorvel, Stephane Meresse
SCIENTIFIC REPORTS
(2015)
Article
Cell Biology
Alexandra Vergnes, Julie P. M. Viala, Rabah Ouadah-Tsabet, Berengere Pocachard, Laurent Loiseau, Stephane Meresse, Frederic Barras, Laurent Aussel
CELLULAR MICROBIOLOGY
(2017)
Article
Immunology
Yaya Zhao, Jean-Pierre Gorvel, Stephane Meresse
Editorial Material
Immunology
Lucrecia Alberdi, Stephane Meresse
Article
Immunology
Lautaro Diacovich, Lucia Lorenzi, Mauro Tomassetti, Stephane Meresse, Hugo Gramajo
Article
Genetics & Heredity
Julie P. Viala, Valerie Prima, Remy Puppo, Rym Agrebi, Mickael J. Canestrari, Sabrina Lignon, Nicolas Chauvin, Stephane Meresse, Tam Mignot, Regine Lebrun, Emmanuelle Bouveret
Article
Cell Biology
Thomas Moest, Weidong Zhao, Yaya Zhao, Jan Moritz Schussler, Wen Yan, Jean-Pierre Gorvel, Stephane Meresse
CELLULAR MICROBIOLOGY
(2018)
Article
Immunology
Matthieu Million, Maxime Gaudin, Clea Melenotte, Lionel Chasson, Sophie Edouard, Constance Verdonk, Elsa Prudent, Bernard Amphoux, Stephane Meresse, Richard Dorent, Hubert Lepidi, Bernard La Scola, Jean-Pierre Gorvel, Christelle Desnues, Didier Raoult
CLINICAL INFECTIOUS DISEASES
(2020)
Article
Cell Biology
Clara Degos, Lisiena Hysenaj, Gabriela Gonzalez-Espinoza, Vilma Arce-Gorvel, Aurelie Gagnaire, Alexia Papadopoulos, Karina Alejandra Pasquevich, Stephane Meresse, Juliana Cassataro, Sylvie Memet, Jean-Pierre Gorvel
CELLULAR MICROBIOLOGY
(2020)
Article
Cell Biology
Lucrecia Alberdi, Alexandra Vergnes, Jean-Baptiste Manneville, Dumizulu L. Tembo, Ziyan Fang, Yaya Zhao, Nina Schroeder, Audrey Dumont, Margaux Lagier, Patricia Bassereau, Lorena Redondo-Morata, Jean-Pierre Gorvel, Stephane Meresse
JOURNAL OF CELL SCIENCE
(2020)
Article
Microbiology
Fernando Chimal-Cazares, Gabriela Hernandez-Martinez, Sabino Pacheco, Miguel A. Ares, Jorge Soria-Bustos, Manuel Sanchez-Gutierrez, Jeannett A. Izquierdo-Vega, Jose Antonio Ibarra, Jorge A. Gonzalez-Y-Merchand, Jean-Pierre Gorvel, Stephane Meresse, Miguel A. De la Cruz
FRONTIERS IN MICROBIOLOGY
(2020)
Review
Cell Biology
Jona Karam, Stephane Meresse, Laurent Kremer, Wassim Daher
CELLULAR MICROBIOLOGY
(2020)
Article
Multidisciplinary Sciences
Thanida Laopanupong, Pinidphon Prombutara, Phongthon Kanjanasirirat, Salisa Benjaskulluecha, Atsadang Boonmee, Tanapat Palaga, Stephane Meresse, Jiraporn Paha, Tegar Adriansyah Putra Siregar, Tanawadee Khumpanied, Suparerk Borwornpinyo, Angkana Chaiprasert, Pongsak Utaisincharoen, Marisa Ponpuak
Summary: This study showed that specific genes such as Kxd1 and Plekhm2 are upregulated in macrophages infected with autophagy-resistant Beijing strain of Mycobacterium tuberculosis, compared to those infected with the reference strain H37Rv, leading to suppression of lysosome positioning and delivery during starvation-induced autophagy. These genes play a crucial role in allowing the BJN strain to evade autophagic restriction and survive within host cells.
SCIENTIFIC REPORTS
(2021)
Article
Cell Biology
Ziyan Fang, Mathieu Fallet, Thomas Moest, Jean-Pierre Gorvel, Stephane Meresse
Summary: In this study, it was found that the microtubule molecular motor KIF1B beta plays a key role in the establishment of the Salmonella replication niche, and its absence affects the stability of bacterial vacuoles and the formation of associated tubules. Kinesin-3 interacts with the Salmonella effector SifA and the host protein complex SKIP. The presence of SifA establishes a recruitment pathway for kinesin-1 and kinesin-3 in infected cells.
JOURNAL OF CELL SCIENCE
(2022)
Article
Multidisciplinary Sciences
S. Holbert, E. Barilleau, S. M. Roche, J. Trotereau, S. Georgeault, J. Burlaud-Gaillard, A. Wiedemann, S. Meresse, I Virlogeux-Payant, P. Velge
Summary: Numerous studies have shown that the Salmonella Pathogenicity Island 1-encoded type III secretion system (T3SS1) apparatus and its associated effectors play a key role in the invasion and intracellular fate of Salmonella in host cells. Some cell lines have been identified where Salmonella Typhimurium can enter without using its three known invasion factors. In the murine AML12 hepatocyte cell line, the T3SS1 mutant induced an intracellular fate similar to the wild-type strain, indicating that invasion and survival of Salmonella Typhimurium can be independent of T3SS1.
SCIENTIFIC REPORTS
(2021)