Review of aerobic glycolysis and its key enzymes - new targets for lung cancer therapy

Targeting Lactate Dehydrogenase-A Inhibits Tumorigenesis and Tumor Progression in Mouse Models of Lung Cancer and Impacts Tumor-Initiating Cells

(2014) Han Xie et al.   Cell Metabolism

Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer

(2013) Krushna C. Patra et al.   CANCER CELL

Altered Glutamine Metabolism and Therapeutic Opportunities for Lung Cancer

(2013) Amr Mohamed et al.   Clinical Lung Cancer

Targeting 6-Phosphofructo-2-Kinase (PFKFB3) as a Therapeutic Strategy against Cancer

(2013) B. F. Clem et al.   MOLECULAR CANCER THERAPEUTICS

Pharmacologic Activation of PKM2 Slows Lung Tumor Xenograft Growth

(2013) K. M. Parnell et al.   MOLECULAR CANCER THERAPEUTICS

Demonstration program of population-based lung cancer screening in China: Rationale and study design

(2013) Qinghua Zhou et al.   Thoracic Cancer

Oxidative stress-responsive microRNA-320 regulates glycolysis in diverse biological systems

(2012) Huibin Tang et al.   FASEB JOURNAL

MicroRNA-143 (miR-143) Regulates Cancer Glycolysis via Targeting Hexokinase 2 Gene

(2012) Rong Fang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lung cancer incidence and mortality in China, 2009

(2012) Wanqing Chen et al.   Thoracic Cancer

nm23-H1 gene driven by hTERT promoter induces inhibition of invasive phenotype and metastasis of lung cancer xenograft in mice

(2012) Yu Fan et al.   Thoracic Cancer

Poor outcome in primary non-small cell lung cancers is predicted by transketolase TKTL1 expression

(2011) Gian Kayser et al.   PATHOLOGY

Lactate-Dehydrogenase 5 is overexpressed in non-small cell lung cancer and correlates with the expression of the transketolase-like protein 1

(2010) Gian Kayser et al.   Diagnostic Pathology

Efficacy of RNAi targeting of pyruvate kinase M2 combined with cisplatin in a lung cancer model

(2010) Wenhao Guo et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Upregulation of Hypoxia-Inducible Factor-1α mRNA and its Clinical Significance in Non-small Cell Lung Cancer

(2010) Tomofumi Yohena et al.   Journal of Thoracic Oncology

Evaluation on the incidence, mortality and tendency of lung cancer in China

(2010) Wanqing Chen et al.   Thoracic Cancer

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

(2009) Charles J. David et al.   NATURE

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

(2008) Heather R. Christofk et al.   NATURE