TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4+ T cell fate and interact with Runx3 to silence Cd4 in CD8+ T cells

A far downstream enhancer for murine Bcl11b controls its T-cell specific expression

(2013) L. Li et al.   BLOOD

TCF-1 mediates repression of Notch pathway in T lineage-committed early thymocytes

(2013) S. Yu et al.   BLOOD

Runx3-mediated Transcriptional Program in Cytotoxic Lymphocytes

(2013) Joseph Lotem et al.   PLoS One

Regulation of mature T cell responses by the Wnt signaling pathway

(2012) Hai-Hui Xue et al.   Annals of the New York Academy of Sciences

The TCF-1 and LEF-1 Transcription Factors Have Cooperative and Opposing Roles in T Cell Development and Malignancy

(2012) Shuyang Yu et al.   IMMUNITY

Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus

(2012) Tom M. McCaughtry et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Nuclear Effector of Wnt-Signaling, Tcf1, Functions as a T-Cell–Specific Tumor Suppressor for Development of Lymphomas

(2012) Machteld M. Tiemessen et al.   PLOS BIOLOGY

Tcf7 Is an Important Regulator of the Switch of Self-Renewal and Differentiation in a Multipotential Hematopoietic Cell Line

(2012) Jia Qian Wu et al.   PLoS Genetics

MEME-ChIP: motif analysis of large DNA datasets

(2011) Philip Machanick et al.   BIOINFORMATICS

A critical role for TCF-1 in T-lineage specification and differentiation

(2011) Brittany Nicole Weber et al.   NATURE

T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling

(2011) K. Germar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T-cell lineage determination

(2010) Qi Yang et al.   IMMUNOLOGICAL REVIEWS

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

(2010) Jung-Hyun Park et al.   NATURE IMMUNOLOGY

CD4-CD8 Lineage Differentiation: Thpok-ing into the Nucleus

(2009) L. Wang et al.   JOURNAL OF IMMUNOLOGY

mTOR regulates memory CD8 T-cell differentiation

(2009) Koichi Araki et al.   NATURE

RUNX3 Attenuates β-Catenin/T Cell Factors in Intestinal Tumorigenesis

(2008) Kosei Ito et al.   CANCER CELL

CD4-CD8 Lineage Commitment Is Regulated by a Silencer Element at the ThPOK Transcription-Factor Locus

(2008) Xi He et al.   IMMUNITY

Decision by committee: new light on the CD4/CD8-lineage choice

(2008) Ellen V Rothenberg   IMMUNOLOGY AND CELL BIOLOGY

Development of all CD4 T lineages requires nuclear factor TOX

(2008) Parinaz Aliahmad et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate

(2008) Sawako Muroi et al.   NATURE IMMUNOLOGY

ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage

(2008) Takeshi Egawa et al.   NATURE IMMUNOLOGY

Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4+ T cells

(2008) Lie Wang et al.   NATURE IMMUNOLOGY

Repression of the Transcription Factor Th-POK by Runx Complexes in Cytotoxic T Cell Development

(2008) R. Setoguchi et al.   SCIENCE

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY