Omega-3 fatty acids protect from diet-induced obesity, glucose intolerance, and adipose tissue inflammation through PPARγ-dependent and PPARγ-independent actions

PPARγ activation attenuates glucose intolerance induced by mTOR inhibition with rapamycin in rats

(2014) William T. Festuccia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects

(2014) Mark M. Yore et al.   CELL

Endogenous ω-3 Polyunsaturated Fatty Acid Production Confers Resistance to Obesity, Dyslipidemia, and Diabetes in Mice

(2014) Jie Li et al.   MOLECULAR ENDOCRINOLOGY

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Elevated tissue omega-3 fatty acid status prevents age-related glucose intolerance in fat-1 transgenic mice

(2013) Talita Romanatto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Impaired Local Production of Proresolving Lipid Mediators in Obesity and 17-HDHA as a Potential Treatment for Obesity-Associated Inflammation

(2013) A. Neuhofer et al.   DIABETES

Enhanced peroxisomal β-oxidation is associated with prevention of obesity and glucose intolerance by fish oil-enriched diets

(2013) J. Fiamoncini et al.   Obesity

The Development of a Specific and Sensitive LC-MS-Based Method for the Detection and Quantification of Hydroperoxy- and Hydroxydocosahexaenoic Acids as a Tool for Lipidomic Analysis

(2013) Priscilla B. M. C. Derogis et al.   PLoS One

Fatty Acids Regulate Endothelial Lipase and Inflammatory Markers in Macrophages and in Mouse Aorta

(2012) Un Ju Jung et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mechanisms of Action of (n-3) Fatty Acids

(2012) Philip C. Calder   JOURNAL OF NUTRITION

Mammary tumor development is directly inhibited by lifelong n-3 polyunsaturated fatty acids

(2012) Mira B. MacLennan et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Adaptive immunity in obesity and insulin resistance

(2012) Henrike Sell et al.   Nature Reviews Endocrinology

Omega-3 fatty acids induce apoptosis in human breast cancer cells and mouse mammary tissue through syndecan-1 inhibition of the MEK-Erk pathway

(2011) H. Sun et al.   CARCINOGENESIS

High Pancreatic n-3 Fatty Acids Prevent STZ-Induced Diabetes in Fat-1 Mice: Inflammatory Pathway Inhibition

(2011) J. Bellenger et al.   DIABETES

5-Lipoxygenase Metabolite 4-HDHA Is a Mediator of the Antiangiogenic Effect of  -3 Polyunsaturated Fatty Acids

(2011) P. Sapieha et al.   Science Translational Medicine

GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects

(2010) Da Young Oh et al.   CELL

Antiobesity Effect of Eicosapentaenoic Acid in High-Fat/High-Sucrose Diet-Induced Obesity: Importance of Hepatic Lipogenesis

(2010) A. Sato et al.   DIABETES

Transgenic Restoration of Long-Chain n-3 Fatty Acids in Insulin Target Tissues Improves Resolution Capacity and Alleviates Obesity-Linked Inflammation and Insulin Resistance in High-Fat-Fed Mice

(2010) P. J. White et al.   DIABETES

Mechanisms underlying the cardioprotective effects of omega-3 polyunsaturated fatty acids

(2010) Yuriko Adkins et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Omega-3 fatty acids attenuate dendritic cell function via NF-κB independent of PPARγ

(2010) Eve Draper et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The PPARγ agonist rosiglitazone enhances rat brown adipose tissue lipogenesis from glucose without altering glucose uptake

(2009) William T. Festuccia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Selective effects of PPARγ agonists and antagonists on human pre-adipocyte differentiation

(2009) C. Leyvraz et al.   DIABETES OBESITY & METABOLISM

Obesity-induced insulin resistance and hepatic steatosis are alleviated by ω-3 fatty acids: a role for resolvins and protectins

(2009) Ana González-Périz et al.   FASEB JOURNAL

Rosiglitazone-induced heart remodelling is associated with enhanced turnover of myofibrillar protein and mTOR activation

(2009) William T. Festuccia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Importance of the Omega-6/Omega-3 Fatty Acid Ratio in Cardiovascular Disease and Other Chronic Diseases

(2008) Artemis P. Simopoulos   EXPERIMENTAL BIOLOGY AND MEDICINE