STAT5 is a potent negative regulator of TFHcell differentiation

STAT3-Mediated Up-Regulation of BLIMP1 Is Coordinated with BCL6 Down-Regulation to Control Human Plasma Cell Differentiation

(2014) S. A. Diehl et al.   JOURNAL OF IMMUNOLOGY

B7RP-1 Blockade Ameliorates Autoimmunity through Regulation of Follicular Helper T Cells

(2014) Y.-L. Hu et al.   JOURNAL OF IMMUNOLOGY

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

Opposing Signals from the Bcl6 Transcription Factor and the Interleukin-2 Receptor Generate T Helper 1 Central and Effector Memory Cells

(2011) Marion Pepper et al.   IMMUNITY

ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6

(2011) Youn Soo Choi et al.   IMMUNITY

Bcl6 Protein Expression Shapes Pre-Germinal Center B Cell Dynamics and Follicular Helper T Cell Heterogeneity

(2011) Masahiro Kitano et al.   IMMUNITY

B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells

(2011) Sau K. Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Dendritic Cell-Restricted Antigen Presentation Initiates the Follicular Helper T Cell Program but Cannot Complete Ultimate Effector Differentiation

(2011) R. Goenka et al.   JOURNAL OF IMMUNOLOGY

BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR–ABL1 kinase inhibition

(2011) Cihangir Duy et al.   NATURE

Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages

(2011) Wei Liao et al.   NATURE IMMUNOLOGY

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

(2011) Erika Cretney et al.   NATURE IMMUNOLOGY

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

(2011) Xiang-Ping Yang et al.   NATURE IMMUNOLOGY

IL-21 and IL-6 Are Critical for Different Aspects of B Cell Immunity and Redundantly Induce Optimal Follicular Helper CD4 T Cell (Tfh) Differentiation

(2011) Danelle Eto et al.   PLoS One

Late Interleukin-6 Escalates T Follicular Helper Cell Responses and Controls a Chronic Viral Infection

(2011) J. A. Harker et al.   SCIENCE

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

Signal transduction pathways and transcriptional regulation in Th17 cell differentiation

(2010) Kiyoshi Hirahara et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Prolonged Interleukin-2Rα Expression on Virus-Specific CD8+ T Cells Favors Terminal-Effector Differentiation In Vivo

(2010) Vandana Kalia et al.   IMMUNITY

Interleukin-2 and Inflammation Induce Distinct Transcriptional Programs that Promote the Differentiation of Effector Cytolytic T Cells

(2010) Matthew E. Pipkin et al.   IMMUNITY

Follicular Helper T Cell Differentiation Requires Continuous Antigen Presentation that Is Independent of Unique B Cell Signaling

(2010) Elissa K. Deenick et al.   IMMUNITY

The germinal center reaction

(2010) Dominique Gatto et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

STAT5 Is Critical To Maintain Effector CD8+ T Cell Responses

(2010) P. Tripathi et al.   JOURNAL OF IMMUNOLOGY

Germinal Center T Follicular Helper Cell IL-4 Production Is Dependent on Signaling Lymphocytic Activation Molecule Receptor (CD150)

(2010) I. Yusuf et al.   JOURNAL OF IMMUNOLOGY

In Vivo Regulation of Bcl6 and T Follicular Helper Cell Development

(2010) A. C. Poholek et al.   JOURNAL OF IMMUNOLOGY

Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation

(2010) Shane Crotty et al.   NATURE IMMUNOLOGY

The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment

(2009) Di Yu et al.   IMMUNITY

Analysis of Interleukin-21-Induced Prdm1 Gene Regulation Reveals Functional Cooperation of STAT3 and IRF4 Transcription Factors

(2009) Hyokjoon Kwon et al.   IMMUNITY

Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH ) cell lineage is induced by IL-12

(2009) Cindy S Ma et al.   IMMUNOLOGY AND CELL BIOLOGY

Follicular helper T cells are required for systemic autoimmunity

(2009) Michelle A. Linterman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding

(2009) Nicolas Fazilleau et al.   NATURE IMMUNOLOGY

Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase

(2009) M. Gigoux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

Bcl6 Mediates the Development of T Follicular Helper Cells

(2009) R. I. Nurieva et al.   SCIENCE

Regulation and Functions of Blimp-1 in T and B Lymphocytes

(2008) Gislâine Martins et al.   Annual Review of Immunology

Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages

(2008) Roza I. Nurieva et al.   IMMUNITY

Fluorescent protein FRET pairs for ratiometric imaging of dual biosensors

(2008) Hui-wang Ai et al.   NATURE METHODS

New insights into the roles of Stat5a/b and Stat3 in T cell development and differentiation

(2008) Lai Wei et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY